Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 10 clinical trials
Cisplatin Disposition and Kidney Injury

This study is being done to determine 1) whether drugs to treat cisplatin-related nausea can influence harm to the kidneys, 2) whether cisplatin levels in the body can influence the risk of harm to the kidneys, and 3) whether a person's genetic make-up can increase or decrease the likelihood of …

  • 0 views
  • 08 Oct, 2021
  • 2 locations
Netupitant/Palonosetron Hydrochloride and Dexamethasone With or Without Prochlorperazine or Olanzapine in Improving Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer

This randomized phase III trial studies how well netupitant/palonosetron hydrochloride and dexamethasone with prochlorperazine or olanzapine work compared to netupitant/palonosetron

cyclophosphamide
breast cancer
herceptin
trastuzumab
carboplatin
  • 29 views
  • 24 May, 2022
  • 15 locations
Triple Therapy for Postoperative Nausea and Vomiting in Laparoscopic Gastrointestinal Surgery

Postoperative nausea and vomiting (PONV) are common in patients, especially in patients at high risk. PONV may result in prolonged hospital stay and threaten patients' life. Because the etiology of PONV is very complex, there is an increasing focus on combining antiemetics from different classes for PONV prophylaxis. Fosaprepitant is …

  • 0 views
  • 21 Nov, 2021
  • 1 location
Oral Akynzeo vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk)

MyRisk: Efficacy and safety evaluation of oral Akynzeo in patients receiving MEC at high risk of developing CINV based on a prediction tool. A multinational and multicenter study. Antiemetic guidelines recommendations are based on the emetogenic potential of the chemotherapy. Chemotherapy (CT) agents are divided in Highly, Moderately, Low and …

  • 3 views
  • 25 Sep, 2021
  • 5 locations
Palonosetron and Blood Coagulation

Palonosetron may alter whole blood coagulation. However, little is known about the dose-response relationships according to the blood concentration of palonosetron. The investigators therefore

Accepts healthy volunteers
thromboelastometry
palonosetron
  • 0 views
  • 23 Apr, 2022
  • 1 location
Buccal Film vs IV Palonosetron for Prevention of CINV in Cancer Patients Receiving MEC

The phase 3 study is to compare the efficacy and safety of palonosetron, a long-acting 5-HT3 receptor antagonist, by buccal film delivery compared to IV injection for the prevention of

  • 0 views
  • 14 Apr, 2022
  • 1 location
Safety and Antiemetic Efficacy of Akynzeo Plus Dexamethasone During Radiotherapy and Concomitant Weekly Cisplatin

This is a multicentre, single-arm, phase II study to investigate the safety and antiemetic efficacy of Akynzeo (a fixed dose combination of palonosetron and netupitant) plus dexamethasone in

netupitant
emetic
akynzeo
absolute neutrophil count
dexamethasone
  • 7 views
  • 15 Feb, 2022
  • 1 location
The Optimization of Antiemetic Regimen for C-RINV in LA-HNSCCs

This study sought to investigate the efficacy and safety of a three-drug combination antiemetic regimen of olanzapine combined with aprepitant and palonosetron for the prevention of

olanzapine
carcinoma
cavity
aprepitant
nausea
  • 0 views
  • 21 Mar, 2022
AKY15-HK-301_NEPA Study

response to conditions that affect the gut and the vomiting center, which is an area in the brain. Netupitant and palonosetron are drugs that are thought to block the activation of certain types of

cyclophosphamide
adjuvant chemotherapy
adriamycin
cancer treatment
mammogram
  • 0 views
  • 27 Feb, 2022
  • 1 location
Bendamustine Plus Subcutaneous Rituximab in Patients With Diffuse Large B-cell Lymphoma

This is an open-label, multi-center, prospective, single arm phase 2 trial of the combination of bendamustine and rituximab in patients with PTLD, monomorphic cluster of differentiation antigen 20(CD20) positive DLBCL. The investigators want to investigate the efficacy and safety of the combination of bendamustine and rituximab in patients with previously …

rituximab
bendamustine
renal function
b-cell lymphoma
platelet count
  • 11 views
  • 21 Jan, 2021
  • 1 location