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Found 11 clinical trials
  • 0 views
  • 25 Oct, 2022
Oral Administration or Nasal Feeding of Huzhangxiefei Decoction for Treatment in Sepsis Induced Acute Lung Injury

> Hypothesis 1B: Oral Administration or Nasal Feeding of Huzhangxiefei Decoction will attenuate sepsis-induced lung injury as assessed by the respiratory rate and oxygenation index. Hypothesis 1C: Oral

FIO2
vasoconstrictors
resuscitation
urine output
coagulopathy
  • 0 views
  • 02 Dec, 2021
  • 1 location
Early Use of Prone Position in ECMO for Severe ARDS

a few cohort studies have reported that VV-ECMO combined with prone position could improve the oxygenation index and respiratory system compliance during the late period of treatment. This study

mechanical ventilation
FIO2
pneumonia
acute respiratory distress
ventilator-induced lung injury
  • 2 views
  • 25 Feb, 2022
  • 1 location
Lung Ultrasound-guided Fluid Therapy in Pediatric Intensive Care Unit Patients

A randomized clinical trial to evaluate the effect of using pulmonary ultrasound to guide fluid therapy on distinct variables.

fluid therapy
  • 0 views
  • 04 Oct, 2022
  • 1 location
Infants With Severe Acute Respiratory Distress Syndrome: The Prone Trial

The main objective is to determine the short-term effect of prone positioning in infants with infection-associated severe acute respiratory distress syndrome. The investigators compare oxygenation parameters and measurements from electrical impedance tomography (EIT) and lung ultrasonography (LUS) in mechanically ventilated infants in prone position versus supine position after surfactant administration.

  • 0 views
  • 04 Oct, 2022
  • 1 location
Clinical Efficacy of Megadose Vitamin C in Sepsis (CEMVIS)

In this multicenter, randomized, single-blind, placebo-controlled clinical trial. Patients will be randomly assigned to receive Vitamin C or placebo for 4 days or until ICU discharge (whatever come first). The primary outcome is 28-day all-cause mortality.

procalcitonin
  • 0 views
  • 06 Mar, 2022
  • 1 location
Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock (CORVICTES-ΥΜ)

This study has been approved as a nested substudy of a multicenter trial (CORVICTES, Clinicaltrials.gov Identifier: NCT03592693). The current, randomized, placebo-controlled study will compare steroids/vitamin C versus placebo/placebo in septic shock, with respect to cerebral autoregulation, biomarkers, and functional outcome. The following hypotheses will be tested: The steroids/vitamin C/thiamine intervention …

thiamine
  • 10 views
  • 22 Mar, 2022
  • 1 location
Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration (REALIST) (REALIST)

Acute Respiratory Distress Syndrome (ARDS) causes the lungs to fail due to the collection of fluid in the lungs (pulmonary oedema). ARDS is common in severely ill patients in Intensive Care Units and is associated with a high mortality and a high morbidity in those who survive. ARDS occurs in …

mechanical ventilation
FIO2
acute respiratory distress
chest x-ray
fluid overload
  • 51 views
  • 08 Jun, 2022
  • 1 location
Early Predictors of Necrotizing Enterocolitis in Neonates

The goal of this project is to identify neonates who are predisposed to Necrotizing Enterocolitis (NEC). the investigators will determine the effectiveness of non-invasive measures as well as biochemical markers to identify neonates early in the disease process. Thus, the investigators aim to identify infants with NEC prior to the …

  • 0 views
  • 10 Aug, 2021
  • 2 locations
Transcutaneous Carbon Dioxide Monitoring in Neonates Receiving Therapeutic Hypothermia for Neonatal Encephalopathy

The aim of our study is to evaluate the feasibility of applying transcutaneous CO2 monitoring (tcPCO2) in neonates receiving therapeutic hypothermia and to quantify the agreement between tcPCO2 and PCO2 in this population with or without respiratory support. Although, transcutaneous measurement of CO2 tension is the most commonly used non-invasive …

  • 0 views
  • 21 Apr, 2022