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Found 506 clinical trials
Featured trial
Fox Insight - Online Parkinson's Health and Genetic Study

Fox Insight is an online study gathering health information from tens of thousands of people with and without Parkinson’s disease.  Study participation does not require any travel and all you need is an internet connection to start today at www.foxinsight.orgFox Insight volunteers are invited to take part in virtual ‘study visits’ …

Online studies
  • 1335 views
  • 10 Dec, 2021
  • 1 location
  • Online study
Featured trial
Parkinson's Progression Markers Initiative Online (PPMI Online)

Parkinson's Progression Markers Initiative Online (PPMI online) is part of the broader Parkinson’s Progression Markers Initiative aimed at better understanding who gets Parkinson’s disease and why. PPMI online is a study collecting participant reported demographic and health information online from people with and without Parkinson’s disease. Once in the study, …

Online studies
Accepts healthy volunteers
  • 162 views
  • 14 Sep, 2022
  • 1 location
  • Online study
Featured trial
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease (PADOVA)

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.

SPECT Scan
tremor
dopamine transporter
parkinsonism
bradykinesia
  • 160 views
  • 28 Oct, 2022
  • 104 locations
Featured trial
The Orchestra Study: An 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease

The Orchestra Study (study number PD0053) is a clinical research study for people with early-stage Parkinson’s disease (<2 years). The aim of the study is to find out whether an investigational medication known as UCB0599 can slow the progression of Parkinson’s disease and whether it is efficacious and well tolerated (which means …

SPECT Scan
tremor
motor symptoms
dopamine transporter
movement disorder
  • 349 views
  • 11 Nov, 2022
  • 116 locations
Featured trial
A Study to Assess the Safety of BIIB122 Tablets and if it Can Slow the Worsening of Early-Stage Parkinson's Disease in Participants Between the Ages of 30 and 80 (LUMA)

In this study, researchers will learn more about a study drug called BIIB122 in participants with early-stage Parkinson's disease (PD). In this study: Participants will take 225 milligrams (mg) of BIIB122 or a placebo as tablets by mouth. A placebo looks like the study drug but has no real medicine …

movement disorder
hoehn and yahr scale
  • 9 views
  • 17 Nov, 2022
  • 6 locations
Featured trial
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BIIB094 in Adults With Parkinson's Disease (REASON) (REASON)

The primary objective of this study is to evaluate the safety and tolerability of single and multiple doses of BIIB094 administered via intrathecal (IT) injection to participants with Parkinson's Disease (PD). The secondary objective of this study is to evaluate the pharmacokinetic (PK) profile of BIIB094.The study is open for …

dyskinesia
  • 844 views
  • 16 Nov, 2022
  • 16 locations
Featured trial
PROSEEK: A Phase 2 Study In Early Parkinson's Disease Patients Evaluating The Safety And Efficacy Of Abl Tyrosine Kinase Inhibition Using K0706

This study consists of 2 parts. Part 1 of the study is conducted to evaluate the efficacy, safety, and tolerability of two doses of K0706 compared to placebo in subjects with early Parkinson's Disease who are not receiving dopaminergic therapy. Part 2 is an optional long term extension study for …

early parkinson's
  • 43 views
  • 17 Nov, 2022
  • 72 locations
Featured trial
The Orchestra Study: An 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease

The Orchestra Study will examine an investigational medication called UCB0599 in patients with early-stage Parkinson’s disease .   It will include patients with Parkinson’s disease (newly diagnosed or early-stage disease) from several countries across North America and Europe. As it is assessing disease and symptom progression over a long period …

  • 0 views
  • 11 Nov, 2022
  • 41 locations
Featured trial
STEM-Parkinson's Disease

This is a double-blinded, controlled, randomized clinical trial (RCT) to establish the safety and efficacy of a non-invasive neuromodulation device for treating symptoms associated with Parkinson's disease.

motor symptoms
dopamine
  • 15 views
  • 11 Nov, 2022
  • 16 locations
Featured trial
Study in Parkinson Disease of Exercise (SPARX3)

This study is a Phase 3 multi-site, randomized, evaluator-masked, study of endurance treadmill exercise on changes in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at 12 months among persons with early stage Parkinson disease. 370 participants will be randomly assigned to 2 groups: 1)60-65% HRmax …

SPECT Scan
movement disorder
datscan
  • 169 views
  • 07 Oct, 2022
  • 26 locations