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Found 91 clinical trials
Treatment of Metastatic Breast Cancer With Fulvestrant Plus Palbociclib or Tamoxifen Plus Palbociclib

To assess longitudinal changes in allele frequency of ESR1 mutation in plasma in patients treated with Fulvestrant plus palbociclib compared to tamoxifen plus palbociclib

metastasis
tamoxifen
measurable disease
immunological adjuvant
hormone therapy
  • 1 views
  • 26 Jan, 2021
  • 1 location
Palbociclib After CDK and Endocrine Therapy (PACE)

Palbociclib Fulvestrant with Palbociclib and Avelumab

metastasis
tamoxifen
immunological adjuvant
abemaciclib
fulvestrant
  • 27 views
  • 01 Feb, 2021
  • 23 locations
Palbociclib and Cetuximab in Metastatic Colorectal Cancer

This research study is designed to provide a better understanding of study drugs cetuximab (Erbitux) and palbociclib when used in combination to treat patients with metastatic colon cancer.

metastasis
KRAS
fluoropyrimidine
fluorouracil
neutrophil count
  • 343 views
  • 25 Jan, 2021
  • 1 location
Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

The proposed study is a single-arm, multi-center, open-label phase II study of the combination of palbociclib and ibrutinib in patients with previously treated mantle cell lymphoma to evaluate

measurable disease
ibrutinib
prednisone
mantle cell lymphoma
immunosuppressive agents
  • 23 views
  • 25 Jan, 2021
  • 8 locations
T-DM1 and Palbociclib for Metastatic HER2 Breast Cancer

This is a randomized phase II study to evaluate if the combination of T-DM1 with palbociclib improves progression-free survival compared to single agent T-DM1in patients with metastatic HER2

metastasis
pertuzumab
breast cancer
HER2
palbociclib
  • 45 views
  • 26 Jan, 2021
  • 16 locations
The Resistance and Immune Response to Palbociclib in Breast Cancer

Breast Cancer (BC) treated with Palbociclib in combination with endocrine therapies.

endocrine therapy
hormone therapy
palbociclib
breast cancer
  • 4 views
  • 22 Jan, 2021
  • 1 location
Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors

This phase I trial studies the side effects and best dose of palbociclib with cisplatin or carboplatin in treating patients with solid tumors that have spread to other places and usually cannot

metastasis
squamous non-small cell lung cancer
palbociclib
neutrophil count
solid tumors
  • 216 views
  • 19 Feb, 2021
  • 1 location
Palbociclib in Patients With Metastatic Castration-Resistant Prostate Cancer

The purpose of this study is to find out what effects a new drug, palbociclib, has on prostate cancer and will look at the side effects of treatment with palbociclib. The researchers doing this

metastasis
antiandrogens
diphosphonates
arn-509
luteinizing hormone-releasing hormone agonist
  • 408 views
  • 24 Feb, 2021
  • 12 locations
Rogaratinib Palbociclib y Fulvestrant in Patients With Breast Cancer.

inhibitor plus palbociclib, abemaciclib or ribociclib, according RECIST 1.1 criteria.

  • 0 views
  • 27 Jan, 2021
  • 8 locations
Palbociclib and INCMGA00012 in People With Advanced Liposarcoma

The researchers are doing this study to find out whether combining the study drugs palbociclib and INCMGA00012 is an effective and safe treatment for advanced liposarcoma.

metastasis
measurable disease
liposarcoma
neutrophil count
systemic therapy
  • 0 views
  • 29 Jan, 2021
  • 1 location