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Found 100 clinical trials
LTOT in COPD Patients With Moderate Chronic Hypoxemia and Chronic Heart Failure

In patients with both COPD and CHF, moderate chronic hypoxemia is caused by a combination of intrapulmonary and extrapulmonary factors. The hypothesis of this study is that adequate medical therapy for both conditions can correct the moderate hypoxemia by improving the underlying mechanisms without the need of LTOT. If this …

COPD
pulmonary disease
medical therapy
  • 31 views
  • 07 Nov, 2020
  • 1 location
High Flow Nasal Cannula With Noninvasive Ventilation

This is a prospective, randomized, unblinded trial of trauma patients in the ICU who are identified as being at a high risk to develop acute respiratory failure. We hope that this study will help the study team to identify how best to use a more aggressive respiratory treatment strategy in …

  • 0 views
  • 27 Jan, 2021
  • 1 location
The Relationship Between Oxygen Reserve Index and PaO2

partial pressure of arterial blood oxygen (PaO2) in children.

  • 2 views
  • 25 Jan, 2021
Evaluation of the Effect of Different Doses Dexmedetomidine Infusion on Lung Mechanics and Oxygenation in Obese Patients

The objective of this study is to evaluate the effect of different doses of dexmedetomidine infusion intraoperative on lung mechanics and oxygenation regarding PaO2/Fraction of inspired oxygen

  • 0 views
  • 04 Feb, 2021
  • 1 location
Lowering PEEP: Weaning From High PEEP Setting

sum of two kind of venus-admixured. As it is known from classical physiology, the effects of FiO2 variations on PaO2 are deeply different depending on the type of venous admixures. In the case of a

positive end expiratory pressure
pao2
FIO2
  • 0 views
  • 26 Jan, 2021
  • 1 location
Comparison of High Flow Nasal Cannula (HFNC) Face-mask Non-Invasive Ventilation (NIV) & Helmet NIV in COVID-19 ARDS Patients

respiratory rate (RR) more than 30/min or oxygen saturation (SpO2) less than 90% or PaO2/FiO2 ratio less than 300 despite standard oxygen therapy by face mask (<15 L/min) who present to Royal hospital or

  • 0 views
  • 28 Jan, 2021
  • 1 location
Dexamethasone and the Prevention of Post-Extubation Airway Obstruction in Adults

Laryngotracheal injury related to intubation may cause narrowing of the airway due to edema of the glottis. Post-extubation airway frequently necessitating re-intubation and resulting in the prolongation of intensive care. Factors correlating with the development of post-extubation stridor include age, female gender, an elevated Acute Physiologic and Chronic Health Evaluation …

systolic blood pressure
intubation
pao2
oxygen saturation
  • 0 views
  • 07 Nov, 2020
  • 1 location
CPAP in Liver Transplant

The purpose of this study is to determine the effectiveness of continuous positive airway pressure compared to standard treatment in preventing the need for intubation and mechanical ventilation in patients who develop acute hypoxemia after liver transplant. Hypoxemia complicates the recovery of 30-50 % of patients after abdominal surgery; endotracheal …

  • 4 views
  • 07 Nov, 2020
  • 1 location
Allocetra-OTS in COVID-19 Phase II

This is a multi-center, open-label study evaluating the safety of Allocetra-OTS, in up to 24 subjects with severe COVID-19 and respiratory dysfunction. Subjects, who will be identified as suffering from COVID-19, will be recruited. After signing an informed consent by the patient and, within 24+6 hours following the time of …

  • 0 views
  • 25 Jan, 2021
  • 3 locations
Therapeutic Plasma Exchange Rituximab and IV Ig for Severe Acute Exacerbation of IPF Admitted in ICU

Idiopathic pulmonary fibrosis (IPF) is a fibroproliferative, irreversible disease of unknown cause, occurring mainly in patients older than 50. IPF is a rare but fatal lung disease, with an estimated prevalence of 14 to 28/100000 and a median survival time of 3 years. Acute exacerbation of IPF (AE-IPF) is a …

  • 9 views
  • 25 Jan, 2021
  • 2 locations