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Found 323 clinical trials
Von Hippel-Lindau (VHL): Clinical Manifestations Diagnosis Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

We will investigate the clinical manifestations and molecular genetic defects of heritable urologic malignant disorders. Families with urologic malignancy with known or suspected genetic basis will be enrolled. Affected individuals or individuals suspected of having a germline urologic malignant disorder will undergo periodic clinical assessment and genetic analyses for the …

sarcoma
cancer
kidney cancer
clear cell renal cell carcinoma
von hippel-lindau syndrome
  • 447 views
  • 01 Apr, 2021
  • 1 location
Acotec DCB Post Market Clinical Follow-up

All-comers, prospective, multi-center, single-arm, non-interventional post market clinical follow-up (PMCF) Cohort 1 - Claudicants: Rutherford Clinical Category (RCC) 2-3 Cohort 2 - Critical

paclitaxel
transluminal angioplasty
limb ischemia
critical limb ischaemia
stenosis
  • 0 views
  • 04 Mar, 2021
  • 7 locations
Study of Kidney Tumors in Younger Patients

This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.

biomarker analysis
nephroblastoma
cancer
papillary renal cell carcinoma
kidney tumor
  • 675 views
  • 27 Jan, 2021
  • 105 locations
Development of Urologic Registry for Personalized Medicine in Patients With Urological Malignancy by Analyzing Circulating Tumor DNA

Urological malignancies such as prostate cancer and renal cell cancer in Korean population have been increased due to the aged population and the westernized lifestyles. With the advancement of

bladder cancer
cancer
bladder tumor
kidney cancer
  • 0 views
  • 23 Jan, 2021
  • 1 location
Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

>Chondromyxoid fibroma Chordoma Clear cell renal carcinoma Clear Cell Sarcoma Clear cell sarcoma of kidney Conventional chordoma Dedifferentiated

cns tumor
solid tumor
cancer
  • 0 views
  • 08 Apr, 2021
  • 1 location
MyVHL: Patient Natural History Study

MyVHL is a multi-patient database which helps researchers identify patterns across VHL patients. MyVHL provides you -and researchers -with more complete information about VHL, like how your lifestyle, medications, and other factors impact the disease and quality of life. These insights help you better understand the condition and help researchers …

tumor growth
  • 29 views
  • 25 Jan, 2021
  • 1 location
The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)

The PIONEER Initiative stands for Precision Insights On N-of-1 Ex vivo Effectiveness Research. The PIONEER Initiative is designed to provide access to functional precision medicine to any cancer patient with any tumor at any medical facility. Tumor tissue is saved at time of biopsy or surgery in multiple formats, including …

cancer
drug screening
precision medicine
  • 12 views
  • 27 Jan, 2021
  • 1 location
Long Term Follow-up of Mesothelioma Patients and Their Family Members With Germline Mutations in BAP1 and Other Genes

Background -A gene provides instructions to the body. Mutated genes can sometimes cause cancer. Germline mutations are those people are born with. These mutations in the BAP1 gene can cause mesothelioma and other cancers. Researchers want to study people with germline mutations of BAP1 and other genes known to cause …

BAP1
blood test
skin lesions
cancer
  • 5 views
  • 06 May, 2021
  • 1 location
Evaluation of Urinary Exosomes Presence From Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma is diagnosed by imaging, sometimes associated with biopsy. This diagnosis is expensive, invasive and sometimes late. The development of a simple biological test

tumor markers
cancer
clear cell renal cell carcinoma
nephrectomy
carcinoma
  • 0 views
  • 30 Jan, 2021
  • 1 location
Renal Cell Carcinoma Microenvironment Discovery Project

This study will obtain tumor samples from nephrectomy specimens in a multi-regional fashion and subject them to integrated genomics, pathological and radiological assessment. The goal is to better understand the the molecular basis for how various cells within the tumor microenvironment act in a coordinated manner to facilitate tumor progression …

nephrectomy
carcinoma
metastasis
  • 3 views
  • 25 Jan, 2021
  • 1 location