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Found 572 clinical trials
Featured trial
A Study to Evaluate the Safety Tolerability and Pharmacokinetics of BIIB094 in Adults With Parkinson's Disease

Parkinson's Disease (PD). The secondary objective of this study is to evaluate the pharmacokinetic (PK) profile of BIIB094.The study is open for PD patients with verified presence or absence of mutations in the

dyskinesia
  • 831 views
  • 23 Sep, 2022
  • 16 locations
Featured trial
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease (PADOVA)

Parkinson's Disease (PD) who are on stable symptomatic PD medication.

bradykinesia
tremor
dopamine transporter
SPECT Scan
dopamine
  • 155 views
  • 27 Sep, 2022
  • 104 locations
Featured trial
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of BIIB122/DNL151 in Participants With Parkinson's Disease and Pathogenic LRRK2 Variants

In this study, researchers will learn more about a study drug called BIIB122 in participants with early-stage Parkinson's disease (PD). The study will focus on participants with a specific

hoehn and yahr scale
depression
motor symptoms
movement disorder
  • 0 views
  • 20 Sep, 2022
  • 2 locations
Featured trial
PROSEEK: A Phase 2 Study In Early Parkinson's Disease Patients Evaluating The Safety And Efficacy Of Abl Tyrosine Kinase Inhibition Using K0706

This study consists of 2 parts. Part 1 of the study is conducted to evaluate the efficacy, safety, and tolerability of two doses of K0706 compared to placebo in subjects with early Parkinson's

early parkinson's
  • 19 views
  • 21 Sep, 2022
  • 72 locations
Featured trial
A Study to Assess the Safety of BIIB122 Tablets and if it Can Slow the Worsening of Early-Stage Parkinson's Disease in Participants Between the Ages of 30 and 80

In this study, researchers will learn more about a study drug called BIIB122 in participants with early-stage Parkinson's disease (PD). In this study: Participants will take

hoehn and yahr scale
movement disorder
  • 3 views
  • 14 Sep, 2022
  • 4 locations
Featured trial
Ketamine for the Treatment of Depression in Parkinson's Disease (KET-PD) (KET-PD)

The main purpose of this study is to examine the efficacy and safety of a repeated dosing ketamine infusion paradigm compared to placebo in individuals with PD. A subset of participants in each arm will undergo baseline and post-treatment PET and fMRI scans, to examine whether changes in synaptic density …

depressive disorder
depressed mood
ketamine
hoehn and yahr scale
depression
  • 36 views
  • 17 Sep, 2022
  • 1 location
Featured trial
Using Time Varying Non-Invasive Neuromodulation to Improve Neurovascular Status in Parkinson's Disease

This study is a single-site, double-blinded, randomized clinical trial designed to elucidate mechanism(s) of action for symptomatic benefits observed in Parkinson's disease (PD)

motor symptoms
dopamine
  • 17 views
  • 23 Sep, 2022
  • 1 location
Featured trial
Study in Parkinson Disease of Exercise Phase 3 Clinical Trial: SPARX3 (SPARX3)

primary objective is to test whether the progression of the signs of Parkinson's disease is attenuated at 12 months in among persons who have not initiated medication for Parkinson Disease (PD) when they

datscan
SPECT Scan
movement disorder
  • 166 views
  • 21 Sep, 2022
  • 26 locations
Featured trial
The Orchestra Study: An 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease

The Orchestra Study will examine an investigational medication called UCB0599 in patients with early-stage Parkinson’s disease.   It will include patients with Parkinson’s disease (newly diagnosed or early-stage disease) from several countries across North America and Europe. As it is assessing disease and symptom progression over a long period of …

  • 0 views
  • 20 Sep, 2022
  • 26 locations
Featured trial
Parkinson's Disease

IS YOUR CURRENT PARKINSON’S MEDICATION NOT ENOUGH? Learn about a Parkinson’s Research Study at Wake Research in Raleigh, NC.

  • 9 views
  • 15 Feb, 2022
  • 1 location