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Found 206 clinical trials
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Pancreatic Adenocarcinoma - Advanced

Pancreatic Adenocarcinoma - Advanced

  • 150 views
  • 08 Nov, 2020
  • 1 location
featured
RTOG 0848: A Phase III Trial Evaluating Both Erlotinib and Chemoradiation as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma.

RTOG 0848: A Phase III Trial Evaluating Both Erlotinib and Chemoradiation as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma.

  • 620 views
  • 08 Nov, 2020
  • 1 location
Trial of NanoPac in Subjects With Locally Advanced Pancreatic Adenocarcinoma

Open-label, dose-escalating, Phase IIa trial of NanoPac to treat subjects with locally advanced pancreatic adenocarcinoma via direct intratumoral injection.

  • 44 views
  • 25 Jan, 2021
  • 4 locations
Neo-adjuvant FOLF(IRIN)OX for Resectable Pancreatic Adenocarcinoma

In patients with resectable pancreatic duct adenocarcinoma (PDAC), curative surgery followed by adjuvant chemotherapy is currently the standard of care. However, the long-term results are still poor, with median disease-free and overall survival of 14 months and 23 months. The corresponding 5-year overall survival rate is 20%. Chemotherapy before surgery …

  • 7 views
  • 22 Jan, 2021
  • 1 location
Neoadjuvant GMCI Plus Chemoradiation for Advanced Non-Metastatic Pancreatic Adenocarcinoma

The purpose of this study is to evaluate Gene Mediated Cytotoxic Immunotherapy (GMCI) in combination with standard of care chemoradiation and surgery for borderline resectable and unresectable locally advanced pancreatic cancer in patients who have completed induction chemotherapy. GMCI kills tumor cells and creates an immune stimulatory environment in the …

neutrophil count
metastatic pancreatic adenocarcinoma
tumor cells
cancer
  • 0 views
  • 27 Jan, 2021
  • 5 locations
Gemcitabine & Nab-Paclitaxel in Pancreatic Adenocarcinoma With Positive Peritoneal Cytology

Using gemcitabine and nab-paclitaxel, the investigators hope to establish the differential ability of local and cytologically positive disease to respond to this regimen, and in particular, the frequency of cytologic conversion from positive to negative in such patients. The investigators also can begin to assess the value of maximum local …

platelet count
measurable disease
gemcitabine
pancreatic ductal adenocarcinoma
cancer
  • 2 views
  • 30 Jul, 2021
  • 1 location
APG-1387 Plus Chemotherapy in Advanced Pancreatic Adenocarcinoma

This study is a two stage study consisting of a dose escalation phase Ib and a phase II study which include subjects with previously-treated, advanced pancreatic adenocarcinoma. Dose Limiting

  • 0 views
  • 09 Aug, 2021
  • 1 location
Niraparib + Ipilimumab or Nivolumab in Progression Free Pancreatic Adenocarcinoma After Platinum-Based Chemotherapy

The main purpose of this study is to look at the effectiveness, safety, and anti-tumor activity (preventing growth of the tumor) of the drugs Niraparib with either Ipilimumab or Nivolumab on patients and their pancreatic cancer.

ipilimumab
oxaliplatin
nivolumab
cancer
metastasis
  • 23 views
  • 22 Jun, 2021
  • 1 location
Effect of Intratumoral Injection of Gene Therapy for Locally Advanced Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is the fifth leading cause of cancer-related death in Western countries, and its incidence has increased over the last 40 years. Curative surgery to manage PDAC is possible in only a fraction of patients; indeed, a vast majority (85%) of patients is diagnosed with locally advanced …

folfirinox
gemcitabine
pancreatic ductal adenocarcinoma
cancer
ductal adenocarcinoma
  • 27 views
  • 24 Jan, 2021
  • 10 locations
A Study of Nal-IRI With 5-FU Levofolinic Acid and Oxaliplatin in Patients With Resectable Pancreatic Cancer

Rational:Pancreatic cancer is a systemic disease at the time of diagnosis, even among patients with apparent localized disease. Surgical resection is the only potentially curative therapy for pancreatic cancer, but in patients who undergo surgery and postoperative therapy, metastatic relapse remains common and no more than 20% of patients achieve …

oxaliplatin
folfirinox
celiac
measurable disease
fluorouracil
  • 3 views
  • 08 Aug, 2021
  • 1 location