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Found 41 clinical trials
Distal Pancreatectomy Minimally Invasive or Open for Malignancy (DIPLOMA)

approach (MIDP vs ODP). A blinded adjudication committee will assess all endpoints. Study population: Two groups of 129 patients (258 in total) with an indication for elective distal pancreatectomy

cancer
pdac
  • 0 views
  • 28 Oct, 2021
  • 5 locations
Laparoscopic Versus Open Distal Pancreatectomy for Pancreatic Cancer: a Multicenter Randomized Controlled Trial

When pancreatic cancer of the body and tail is diagnosed, a distal pancreatectomy is planned. This operation can be performed with open surgery, or with laparoscopic surgery. This study is a

Accepts healthy volunteers
  • 2 views
  • 10 Feb, 2022
  • 1 location
Minimally Invasive Versus Open Radical Pancreatectomy After Neoadjuvant Chemotherapy for Pancreatic Cancer

The aim of this study is to evaluate the safety and effectiveness of minimally invasive versus open radical pancreatectomy after neoadjuvant chemotherapy for pancreatic ductal adenocarcinoma

  • 0 views
  • 18 Sep, 2021
  • 178 views
  • 27 Feb, 2022
  • 1 location
Pancreatic Adenocarcinoma Neoadjuvant Combination Chemotherapy and Stereotactic Body Radiation Therapy Before Surgery

) and chemotherapy with mFOLFIRINOX or gemcitabine / nab-paclitaxel followed by pancreatectomy.

  • 0 views
  • 18 Sep, 2021
  • 1 location
RADIOFREQUENCY-ASSISTED TRANSECTION OF THE PANCREAS VS STAPLER

quality of lymphatic resection). Methodology: Phase III prospective multicenter study in patients undergoing distal pancreatectomy for any origin. All consecutive patients who undergo a distal

  • 0 views
  • 02 Sep, 2021
  • 1 location
A Study of Nal-IRI With 5-FU, Levofolinic Acid and Oxaliplatin in Patients With Resectable Pancreatic Cancer (nITRo)

Rational:Pancreatic cancer is a systemic disease at the time of diagnosis, even among patients with apparent localized disease. Surgical resection is the only potentially curative therapy for pancreatic cancer, but in patients who undergo surgery and postoperative therapy, metastatic relapse remains common and no more than 20% of patients achieve …

measurable disease
resectable pancreatic cancer
irinotecan
oxaliplatin
folfirinox
  • 3 views
  • 03 Mar, 2022
  • 1 location
The Combination Chemotherapy of SIRIOX as First- or Second-Line Chemotherapy for Pancreatic Cancer

Pancreatic cancer represents the most lethal of the common malignancies with a 5-year survival rate of less than 5%. For patients who are eligible for potentially curative resection, despite mortality and morbidity rates after surgery have improved, the recurrence rate is up to 85% within 2 years. FOLFIRINOX (fluoropyrimidine/leucovorin plus …

  • 16 views
  • 26 Feb, 2022
  • 2 locations
High Volume Washing of the Abdomen in Increasing Survival After Surgery in Patients With Pancreatic Cancer That Can Be Removed by Surgery

This randomized clinical trial studies how well high volume washing of the abdomen works in increasing survival after surgery in patients with pancreatic cancer that can be removed by surgery. High volume washings may remove free floating cancers present after surgery and help prolong survival in patients with pancreatic cancer.

cancer
pancreaticoduodenectomy
  • 12 views
  • 23 Feb, 2022
  • 1 location
Transfusion Trigger After Operations in High Cardiac Risk Patients (TOP)

The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb < 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is associated with decreased risk of adverse postoperative outcomes compared to a restrictive transfusion …

exercise stress test
vascular surgical procedures
Accepts healthy volunteers
percutaneous coronary intervention
stroke
  • 12 views
  • 12 Apr, 2022
  • 14 locations