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Found 41 clinical trials
Twice Against Thrice-weekly Hemodialysis (TATH)

Hemodialysis is the most worldwide prescribed renal replacement therapy for patients with end-stage renal disease. The frequency of sessions per week remains a debatable issue. In the majority of developed Western and Asian countries, patients on chronic hemodialysis are undergoing three dialysis sessions weekly. In developing countries and some developed …

chronic hemodialysis
renal replacement therapy
chronic renal failure
  • 26 Feb, 2022
  • 1 location
The Effect of Calcium Intake on Calcium and Bone Metabolism During Load Carriage in Women (En-Bone)

calcium supplementation before load carriage exercise will attenuate the decline in serum ionised calcium and increase in parathyroid hormone and bone resorption.

Accepts healthy volunteers
  • 11 May, 2022
  • 1 location
PTH Analog Type II Odontoid Fracture

cervical spine CT scan. This will be a pilot efficacy trial to compare treatment of odontoid fractures with 8 weeks of treatment with a parathyroid hormone analog (PTH) analog (abaloparatide) + hard collar

  • 12 Jul, 2022
  • 1 location
Total Parathyroidectomy With Autotransplantation Versus Total Parathyroidectomy Alone for Secondary Hyperparathyroidism

Total parathyroidectomy with autotransplantation (TPTX+AT) and Total parathyr- oidectomy alone (TPTX) are the common surgical procedures.The purpose of the study was to compare the long-term benefits of surgery between the two groups.

  • 04 Oct, 2021
Novel Combination Therapy for Osteoporosis in Men (Osteo-Men)

Osteoporotic fractures are a key health problem in older men. Although there are drugs approved to treat osteoporosis in men [bisphosphonates, denosumab, and teriparatide (TPTD) or PTH(1-34)], there is a lack of knowledge on how to use them effectively. TPTD is a potent bone anabolic drug, meaning that it builds …

  • 26 Feb, 2022
  • 1 location
A Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

This is a Phase 3 Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

secondary hyperparathyroidism
chronic kidney disease
renal disease
  • 26 Jul, 2022
  • 37 locations
Vitamin D Supplementation in the Armed Forces (D_SAF)

The study will comprise of an original investigation that will take the form of a prospective intervention (two matched groups) study. Condition-1 will be a vitamin D supplementation group (50.000 IU every two months), and Condition-2 will be a placebo supplementation group. The primary research aim of this project is …

Accepts healthy volunteers
stress fracture
soft tissue infection
vitamin d supplementation
  • 08 Feb, 2022
  • 1 location
Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic Acid

Osteogenesis imperfecta (OI) is an inherited skeletal disorder characterised by increased risk of fragility fractures. Bisphosphonates are frequently prescribed for adult patients with OI with the aim of preventing fractures but the evidence base for efficacy is poor. Recent evidence suggests that the bone anabolic agent teriparatide (TPTD) increases bone …

bone mineral density
care adult
parathyroid hormone
  • 22 Jan, 2021
  • 25 locations
Treatment of Adynamic Bone Disorder With Parathyroid Hormone in Chronic Kidney Disease

recombinant human parathyroid hormone for treatment of adynamic bone disorder in patients with chronic kidney disease.

parathyroid hormone
  • 05 Jun, 2021
  • 3 locations
Study of Teriparatide in Stress Fracture Healing

Investigation into the use of teriparatide in the treatment of stress fractures. Primary outcome is healing on MRI, secondary outcomes are pain, time spent in rehabilitation and future stress fractures. This study will help the investigators understand how to treat stress fractures in the future.

  • 26 Jan, 2021
  • 1 location