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Found 151 clinical trials
Influence Factors of PD-1 Therapeutic Efficacy in Advanced Pancreatic Cancer

The early diagnosis rate of pancreatic cancer is low and most patients rely on palliative chemotherapy. However, the clinical benefit and objective response rate (ORR) of patients with first-line chemotherapy are low. Therefore,it is essential to develop new therapies to improve the survival of patients with pancreatic cancer.

  • 0 views
  • 24 Mar, 2022
  • 1 location
PRedictiOn Algorithms for the DeTECTion of Early Stage Pancreatic Cancer

Conduct a prospective study to assess the accuracy of a pancreatic cancer risk prediction model.

  • 0 views
  • 23 May, 2021
  • 1 location
Ablation of Unresectable Locally Advanced Pancreatic Cancer With Irreversible Electroporation (IRE) System

Patients with pancreatic ductal adenocarcinoma will be screened by pancreatic protocol cross-sectional imaging to see if they have locally advanced unresectable pancreatic ductal adenocarcinoma

metastasis
tumor markers
adenocarcinoma
cancer chemotherapy
pancreatic ductal adenocarcinoma
  • 14 views
  • 12 Feb, 2022
  • 1 location
Discovery of Soluble Biomarkers for Pancreatic Cancer Using Innovative All-Patient Inclusive Methodology

Pancreatic ductal adenocarcinoma (PDAC) remains among cancers with a very poor prognosis (1-year survival <20%). Endoscopic ultrasound with fine needle aspiration (EUS/FNA) is the common

breast ductal carcinoma
pdac
fine needle aspiration
fine needle biopsy
adenocarcinoma
  • 0 views
  • 28 Oct, 2021
  • 1 location
The Role of MicroRNA in the Diagnosis Prognosis and Response to Treatment in Pancreatic Cancer

Aberrant miRNA production has been linked to a wide range of human cancers and shown to play important roles in their genesis and growth. These miRNA can be detected in the blood and tumors of patients with cancer. The investigators hypothesize that the detection of certain miRNAs present in the …

unresectable pancreatic cancer
measurable disease
metastasis
pancreaticoduodenectomy
adenocarcinoma
  • 0 views
  • 26 Jan, 2021
  • 1 location
Advanced Therapies for Liver Metastases (LiMeT)

Liver metastases (MTS) are the main cause of death for patients affected by colorectal carcinoma (CRC) and pancreatic ductal adenocarcinoma (PDAC), thus representing the major unmet clinical

Accepts healthy volunteers
  • 0 views
  • 24 Apr, 2022
  • 1 location
A New Scoring System for Perineural and Vascular Invasion in Pancreatic Cancer (VANISSh)

The aim of this study is to validate both retrospectively and prospectively a newly proposed scoring system for perineural and vascular invasion in pancreatic ductal cancer and correlate it with disease free survival, early recurrence, site of recurrence, overall survival and neoadjuvant treatment.

breast ductal carcinoma
pancreatectomy
pancreaticoduodenectomy
pancreatic resection
adenocarcinoma
  • 22 views
  • 12 Feb, 2022
  • 1 location
Pharmacotyping of Pancreatic Patient-derived Organoids

EUS-FNB samples will be used for organoid cultures, which will be co-cultured with cancer associated fibroblasts derived from the surrounding stroma of the lesion. The organoid cultures will be used for pharmacotyping using relevant chemotherapeutic agents used in the clinic, and the organoid's response compared with the patient's response.

pdac
antineoplastic
platelet count
  • 0 views
  • 22 Mar, 2022
Pilot Study of Pancreatic Cancer Screening

This study investigates how often abnormal findings from routine magnetic resonance imaging occur in people with genetic mutations in BReast CAncer gene. (BRCA), ataxia telangiectasia mutated gene (ATM), or PALB2 screened for pancreatic cancer. This study may lead to a greater understanding of cancer and potentially, improvements in cancer screening …

ATM
endoscopic ultrasound
Accepts healthy volunteers
palb2
  • 0 views
  • 29 Apr, 2022
  • 1 location
Retrospective Study on Microbial Diversity in Paraffin Tissue of Pancreatic Diseases

The great harm of pancreatic diseases and the unknown etiology and pathogenesis make it difficult to intervene in most early cases in time. Previous studies by scholars and applicants at home and abroad have shown that the microflora in pancreatic tissue is closely related to chronic pancreatitis and pancreatic cancer. …

pancreatitis
  • 0 views
  • 25 Mar, 2022
  • 1 location