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Found 9 clinical trials
Study of Palliative Radiation Therapy vs. no Palliative Radiation Therapy for Patients With High Risk Bone Metastases That Are Not Causing Significant Pain

The purpose of the study is to compare the outcome of patients who receive standard treatment versus those who receive preventative radiation and then standard treatment.

  • 51 views
  • 11 Dec, 2020
  • 10 locations
Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer

This phase II trial studies how well single-fraction stereotactic body radiation therapy (SBRT) works when compared to standard radiation therapy in treating patients with cancer that has spread to other places in the body (metastatic). Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to …

tumor cells
metastasis
cancer
  • 0 views
  • 24 Jan, 2021
  • 2 locations
Study of Durvalumab Following Radiation Therapy in Patients With Stage 3 Unresectable NSCLC Ineligible for Chemotherapy

hypofractionated bioequivalent dose (BED)]; Cohort B: palliative radiation therapy [40 to < 54 Gy or hypofractionated BED]).

  • 0 views
  • 19 Jan, 2021
  • 29 locations
Access to Single-Fraction Palliative Radiation Therapy in Cancer Patients Enrolled in Hospice

Feasibility study to report on the impact of ACCESS of single-fraction radiation therapy on cancer patients with bone metastases enrolled in hospice care.

cancer
solid tumor
metastasis
bone metastases
  • 0 views
  • 23 Jan, 2021
  • 1 location
Palliative RT & Anti-PD-1/PD-L1 Checkpoint Blockade in Metastatic Merkel Cell Carcinoma

The primary objectives of this study are to assess 1) the safety and 2) efficacy of combining Anti-PD-1/PD-L1 blockade with palliative radiation therapy in patients with Stage IV Merkel Cell

immunomodulator
metastasis
hysterectomy
positron emission tomography
follicle stimulating hormone
  • 2 views
  • 24 Jan, 2021
  • 1 location
Durvalumab Tremelimumab and Hypofractionated Radiation Therapy in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

This phase I/II trial studies the side effects of durvalumab, tremelimumab and hypofractionated radiation therapy in treating patients with head and neck squamous cell carcinoma that has come back (recurrent) or that has spread to other places in the body (metastatic). Immunotherapy with monoclonal antibodies, such as durvalumab and tremelimumab, …

  • 4 views
  • 24 Dec, 2020
  • 1 location
Pulsed Low Dose Rate Radiation Therapy for Gastric Cancer Patients With Peritoneal Metastasis

This phase II trial studies the side effects and response of pulsed low dose rate radiation therapy in treating gastric cancer patients with peritoneal metastasis.

cancer chemotherapy
metastasis
solid tumor
gastric adenocarcinoma
cancer
  • 11 views
  • 21 Jan, 2021
  • 1 location
Phase I Trial of Adjuvant Pembrolizumab After Radiation Therapy for Lung-Intact Malignant Pleural Mesothelioma

This phase I trial studies the side effects and best way to give pembrolizumab after radiation therapy in treating patients with pleural malignant mesothelioma. Radiation therapy uses high energy radiation to kill tumor cells and shrink tumors. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system …

pemetrexed
metastasis
pneumonectomy
erythropoietin
cancer
  • 64 views
  • 23 Jan, 2021
  • 2 locations
IT-hu14.18-IL2 With Radiation Nivolumab and Ipilimumab for Melanoma

This phase I/II trial is designed to determine the maximum tolerated dose or the maximum administered dose of intratumoral administration of hu14.18-IL2 and to evaluate side effects of intratumoral hu14.18-IL2 when given alone, after radiation therapy, after radiation therapy and in combination with nivolumab, and after radiation therapy and in …

tumor cells
gilbert's syndrome
metastasis
nivolumab
cancer
  • 5 views
  • 04 Dec, 2020
  • 1 location