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Found 522 clinical trials
Community Outreach for Palliative Engagement -- Parkinson Disease (COPE-PD)

The purpose of this study is to learn more about the effectiveness of palliative care training for community physicians and telemedicine support services for patients and carepartners with Parkinson's disease and Lewy Body Dementia (LBD) or related conditions and their care partners. Palliative care is a treatment approach focused on …

supranuclear palsy
atrophy
parkinsonism
lewy body dementia
progressive supranuclear palsy
  • 0 views
  • 10 May, 2022
  • 1 location
Recovering Damaged Cells for Sequelae Caused by COVID-19 SARS-CoV-2

Post-acute sequelae of SARS-CoV-2 infection can cause multiple system function disorders, and complicated symptoms last for an extended period. The virus can cause this continued infection, or the virus causes immune system function disorder and post-infectious autoimmune disease. The clinical symptoms can be smell loss, taste loss to liver function …

  • 25 views
  • 02 Jun, 2021
  • 1 location
"Parkinson AKTIV - Non-pharmacological Treatments in an Innovative Parkinson's Network" (ParkinsonAKTIV)

The purpose of this study is to evaluate the efficacy of an online platform that allows neurologists and therapists to exchange therapy recommendations, communicate assessments and plan physical therapy, occupational therapy as well as speech and swallowing therapy for their patients.

  • 2 views
  • 15 Mar, 2022
  • 1 location
Parkinson's Foundation PD GENEration Genetic Registry

Development of a central repository for PD-related genomic data for future research.

movement disorder
  • 0 views
  • 25 Jan, 2022
  • 5 locations
Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease (ADAPT-PD)

The purpose of the study is to demonstrate the safety and effectiveness of adaptive DBS (aDBS) for Parkinson's disease.

  • 44 views
  • 30 May, 2022
  • 12 locations
A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia

This is a Phase 2b study investigating the efficacy and safety of mesdopetam as adjunct therapy on daily ON-time without troublesome dyskinesia in patients with Parkinson disease. Mesdopetam is taken for 84 days.

dyskinesia
apomorphine
levodopa
  • 0 views
  • 24 Mar, 2022
  • 28 locations
CHIEF PD (CHolinesterase Inhibitor to prEvent Falls in Parkinson's Disease) (CHIEF PD)

Parkinson's disease is a common condition particularly affecting older people. Falls are a very frequent complication of the disease affecting 60% of people with Parkinson's every year. As the population ages, the number of people living with Parkinson's disease and the occurrence of complications will increase. The loss of the …

dopamine
  • 37 views
  • 23 Feb, 2022
  • 27 locations
Open-label Trial in Parkinson's Disease (PD) (TEMPO-4)

The purpose of this study is to evaluate the safety and efficacy of long-term administration of flexible doses of tavapadon in participants with Parkinson's Disease.

bradykinesia
amantadine
levodopa
carbidopa
  • 0 views
  • 14 Jun, 2022
  • 61 locations
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease (PADOVA)

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.

SPECT Scan
parkinsonism
dopamine transporter
bradykinesia
early parkinson's
  • 1 views
  • 19 Jun, 2022
  • 105 locations
A Study in Parkinson's Disease in Patients With Moderate to Severe Dyskinesia (ASTORIA)

The current study will explore the efficacy, safety and tolerability of 2 dose combinations of JM-010 to determine the optimal doses of each component to be studied in confirmatory clinical trials.

dyskinesia
parkinson's disease
levodopa
combinations
  • 10 views
  • 02 May, 2022
  • 4 locations