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Found 500 clinical trials
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A Study to Evaluate the Safety Tolerability and Pharmacokinetics of BIIB094 in Adults With Parkinson's Disease

The primary objective of this study is to evaluate the safety and tolerability of single and multiple doses of BIIB094 administered via intrathecal (IT) injection to participants with Parkinson's Disease (PD). The secondary objective of this study is to evaluate the pharmacokinetic (PK) profile of BIIB094.The study is open for …

dyskinesia
  • 250 views
  • 25 May, 2021
  • 14 locations
featured
Use of a Non-Invasive Brainstem Neuromodulation Device to Improve Neurovascular Status in Parkinson's Disease

This study is a single-site, double-blinded, randomized clinical trial designed to elucidate mechanism(s) of action for symptomatic benefits observed in Parkinson's disease (PD)

  • 0 views
  • 16 Apr, 2021
  • 1 location
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Study in Parkinson Disease of Exercise

This study is a Phase 3 multi-site, randomized, evaluator-masked, study of endurance treadmill exercise on changes in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at 12 months among persons with early stage Parkinson disease. 370 participants will be randomly assigned to 2 groups: 1)60-65% HRmax …

  • 0 views
  • 04 Jun, 2021
  • 8 locations
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A Washington University research study is currently enrolling participants with Parkinson's disease.

The purpose of the research study is to learn if light therapy reduces sleep problems associated with Parkinson’s disease and improves quality of life. This study lasts 16 weeks. There will be five study visits. Each visit will last up to 4 hours. Up to $250.00 is provided for time …

poor sleep
sleep disorder
parkinson's disease
sleep study
sleep disturbances
  • 0 views
  • 16 Apr, 2021
  • 1 location
featured
Parkinson's disease

Roughly four million adults over 50 are diagnosed with Parkinson's disease. The progression of the disease is inevitable and it is estimated that those with the condition will need therapy within 1 to 3 years of diagnosis. There is currently no cure, but local physicians are seeking volunteers to evaluate …

  • 0 views
  • 16 Apr, 2021
  • 1 location
featured
Effect of LY3154207 on Cognition in Mild-to-Moderate Parkinson’s Disease Dementia (PDD)

Effect of LY3154207 on Cognition in Mild-to-Moderate Parkinson’s Disease Dementia (PDD)  

dementia
  • 830 views
  • 07 Nov, 2020
  • 1 location
featured
A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment

This study will evaluate the safety, tolerability, and potential effects on cognition of GRF6021, a plasma-derived product, administered as an intravenous (IV) infusion, to subjects with Parkinson's disease and cognitive impairment.  

cognitive impairment
dementia
movement disorder
  • 42 views
  • 24 Jan, 2020
  • 1 location
featured
Alpha-Synuclein Kinetics

Alpha-synuclein (a-syn) is a protein and a major component of Parkinson’s Disease (PD). The purpose of this study is to determine the kinetics (half-life or how quickly a-syn is cleared from the body), we will use 3 proven approaches to determine this. 10 days of oral-labeling followed by 5 subsequent LPs …

alpha-synuclein
  • 40 views
  • 24 Jan, 2020
  • 1 location
featured
Computational modeling of 60 Hz subthalamic nucleus deep brain stimulation for gait disorder in Parkinson's disease

The goal of this research is to further our understanding and application of deep brain stimulation in Parkinson's patients with gait disorder.  

levodopa
brain stimulation
  • 13 views
  • 11 Jun, 2020
  • 1 location
featured
Parkinson’s Disease (Observational Study)

Do you or a loved one have Parkinson’s disease? Learn more about an observational clinical research study for individuals who have, or are at risk for, Parkinson’s disease.  

  • 6 views
  • 23 Nov, 2020
  • 1 location