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Found 246 clinical trials
Featured trial
Diabetic Painful Neuropathy Study: A New Pain Relief Medication

We are currently seeking volunteers with either Type 1 or Type 2 diabetes, and who experience painful diabetic neuropathy daily. This is a study of a new investigational oral medication that may help to relieve the pain of diabetic neuropathy. Eligible participants will be determined based on results from lab …

hemoglobin a1c
painful diabetic neuropathy
  • 12 Oct, 2021
  • 1 location
Featured trial
A Randomized Controlled Trial of Regional versus General Anesthesia for Promoting Independence after Hip Fracture (REGAIN Trial)

A Randomized Controlled Trial of Regional versus General Anesthesia for Promoting Independence after Hip Fracture (REGAIN Trial)

  • 23 Nov, 2020
  • 1 location
A Randomized, Double-Blind, Single-Dose, Parallel, Placebo-Controlled Pivotal Trial to Confirm the Efficacy of a Fixed Dose Combination Tablet of Naproxen Sodium and Caffeine to Effectively Alleviate Postsurgical Dental Pain

chance) assigned to one of the five treatment groups. They will take a single dose of two tablets by mouth within 4.5 hours after the surgery. If there is no pain relief within 2 hours after intake

Accepts healthy volunteers
  • 24 Oct, 2022
  • 1 location
The Effect of the Use of Peanut Ball on Labor Time in Nulliparous Women

Peanut ball use has become popular with midwives and nurses because it is an inexpensive, nonpharmacological intervention that can help with positioning the patient to decrease labor time. The peanut ball allows the patient to reposition her legs in a way that mimics squatting and changes the diameter of the …

Accepts healthy volunteers
  • 04 Oct, 2022
  • 2 locations
A Study of Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries: The No OUCH Trials (No OUCH)

Musculoskeletal (MSK) injuries, including limb injuries, are the most common cause for Emergency Department (ED) visits for children with pain. Broken arms and legs are known to cause moderate to severe pain in most children, yet previous research shows that children's pain in the emergency department is still under-treated. Further, …

  • 28 Oct, 2022
  • 13 locations
Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled Study of BOTOX (Botulinum Toxin Type A) for the Prevention of Migraine in Subjects With Episodic Migraine

Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound (ICHD 2018). Migraine can be further categorized according to the frequency of attacks as episodic migraine (EM) or chronic migraine (CM). This study will assess the effects of BOTOX …

  • 27 Oct, 2022
  • 115 locations
The Role of Transcutaneous Electrical Nerve Stimulation (TENS) for Menstrual Pain Relief: A Randomized Control Trial

The present study aims to verify the analgesic potential of a transcutaneous electrical nerve stimulation (TENS) device using patients with primary dysmenorrhea and compare it with a control period without usage.

Accepts healthy volunteers
  • 15 Oct, 2022
  • 1 location
Dural Puncture Epidural Versus Epidural Anesthesia for Cesarean Delivery

of this study will help anesthesiologists know which anesthetic technique can provide faster and potentially better at providing pain relief for cesarean sections.

  • 07 Oct, 2022
  • 1 location
Evaluation of Sonalleve MR-HIFU for Non-invasive Thermal Therapy of Facet-Joint Syndrome: Feasibility and Safety Clinical Study (HIFU-FACET)

Patients suffering from facet-joint-syndrome associated with lower-back pain will be treated with MRI-guided High Intensity Focused Ultrasound thermal therapy for pain relief.

  • 14 Oct, 2022
NPC-06 to Pain Associated With Acute Herpes Zoster

To confirm the pain relief effect and the safety of NPC-06 (fosphenytoin sodium hydrate) in patients with pain associated with acute herpes zoster in a placebo-controlled, double-blind, parallel

  • 07 Oct, 2022
  • 10 locations