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Found 14 clinical trials
Role of Blood Management in Perioperative Outcomes

There is currently limited information regarding the role of blood management in the benign gynecologic population and specifically, in patients who are scheduled to undergo surgery for fibroids and/or abnormal uterine bleeding. A thorough search through PubMed and clinicaltrials.gov did not reveal any studies on this issue. In 2019 at …

  • 0 views
  • 03 Feb, 2021
  • 1 location
The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial

This is a Phase III multicentre randomized controlled trial (RCT) to evaluate the impact of tranexamic acid (TXA) on perioperative blood transfusion in patients undergoing liver resection. The rationale for this study includes: (1) experimental evidence supporting the use of TXA in other surgical populations; (2) lack of evidence in …

blood transfusion
primary cancer
liver surgery
cancer
  • 15 views
  • 26 Jan, 2021
  • 11 locations
Treatment of Anemia With Intravenous Iron in Patients Listed for Orthotopic Liver Transplantation

) increases hemoglobin concentrations and reduces intraoperative transfusion of packed red blood cells (PRBCs). The investigators hypothesize that therapy with intravenous iron will increase hemoglobin

blood transfusion
packed red blood cells
orthotopic liver transplant
  • 0 views
  • 25 Jan, 2021
  • 1 location
Evaluation and Treatment of Iron Deficiency in Ovarian Cancer Patients

transfusion of packed red blood cells in the peri-operative period. 21 participants at least 18 years of age with epithelial ovarian cancer of any stage requiring neoadjuvant chemotherapy and surgery will be

blood transfusion
cancer
debulking surgery
iron sucrose
iron
  • 0 views
  • 27 Jan, 2021
  • 1 location
TRANexamic Acid to Reduce Bleeding in BURN Surgery

). Transfused patients had a total median blood loss of 2468 mL and an average number of 4 packed red blood cells (PRBC) administered. Among the various methods that help limit blood loss, tranexamic

tranexamic acid
packed red blood cells
  • 34 views
  • 27 Jan, 2021
  • 7 locations
Aortic Valve Sparing Root Replacement Versus Bentall

> primary outcome measures: Intraoperative or intrahospital death. Reexploration for bleeding. Units of packed red blood cells.

  • 0 views
  • 25 Jan, 2021
  • 1 location
Transfusion of Biotinylated Red Blood Cells

The purpose of this research is to study how red blood cells (RBCs) survive in a person's circulation, and how that survival may be different in red blood cells that are donated and stored prior to being transfused. Investigators will study this by collecting blood samples from participants, "labeling" RBCs …

blood transfusion
vitamins
  • 33 views
  • 27 Jan, 2021
  • 1 location
Transfusion of Red Blood Cells Tranexamic Acid and Fibrinogen Concentrate for Severe Trauma Hemorrhage at Pre-hospital Phase of Care.

This is a single-center, not-randomized, open-label, controlled pilot clinical trial. This study compares presence of Trauma Induced Coagulopathy (TIC) and acute traumatic hemorrhage treatment at pre-hospital phase of care with red blood cells (RBC), Tranexamic acid (TXA) and Fibrinogen Concentrate (FC) with the current treatment based on the administration of …

blood transfusion
tranexamic acid
coagulopathy
traumatic hemorrhage
fibrinogen
  • 2 views
  • 15 Apr, 2021
  • 1 location
Mild vs Moderate Hypothermic Circulatory Arrest With Unilateral Anterograde Cerebral Perfusion in Hemiarch Replacement

The aim of our study is to analyze the immediate and long-term results between patients undergoing hemiarch replacement with ACP under mild hypothermic (30-32 C) circulatory arrest versus moderate hypothermic (26-28 C) circulatory arrest. It is hypothesized that circulatory arrest using mild hypothermia (30-32C) and uSACP will result in complications …

  • 0 views
  • 15 Apr, 2021
  • 1 location
Trial of Therapeutic Hypothermia in Patients With ARDS

Acute Respiratory Distress Syndrome (ARDS) is a serious condition that occurs as a complication of medical and surgical diseases, has a mortality of ~40%, and has no known treatment other than optimization of support. Data from basic research, animal models, and retrospective studies, case series, and small prospective studies suggest …

acute respiratory distress
neuromuscular blocking agents
bilateral pulmonary infiltrates
positive end expiratory pressure
FIO2
  • 0 views
  • 16 Jul, 2021
  • 14 locations