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Found 525 clinical trials
Featured trial
A Randomized, Double-Blind, Double-Dummy, Active-Controlled Study Comparing the Efficacy, Safety and Tolerability of ABBV-951 to Oral Carbidopa/Levodopa in Advanced Parkinson's Disease Patients

The purpose of this study is to find out how well ABBV-951 works to control Parkinson's disease symptoms compared to oral Carbidopa (CD)/Levodopa (LD). The study is also seeking to test whether ABBV-951 is well tolerated in subjects with Parkinson's disease.

levodopa
carbidopa
  • 132 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Black and African American Connections to Parkinson’s Disease (BLAAC PD) Study  

BLAAC PD aims to learn more about gene changes that may cause Parkinson’s in Black and African American people. This new data could lead to future Parkinson’s tests and treatments for Black and African American people. And it may help better understand disease in other groups too. You can join …

Accepts healthy volunteers
movement disorder
  • 476 views
  • 14 Jun, 2022
  • 3 locations
Featured trial
Parkinson’s Disease (Observational Study)

Do you or a loved one have Parkinson’s disease? Learn more about an observational clinical research study for individuals who have, or are at risk for, Parkinson’s disease.  

  • 193 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Genotypic Influences on Network Progression in Parkinson's Disease

The goal of this research study is to help scientists better understand how mutations in the GBA (glucocerebrosidase beta acid) gene affects patients with Parkinson’s disease. Mutations in the GBA gene are the most common genetic risk factors for Parkinson's, affecting about 10 percent of the more than 6 million …

antiparkinsonian agents
  • 39 views
  • 01 Feb, 2022
  • 1 location
Featured trial
Parkinson's Disease

IS YOUR CURRENT PARKINSON’S MEDICATION NOT ENOUGH? Learn about a Parkinson’s Research Study at Wake Research in Raleigh, NC.

  • 9 views
  • 15 Feb, 2022
  • 1 location
Featured trial
The Orchestra Study: An 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease

The Orchestra Study will examine an investigational medication called UCB0599 in patients with early-stage Parkinson’s disease.   It will include patients with Parkinson’s disease (newly diagnosed or early-stage disease) from several countries across North America and Europe. As it is assessing disease and symptom progression over a long period of …

  • 0 views
  • 17 Mar, 2022
  • 1 location
Featured trial
A Study to Evaluate the Safety and Efficacy of IPX203 in Parkinson's Disease Patients With Motor Fluctuations

To evaluate the safety and efficacy of IPX203 (carbidopa and levodopa) extended-release capsules (IPX203 ER CD-LD) in comparison to immediate release (IR) CD-LD in the treatment of CD-LD-experienced subjects with Parkinson's disease (PD) who have motor fluctuations.  

illicit drug
  • 139 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Healthy Brain Aging Study

This study is looking for people who are 18 or older and have the early stages of various neurological conditions like Alzheimer’s, mild cognitive impairment, Lewy Body disease, or Parkinson’s disease.  The study is also looking for cognitively normal people over the age of 70, as a comparison.  Participants will …

Accepts healthy volunteers
cognitive impairment
mild cognitive impairment
  • 0 views
  • 24 Jan, 2022
  • 1 location
Featured trial
A clinical trial to evaluate the safety of NLRP3i (inhibitor of a protein called NLRP3) and how it affects the body and brain of people living with early-stage Parkinson’s disease.

This is a Phase 1b study conducted in the US, the UK, and the Netherlands and aiming to better understand the safety of an oral drug in a capsule form which includes a substance called NLRP3 inhibitor. The study aims to understand how the NLRP3 inhibitor affects the body and …

brain stimulation
cancer
levodopa
dementia
alpha-synuclein
  • 0 views
  • 16 Jun, 2022
  • 15 locations
Featured trial
Dementia with Lewy Bodies Consortium.

The purpose of this study is to collect clinical information, brain imaging scans, and biological samples from people that have dementia with Lewy bodies. This information will help researchers gain a better understanding of the biology behind LBD.

  • 26 views
  • 21 Jul, 2021
  • 1 location