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Found 199 clinical trials
Tusamitamab Ravtansine in Patients With CEACAM5-positive Advanced Solid Tumors (CARMEN-BT01)

Primary Objective: -To assess the antitumor activity of tusamitamab ravtansine in metastatic breast cancer (mBC) and metastatic pancreatic adenocarcinoma (mPAC) Secondary

  • 0 views
  • 17 Jun, 2022
  • 29 locations
Tusamitamab Ravtansine in Patients With CEACAM5-positive Advanced Solid Tumors (CARMEN-BT01)

Primary Objective: -To assess the antitumor activity of tusamitamab ravtansine in metastatic breast cancer (mBC) and metastatic pancreatic adenocarcinoma (mPAC) Secondary

  • 0 views
  • 28 Jun, 2022
  • 29 locations
A Study to Assess the Efficacy and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma

The purpose of this study is to confirm the recommended phase 2 dose (RP2D) of zolbetuximab in combination with Nab-P + GEM, determine overall survival and assess the safety and tolerability of the combination treatment. This study will also evaluate tumor markers and pharmacokinetics (PK) of zolbetuximab, Nab-P and GEM, …

cancer
cancer chemotherapy
metastatic pancreatic adenocarcinoma
adenocarcinoma
neutrophil count
  • 250 views
  • 03 Jun, 2022
  • 80 locations
High Volume Washing of the Abdomen in Increasing Survival After Surgery in Patients With Pancreatic Cancer That Can Be Removed by Surgery

This randomized clinical trial studies how well high volume washing of the abdomen works in increasing survival after surgery in patients with pancreatic cancer that can be removed by surgery. High volume washings may remove free floating cancers present after surgery and help prolong survival in patients with pancreatic cancer.

pancreaticoduodenectomy
cancer
  • 12 views
  • 23 Feb, 2022
  • 1 location
A Study of SGN-STNV in Advanced Solid Tumors

This trial will look at a drug called SGN-STNV to find out whether it is safe for patients with solid tumors. It will study SGN-STNV to find out what its side effects are. A side effect is anything the drug does besides treating cancer. It will also study how well …

breast cancer
cancer
cancer chemotherapy
carcinoma
adenocarcinoma
  • 0 views
  • 30 May, 2022
  • 15 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

03/20/2018) Rare pancreatic tumors including acinar cell carcinoma, mucinous cystadenocarcinoma or serous cystadenocarcinoma. Pancreatic adenocarcinoma is not eligible (closed to accrual

germ cell tumor of ovary
testicular
thyroidectomy
gastrointestinal stromal tumor
gallbladder cancer
  • 6632 views
  • 29 Jun, 2022
  • 759 locations
A Study of SGN-B6A in Advanced Solid Tumors

This trial will look at a drug called SGN-B6A to find out whether it is safe for people who have solid tumors. It will study SGN-B6A to find out what its side effects are. A side effect is anything the drug does besides treating cancer. It will also study whether …

breast cancer
cancer
carcinoma
adenocarcinoma
squamous cell carcinoma
  • 179 views
  • 19 Jun, 2022
  • 12 locations
Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

The main goal of this phase of the study is to determine if objectively assessed Physical Activity (PA) levels in advanced-cancer patients are associated with health care provider (HCP)-assessed ECOG performance status and overall survival. The purpose is to advance the evidence-base for incorporating objective assessment of Physical Activity (PA) …

radiation oncology
cyst
metastasis
non-melanoma skin cancer
neuroendocrine tumor
  • 43 views
  • 03 Jun, 2022
  • 1 location
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors (innovaTV 207)

This trial will study tisotumab vedotin to find out whether it is an effective treatment for certain solid tumors and what side effects (unwanted effects) may occur. There are four parts to this study. In Part A, the treatment will be given to participants every 3 weeks (3-week cycles). In …

carboplatin
gemcitabine
tyrosine
cancer
adenocarcinoma
  • 247 views
  • 30 Jun, 2022
  • 32 locations
First-in-human Study of DS-1062a for Advanced Solid Tumors (TROPION-PanTumor01)

This study is one single group of participants with non-small cell lung cancer (NSCLC) who have not been cured by other treatments. It is the first time the drug has been used in humans, and will be in two parts. The primary purpose of the parts are: Dose Escalation: To …

hormone therapy
epidermal growth factor
cancer
cancer chemotherapy
platinum-based chemotherapy
  • 280 views
  • 21 Mar, 2022
  • 14 locations