Found 107 clinical trials
Breath Metabolomics of Placebo Effects a Pilot Study
This study is to analyze the breath metabolome before and after the administration of a placebo in an established experimental pain procedure in healthy subjects in order to investigate placebo effects, and whether they induce any measurable changes at the metabolic level.
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- 03 Nov, 2021
- 1 location
Could Peri-anal Block be Effective as Caudal Block in Trans-anal Pull-through Surgery ??.
IN pediatric patient population pain is considered one of the most misunderstood; under diagnosed and under treated medical problems. If left uncontrolled, pain may have a diverse effect on all aspects of life as it is only a sensory perception but also has emotional, cognitive and behavioral components.
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- 30 Aug, 2021
- 1 location
TENS for Testicular Pain (ICO): A Randomized Controlled Trial
Idiopathic Chronic Orchialgia (i.e., testicular pain) is a challenging condition to treat, with unresolved testicular pain leading to distress, diminished activities of daily living and decreased quality of life. Testicular Pain may be caused by a tumor, hernia, infection, trauma, vein compression, cysts, and/or postoperative or radiating pain, though is …
- 15 views
- 07 May, 2021
- 1 location
Effect of a Bolus of Clonidine Systemically Administered on the Excitability of the Spinal Motoneurons of the Lower Extremity
The purpose of this study is to assess the effect of IV clonidine administration on lower limb spinal motoneuron excitability during standardized total intravenous anesthesia (propofol and remifentanil).
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- 24 Jan, 2021
- 1 location
LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs
This will be a single-center, prospective, randomized controlled cross-sectional study comparing interscalene brachial plexus block with liposomal bupivacaine versus bupivacaine with epinephrine and PF dexamethasone in patients undergoing primary shoulder arthroplasty. Primary endpoint will be total opioid consumption in the first three post-operative days.
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- 03 Sep, 2021
- 1 location
Narcotic Versus Non-narcotic Medication for Pain Management After Wrist/Hand Fractures
The purpose of this study is to evaluate two drug options for pain control in patients following wrist injury. Participants will be randomized to one of the 2 pain relief treatments to determine what treatment provides the most effective pain relief
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- 11 Mar, 2021
- 1 location
Paracervical Injection for Headache in the Emergency Department
Headache is one of the most common presenting complaints in the emergency department.1 By the time patients with benign headaches present for treatment in the ED, they often have exhausted non-invasive treatments, and physicians are left with few therapeutic options. The investigators therefore propose to study the use of paracervical …
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- 10 Dec, 2021
- 1 location
Liposomal Bupivacaine vs Bupivacaine for Pain Control After Sternotomy
Researchers hope to learn whether giving the longer-acting local anesthetic liposomal bupivacaine prior to closing the sternum is more effective in managing pain following sternotomy, than in patients who received standard bupivacaine before sternal closure. Researchers will measure this based on how much IV pain medication is used, rates on …
- 0 views
- 25 Jan, 2021
- 1 location
Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery
Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery. Surgery is potentially associated with a number of postoperative complications, whether cardiovascular, respiratory, infectious, thromboembolic, or digestive Although they do not inevitably lead to a life-threatening prognosis, in many cases these complications …
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- 28 Mar, 2021
- 1 location
Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques
To estimate the dose of bupivacaine required to achieve initial effective comfort in 90% of patients (ED90) via the epidural (DPE or EPL) technique in women undergoing labor.
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- 31 Mar, 2021
- 1 location