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Found 304 clinical trials
Featured trial
Clinical Validation of At-Home Methods of Sleep Assessment in Rett Syndrome

protocol with monitoring of respiratory effort, nasal airflow, blood oxygen saturation, heart rate, electrooculography (EOG), surface electromyography (EMG), and EEG.  

  • 15 Feb, 2022
  • 1 location
A Multicenter Study of the Efficacy and Safety of Esketamine for Analgesia During Cesarean Section

This study proposed applying intravenous Esketamine to cesarean section in parturient, detecting the plasma concentration of Esketamine in maternal blood, neonatal umbilical venous blood and umbilical arterial blood when the baby is delivered ketamine blood drug concentration, observing vital signs, adverse visual analog pain score (VAS), and sedation score (Ramsay) …

  • 25 Mar, 2022
  • 1 location
Safety and Efficacy of T89 in the Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)

The specific aim of this double blind, randomized phase III trial is to evaluate the safety and efficacy of T89 in preventing Acute Mountain Sickness (AMS) and relieving the symptoms of AMS after rapid ascent.

  • 16 Aug, 2021
  • 1 location
Feasibility and Acceptability Followed by Effectiveness of bCPAP for Treatment of Children Aged 1-59 Months With Severe Pneumonia in Ethiopia

Principal Investigator: Mohammod Jobayer Chisti Research Protocol Title: Feasibility and Acceptability Followed by Effectiveness of Bubble Continuous Positive Airway Pressure (bCPAP) for Treatment of Children aged 1-59 months with Severe Pneumonia in Ethiopia: A Cluster Randomized Controlled Clinical Trial Proposed start date: 1st July 2018, Estimated end date: 31st December …

  • 06 Nov, 2021
  • 1 location
High Flow Nasal Cannula With Noninvasive Ventilation

This is a prospective, randomized, unblinded trial of trauma patients in the ICU who are identified as being at a high risk to develop acute respiratory failure. We hope that this study will help the study team to identify how best to use a more aggressive respiratory treatment strategy in …

  • 26 Apr, 2022
  • 1 location
Clinical Trial of Efficacy and Safety of Raphamin in the Treatment of Coronavirus Disease 2019 in Outpatients

Multicenter double-blind placebo-controlled parallel-group randomized clinical trial of efficacy and safety of Raphamin in the treatment of coronavirus disease 2019 in outpatients.

  • 16 May, 2022
  • 8 locations
Speeding the Weaning up: Aggressive Screening Criteria and Higher Minimal Ventilatory Settings.

Hypothesis In patients with less than 4 high risk factors for reintubation excluding body mass index >30 and hypercapnia during the spontaneous breathing trial (SBT) (low and intermediate risk for extubation failure), who receive preventive therapy with high flow nasal cannula (HFNC), the use of SBT with "HIGH minimal ventilator …

  • 03 May, 2021
  • 1 location
Pragmatic Trial Examining Oxygenation Prior to Intubation (PREOXI)

Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States. One-in-ten emergency tracheal intubations is complicated by life-threatening hypoxemia. Administering supplemental oxygen prior to induction and intubation ("preoxygenation") decreases the risk …

  • 23 Jul, 2022
  • 7 locations
Venous Oxygen Saturation During ECMO Support (ECMOxygen)

SmVO2, the two more easily and systematically available variables The secondary objectives were : to evaluate the concordance of the 3 variables describing oxygen saturation

  • 30 May, 2022
  • 1 location
Trans-abdominal Fetal Pulse Oximetry; Tissue Light Scattering and Signal Integrity

The overall purpose of this study is to evaluate maternal-fetal tissue light scattering properties. The objectives of the study are: (i) integrate established mathematical principles of oxygen

Accepts healthy volunteers
  • 13 May, 2022
  • 1 location