Found 55 clinical trials
Speeding the Weaning up: Aggressive Screening Criteria and Higher Minimal Ventilatory Settings. (SPEED-UP)
: This is a multicenter randomized open trial with 4 arms. Screening with PaO2/FiO2 > 180 and PEEP ≤ 10cm H2O; SBT with "HIGH minimal ventilator settings" (PS 8 + PEEP 5 cm H2O).
- 0 views
- 04 Oct, 2022
- 1 location
High Flow Nasal Cannula With Noninvasive Ventilation
This is a prospective, randomized, unblinded trial of trauma patients in the ICU who are identified as being at a high risk to develop acute respiratory failure. We hope that this study will help the study team to identify how best to use a more aggressive respiratory treatment strategy in …
- 0 views
- 26 Apr, 2022
- 1 location
The Relationship Between Oxygen Reserve Index and PaO2
partial pressure of arterial blood oxygen (PaO2) in children.
- 2 views
- 12 May, 2022
- 1 location
NanoMn®_COVID-19 A Prospective, Multicenter, Randomized, Placebo-controlled, Parallel-group, Double-blind Trial to Evaluate the Clinical Efficacy of NanoManganese® on Top of Standard of Care, in Adult Patients With Moderate to Severe Coronavirus Disease 2019 (COVID-19)
>Placebo + SoC (N=30) NanoManganese® + SoC (N=90) Patients will be treated and followed-up for 10 days: Arterial oxygen partial pressure (PaO2) will be measured at
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- 04 Oct, 2022
- 1 location
Nurses-driven, Capnography-guided Protocol Weaning From the Mechanical Ventilation at Bedside: A Feasibility Study (NURSES-WEAN)
following criteria are present: PEEP ≤ 8 cmH2O, PaO2/FiO2 ratio ≥150 (mmHg) or SaO2 ≥ 90% with FiO2 ≤ 0.5. The final criterion for study entry is successful completion of a 30-min spontaneous breathing test
- 0 views
- 17 Jun, 2022
- 1 location
Flow Rates of High-flow Nasal Cannula and Extubation Outcome
This is a single-center, open-label, randomized controlled trial to evaluate the effect of high-flow nasal cannula with a flow rate of 60 L/min versus 40 L/min after planned extubationon on a composite outcome of reintubation and use of NIV.
- 0 views
- 18 Jun, 2022
- 1 location
Use of Extracorporeal CO2 Removal in Case of Moderate to Severe Acute Respiratory Distress Syndrome to Apply an Ultraprotective Mechanical Ventilation Strategy (ECCO2R)
The extracorporeal CO2 removal (ECCO2R) has been recently proposed in case of Acute Respiratory Distress Syndrome (ARDS) in order to reduce pulmonary injuries induced by the mechanical ventilation. A reducing of tidal volume and/or respiratory rate is thus expected using this extracorporeal respiratory support. However, most of existing devices of …
- 0 views
- 21 Oct, 2022
- 1 location
Hyperpolarized MRI of Lung Transplants
Chronic complications such as chronic lung allograft dysfunction (CLAD) remain the leading cause of death and the primary limitation to long-term survival for lung transplant recipients. CT is currently use for longitudinal assessment in the pediatric population with lung transplant. However, it uses radiation that has been related to increase …
- 0 views
- 10 Jul, 2022
- 1 location
Improving Tissue Oxygenation in Breast Reconstruction Surgery
Breast reconstruction is an integral part of breast cancer care. There are two main types of breast reconstruction: alloplastic (using implants), and autologous (using patient's tissue). The latter creates a more natural breast mound, and avoids long-term concerns requiring surgical re-intervention associated with implant-based surgery. The deep inferior epigastric perforator …
- 15 views
- 21 Apr, 2022
- 2 locations
Conservative Versus Conventional Oxygen Administration in Critically Ill Patients
oxygen partial pressure (PaO2) considered harmful, or the dangerous duration of hyperoxia, is not determined yet as there are no clinical trials on humans that evaluate the appropriate percentage of
- 2 views
- 21 Feb, 2022
- 1 location