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Found 315 clinical trials
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A Randomized Phase II Study of Perioperative mFOLFIRINOX versus Gemcitabine/nab-Paclitaxel as Therapy for Resectable Pancreatic Adenocarcinoma

A Randomized Phase II Study of Perioperative mFOLFIRINOX versus Gemcitabine/nab-Paclitaxel as Therapy for Resectable Pancreatic Adenocarcinoma

gemcitabine
adenocarcinoma
pancreatic adenocarcinoma
paclitaxel
  • 178 views
  • 23 Nov, 2020
  • 1 location
featured
A Phase II-R and A Phase III Trial Evaluating Both Erlotinib (Ph II-R) and Chemoradiation (PhIII) as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma

A Phase II-R and A Phase III Trial Evaluating Both Erlotinib (Ph II-R) and Chemoradiation (PhIII) as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma

erlotinib
adenocarcinoma
  • 178 views
  • 24 Nov, 2020
  • 1 location
A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer Compared to Nab-paclitaxel+Gemcitabine Treatment

/leucovorin (5FU/LV) plus oxaliplatin compared to nab-paclitaxel + gemcitabine treatment in improving the overall survival of patients not previously treated for metastatic pancreatic cancer.

  • 31 views
  • 26 Dec, 2020
  • 240 locations
The Randomised Study of Preoperative Radiotherapy With Consolidating Chemotherapy for Unresectable Rectal Cancer

The addition of Oxaliplatin to conventionally fractionated chemoradiation (FULV or capecitabine) is considered as standard in unresectable rectal cancer by the panel of experts. The

capecitabine
oxaliplatin
chemoradiotherapy
metastasis
  • 1 views
  • 07 Nov, 2020
  • 1 location
Trial of Preoperative Hepatic and Regional Arterial Chemotherapy (PHRAC) to Prevent Postoperative Liver Metastasis of Colorectal Cancer

The purpose of this study is to investigate whether preoperative hepatic and regional arterial chemotherapy are able to prevent liver metastasis and improve overall survival in patients receiving curative colorectal cancer resection.

adenocarcinoma of colon
adenocarcinoma
floxuridine
metastasis
liver metastasis
  • 5 views
  • 07 Nov, 2020
  • 1 location
Circulating Tumour DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation

The CIRCULATE study evaluates the adjuvant therapy in patients with colon cancer UICC stage II. The primary aim of the study is to compare the disease free survival in patients who are positive for postoperative circulating tumour DNA with vs. without capecitabine.

  • 0 views
  • 24 Jan, 2021
Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer

n the present study the neoadjuvant approach with the anti-HER2 trastuzumab and pertuzumab combined with carboplatin and paclitaxel will be used to compare the Event-Free Survival (EFS) in regimens with and without atezolizumab. Following the neoadjuvant part of the study, after surgery all patients will continue to receive trastuzumab and …

doxorubicin
residual tumor
progesterone
paclitaxel
cyclophosphamide
  • 17 views
  • 24 Jan, 2021
  • 48 locations
Effectiveness Assessment of Riluzole in the Prevention of Oxaliplatin-induced Peripheral Neuropathy.

of oxaliplatin-induced peripheral neuropathy during the Simplified FOLFOX4 adjuvant chemotherapy of stage II/III colorectal cancers.

  • 0 views
  • 16 Nov, 2020
  • 16 locations
Liposomal iRInotecan Carboplatin or oXaliplatin for Esophagogastric Cancer

This is a multi-center, open label, randomized phase II trial for patients with previously untreated metastatic or locally advanced esophagogastric cancer, using a pick the winner design to identify the best combination therapy in terms of progression free survival and neurotoxicity.

neutrophil count
gastric adenocarcinoma
cancer
leucovorin
capecitabine
  • 5 views
  • 17 Jan, 2021
  • 15 locations
Combination of Capecitabine and Oxaliplatin in Metastatic Nasopharyngeal Carcinoma

Primary: - To evaluate the efficacy of capecitabine in combination with oxaliplatin (XELOX) in terms of overall response rate (based on RECIST criteria) in patients with

platelet count
carcinoma
karnofsky performance status
metastasis
wbc count
  • 15 views
  • 07 Nov, 2020
  • 1 location