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Found 43 clinical trials
High Volume Washing of the Abdomen in Increasing Survival After Surgery in Patients With Pancreatic Cancer That Can Be Removed by Surgery

This randomized clinical trial studies how well high volume washing of the abdomen works in increasing survival after surgery in patients with pancreatic cancer that can be removed by surgery. High volume washings may remove free floating cancers present after surgery and help prolong survival in patients with pancreatic cancer.

pancreaticoduodenectomy
cancer
  • 12 views
  • 23 Feb, 2022
  • 1 location
Transfusion Trigger After Operations in High Cardiac Risk Patients (TOP)

The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb < 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is associated with decreased risk of adverse postoperative outcomes compared to a restrictive transfusion …

ischemia
percutaneous coronary intervention
vascular surgical procedures
Accepts healthy volunteers
exercise stress test
  • 12 views
  • 12 Apr, 2022
  • 14 locations
Preoperative Endoscopic Pancreatic Stent for Distal Pancreatectomy

Distal pancreatectomy (DP) with or without splenectomy is commonly indicated for pancreatic body or tail lesions. Postoperative pancreatic fistula (POPF) remains the commonest complication after

  • 0 views
  • 09 Apr, 2022
  • 1 location
Total pancrEaTectomy vs High-Risk Pancreatic anastomosiS (TETRIS)

Postoperative pancreatic fistula (POPF) is the main driver of surgical morbidity after pancreatoduodenectomy (PD). The aim of the present study is to compare total pancretectomy (TP) and primary pancreatic anastomosis (PA) in a cohort of extremely high-risk patients, with regards to postoperative outcomes and quality of life (QoL).

  • 0 views
  • 23 Mar, 2022
Routine Staple Line Reinforcement for Minimally Invasive Distal Pancreatectomy

Postoperative fistula is the major complications of distal pancreatectomies which prohibit patients' recovery. Previous studies have reported controversial results regarding the efficacy of pancreatic stump reinforcement methods. Prior research has commonly included minimally invasive and open cases together. Moreover, stapler and suture were combined in most studies making interpretation difficult. …

  • 0 views
  • 18 Feb, 2021
  • 1 location
Early Drain Removal Versus Standard Drain Management After Distal Pancreatectomy (Early-Dist)

Main indications for distal pancreatectomy (DP) are pancreatic body and tail tumors including ductal adenocarcinoma, neuroendocrine tumors, and cystic neoplasms. Despite a less invasive

  • 0 views
  • 03 Feb, 2021
  • 1 location
Intra-Portal Alone Versus Intra- and Extra-Portal Transplantation of Pancreatic Islets After Total Pancreatectomy for Chronic Pancreatitis (iSite)

Randomized pilot trial of patients (n=30) undergoing Total Pancreatectomy and Islet AutoTransplant (TPIAT). Patients with islet harvest of greater than 5000 islet equivalents/kg body weight will

pancreatectomy
Accepts healthy volunteers
  • 0 views
  • 15 Feb, 2022
  • 1 location
Isolation Procedure vs. Conventional Procedure During Distal Pancreatectosplenectomy for Pancreatic Cancer

In the distal pancreatectomy (including pancreatic tail resection) for invasive ductal carcinoma of the pancreas, we evaluate the usefulness of a procedure of firstly transection of splenic

  • 0 views
  • 26 Jan, 2021
  • 10 locations
Lidocaine Infusion in Pancreatic Cancer

This study elucidates the effects of the intravenous (IV) lidocaine infusion on the biology of pancreatic circulating tumor cells (CTCs) isolated from patients undergoing robotic pancreatectomy

pancreatectomy
pancreatic adenocarcinoma
endocrine therapy
tumor cells
measurable disease
  • 11 views
  • 25 Apr, 2022
  • 1 location
Autologous Mesenchymal Stromal Cells and Islet Co-transplantation in TP-IAT

This is a clinical trial for non-diabetic chronic pancreatitis (CP) patients undergoing total pancreatectomy with islet autotransplantation (TP-IAT). Participants will be randomized to either

  • 0 views
  • 14 Apr, 2022
  • 1 location