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Found 45 clinical trials
Doxycycline Injection of Cutaneous Schwannoma in Neurofibromatosis Type 2

In this research study the investigators want to learn more about an alternate, local treatment for skin schwannomas. Specifically, local doxycycline intra-tumoral injection will be performed as a potential treatment for NF2-related skin schwannomas, ultimately reducing the risks and costs associated with standard surgical removal of such skin tumors if …

  • 0 views
  • 10 Oct, 2022
  • 1 location
Spinal Cord Stimulation in the Treatment of Chronic, Intractable Pain Using the Nalu™ Neurostimulation System (nPower™-US)

The Nalu Neurostimulation System is capable of delivering multiple therapy options to address patient needs. The study will confirm the efficacy, safety, comfort and compliance with the Nalu Neurostimulation System in adult subjects with chronic pain in the legs and back. Patients who have been diagnosed with failed back surgery …

intractable pain
failed back surgery syndrome
back surgery
spinal cord
chronic pain
  • 111 views
  • 21 Mar, 2022
  • 8 locations
Burst-Deep Brain Stimulation of the Thalamus for Neuropathic Facial Pain and Central Poststroke Pain: a Prospective, Randomized Cross-over Feasibility Trial

Central post-stroke pain (CPSP) is a neuropathic pain syndrome and one of the major sequelae after ischemic or hemorrhagic cerebral stroke. Recently, a modified stimulation paradigm has been developed in the field of spinal cord stimulation (SCS) for a variety of neuropathic pain disorders. To date, this stimulation paradigm has …

anesthesia
neuralgia
local anesthesia
spinal cord
antidepressants
  • 0 views
  • 23 Oct, 2022
  • 1 location
Coordinated Reset Spinal Cord Stimulation

The goal of this study is to evaluate whether a new spinal cord stimulation paradigm, called Coordinate Reset (CR) Stimulation, can provide equivalent or better pain relief with reduced energy requirements. The investigators will test this new stimulation paradigm in patients who are already undergoing spinal cord stimulation surgery. The …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Efficacy of Ultrasound-Guided Hydrodissection in Patients With Carpal Tunnel Syndrome

The aim of our study is to determine the effectiveness of US-guided hydrodissection of the median nerve in different contents and volumes in patients diagnosed with mild to moderate carpal tunnel syndrome.

5% dextrose
electrophysiological studies
numbness
  • 0 views
  • 16 Oct, 2022
  • 1 location
Topical Menthol Application in Chemotherapy-Related Peripheral Neuropathy in Patients With Breast Cancer

Peripheral neuropathy resulting from chemotherapy is a problem that concerns not only the individual but also their relatives and all healthcare personnel responsible for care. Studies to be carried out in this area are important in terms of providing evidence for nurses' practices and supporting the individual by alleviating the …

cancer
paclitaxel
  • 0 views
  • 04 Oct, 2022
  • 1 location
Parathyroid Allotransplantation in Medically Refractory Hypoparathyroidism (PATH)

Options for treatment of severe, refractory hypocalcemia are limited for the thousands of patients in the United States who suffer from hypoparathyroidism. Parathyroid allotransplantation is an emerging treatment that provides hope for these individuals. Currently, this therapy has only been successfully provided by a few centers in the world. In …

calcium
hypocalcemia
  • 0 views
  • 10 Apr, 2022
  • 1 location
Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over study testing two different classes of anti arrhythmic drugs (AADs). This pilot and feasibility study will provide preliminary data for a larger study in which the investigators will …

flecainide
sotalol
fibrillation
antiarrhythmic drug
  • 319 views
  • 08 Jul, 2022
  • 1 location
Pulsed Radiofrequency of Suprascapular Nerve and Shoulder Joint for Chronic Shoulder Pain

Background: The suprascapular nerve block is frequently used to treat chronic shoulder pain. The nerve blockade provides probably only a short-term relief, and more compelling approaches have been investigated. Pulsed radiofrequency stimulation of suprascapular nerve has been reported as safe and reliable method for pain treatment. However, formal efficacy study …

  • 0 views
  • 10 Feb, 2021
  • 1 location
Arthroscopic Versus Open Brostrom for Ankle Instability

Background: Ankle sprains are among the most prevalent lesions in primary care. A substantial number of these ligament lesions will develop ankle instability and require a surgical procedure. The Brostrom-Gould technique is the standard surgical approach for this condition, providing excellent results over the years. Thru the last decades, the …

anterior drawer test
soft tissue injury
  • 2 views
  • 15 Feb, 2022
  • 1 location