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Found 514 clinical trials
Featured trial
Fox Insight - Online Parkinson's Health and Genetic Study

Fox Insight is an online study gathering health information from tens of thousands of people with and without Parkinson’s disease.  Study participation does not require any travel and all you need is an internet connection to start today at www.foxinsight.orgFox Insight volunteers are invited to take part in virtual ‘study visits’ …

Online studies
  • 597 views
  • 10 Dec, 2021
  • 1 location
  • Online study
Featured trial
Patient Experience Interviews to Inform a Digital Assessment of Parkinson’s Disease

F.Hoffmann-La Roche Ltd (“Roche”) has developed a set of tests for individuals living with Parkinson’s disease. The tests are completed using a smartphone application (app) and assess a person's motor behavior including movement of their hands, balancing, walking and turning around. The purpose of this study is to learn about …

Online studies
  • 6 views
  • 02 May, 2022
  • 1 location
  • Online study
Featured trial
Parkinson Progression Marker Initiative Online (PPMI Online)

Parkinson Progression Marker Initiative Online (PPMI online) is part of the broader Parkinson’s Progression Marker Initiative aimed at better understanding who gets Parkinson’s disease and why. PPMI online is a study collecting participant reported demographic and health information online from people with and without Parkinson’s disease. Once in the study, …

Accepts healthy volunteers
Online studies
  • 45 views
  • 30 Mar, 2022
  • 1 location
  • Online study
Featured trial
A Study to Evaluate the Safety Tolerability and Pharmacokinetics of BIIB094 in Adults With Parkinson's Disease

The primary objective of this study is to evaluate the safety and tolerability of single and multiple doses of BIIB094 administered via intrathecal (IT) injection to participants with Parkinson's Disease (PD). The secondary objective of this study is to evaluate the pharmacokinetic (PK) profile of BIIB094.The study is open for …

dyskinesia
  • 807 views
  • 18 May, 2022
  • 14 locations
Featured trial
A Study to Assess the Safety of BIIB122 Tablets and if it Can Slow the Worsening of Early-Stage Parkinson's Disease in Participants Between the Ages of 30 and 80

In this study, researchers will learn more about a study drug called BIIB122 in participants with early-stage Parkinson's disease (PD). In this study: Participants will take 225 milligrams (mg) of BIIB122 or a placebo as tablets by mouth. A placebo looks like the study drug but has no real medicine …

movement disorder
hoehn and yahr scale
  • 0 views
  • 25 May, 2022
  • 1 location
Featured trial
PROSEEK: A Phase 2 Study In Early Parkinson's Disease Patients Evaluating The Safety And Efficacy Of Abl Tyrosine Kinase Inhibition Using K0706

This study consists of 2 parts. Part 1 of the study is conducted to evaluate the efficacy, safety, and tolerability of two doses of K0706 compared to placebo in subjects with early Parkinson's Disease who are not receiving dopaminergic therapy. Part 2 is an optional long term extension study for …

early parkinson's
  • 0 views
  • 03 May, 2022
  • 70 locations
Featured trial
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease (PADOVA)

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.

SPECT Scan
bradykinesia
dopamine
dopamine transporter
tremor
  • 99 views
  • 09 May, 2022
  • 109 locations
Featured trial
Use of a Non-Invasive Brainstem Neuromodulation Device to Improve Neurovascular Status in Parkinson's Disease

This study is a single-site, double-blinded, randomized clinical trial designed to elucidate mechanism(s) of action for symptomatic benefits observed in Parkinson's disease (PD)

dopamine
motor symptoms
  • 0 views
  • 18 May, 2022
  • 1 location
Featured trial
Study in Parkinson Disease of Exercise (SPARX3)

This study is a Phase 3 multi-site, randomized, evaluator-masked, study of endurance treadmill exercise on changes in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at 12 months among persons with early stage Parkinson disease. 370 participants will be randomly assigned to 2 groups: 1)60-65% HRmax …

movement disorder
SPECT Scan
datscan
  • 146 views
  • 25 Apr, 2022
  • 25 locations
Featured trial
Ketamine for the Treatment of Depression in Parkinson's Disease (KET-PD)

The main purpose of this study is to examine the efficacy and safety of a repeated dosing ketamine infusion paradigm compared to placebo in individuals with PD.

hoehn and yahr scale
depression
depressive disorder
depressed mood
ketamine
  • 6 views
  • 12 May, 2022
  • 1 location