Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 44 clinical trials
DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & Other Malignancies

This is first in human study of DFF332, a small molecule that targets a protein called HIF2α. By acting on HIF2α, DFF332 may be able to stop the growth of certain types of cancer. DFF332 will be tested at different doses as single agent and in combination with Everolimus (RAD001, …

clear cell renal cell carcinoma
vegf
rad001
everolimus
cancer
  • 16 views
  • 30 Jun, 2022
  • 10 locations
Multicenter Pheochromocytoma and Paraganglioma Evaluation

Target population: Patients with (1) newly diagnosed or (2) past history of pheochromocytomas and paragangliomas (PPGL) or (3) carrier of genetic mutations in known PPGL susceptibility

special care
adrenal pheochromocytoma
paraganglioma
pheochromocytoma
  • 36 views
  • 24 Jan, 2021
  • 1 location
A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paraganglioma

Pheochromocytoma/Paraganglioma.

malignant pheochromocytoma
metastatic disease
pheochromocytoma
therapeutic vaccine
metastasis
  • 14 views
  • 17 Dec, 2021
  • 13 locations
Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With GEP-NETs and PPGLs

This is a multicenter, open-label, single-arm study to evaluate the safety and dosimetry of Lutathera in adolescent patients 12 to <18 years old with somatostatin receptor positive GEP-NETs and PPGLs. The study will enroll at least 8 patients in the GEP-NET cohort and as many adolescents with PPGL as possible …

somatostatin
dotatate
metastatic disease
  • 0 views
  • 15 Jul, 2022
  • 11 locations
Diagnosis of Pheochromocytoma

The goal of this study is to develop better methods of diagnosis, localization, and treatment for pheochromocytomas. These tumors, which usually arise from the adrenal glands, are often difficult to detect with current methods. Pheochromocytomas release chemicals called catecholamines, causing high blood pressure. Undetected, the tumors can lead to severe …

ct scan
computed tomography
clonidine
positron emission tomography
anesthesia
  • 20 views
  • 28 Jul, 2022
  • 1 location
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), or Von Hippel-Lindau (VHL) Disease-Associated Tumors (MK-6482-015)

This is a study to evaluate the efficacy and safety of Belzutifan monotherapy in participants with advanced pheochromocytoma/paraganglioma (PPGL), pancreatic neuroendocrine tumor (pNET) or von

  • 0 views
  • 20 Jul, 2022
  • 41 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

, malignant (closed to accrual) Paraganglioma (closed to accrual 11/29/2018) Carcinomas of pituitary gland, thyroid gland parathyroid gland and adrenal cortex (closed to accrual)

ct scan
parathyroid
lymphoma
human immunodeficiency virus
beta-hcg
  • 6637 views
  • 10 Aug, 2022
  • 752 locations
18F-DOPA II - PET Imaging Optimization

A single centre non-randomized, non-blinded phase III prospective cohort study of 18F-DOPA PET/CT imaging in specific patient populations: Pediatric patients (less than 18 years old) with congenital hyperinsulinism. Pediatric patients (less than 18 years old) with neuroblastoma. Pediatric (less than 18 years old) or Adult patients (18 or older) with …

parkinson's disease
dementia
dopa
  • 8 views
  • 03 May, 2022
  • 1 location
LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA)

The objectives of this study are: To assess the efficacy of lanreotide given every 4 weeks in participants with advanced or metastatic paraganglioma/ pheochromocytoma. To

metastatic disease
chromogranin a
adrenal pheochromocytoma
catecholamines
pheochromocytoma
  • 0 views
  • 24 Nov, 2021
  • 2 locations
Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

Background Pheochromocytoma and paraganglioma are rare tumors. They usually form inside and near the adrenal gland or in the neck region. Not all these tumors can

prrt
lutathera
positron emission tomography
oophorectomy
measurable disease
  • 6 views
  • 27 Jul, 2022
  • 1 location