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Found 332 clinical trials
The Randomised Study of Preoperative Radiotherapy With Consolidating Chemotherapy for Unresectable Rectal Cancer

The addition of Oxaliplatin to conventionally fractionated chemoradiation (FULV or capecitabine) is considered as standard in unresectable rectal cancer by the panel of experts. The

capecitabine
oxaliplatin
metastasis
chemoradiotherapy
  • 1 views
  • 07 Nov, 2020
  • 1 location
Trial of Preoperative Hepatic and Regional Arterial Chemotherapy (PHRAC) to Prevent Postoperative Liver Metastasis of Colorectal Cancer

The purpose of this study is to investigate whether preoperative hepatic and regional arterial chemotherapy are able to prevent liver metastasis and improve overall survival in patients receiving curative colorectal cancer resection.

liver metastasis
metastasis
adenocarcinoma
adenocarcinoma of colon
oxaliplatin
  • 5 views
  • 07 Nov, 2020
  • 1 location
Donafenib for Previously Treated Metastatic Colorectal Cancer

The investigators do the clinical trial (patients with metastatic colorectal cancer treated with donafenib/placebo after failure of standard therapy) to assess efficacy and safety of donafenib in patients with metastatic colorectal cancer, progressing after all approved standard therapies.

bevacizumab
carcinoma
adenocarcinoma
oxaliplatin
irinotecan
  • 0 views
  • 03 Jun, 2021
  • 2 locations
Circulating Tumour DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation

The CIRCULATE study evaluates the adjuvant therapy in patients with colon cancer UICC stage II. The primary aim of the study is to compare the disease free survival in patients who are positive for postoperative circulating tumour DNA with vs. without capecitabine.

  • 0 views
  • 24 Jan, 2021
Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer

n the present study the neoadjuvant approach with the anti-HER2 trastuzumab and pertuzumab combined with carboplatin and paclitaxel will be used to compare the Event-Free Survival (EFS) in regimens with and without atezolizumab. Following the neoadjuvant part of the study, after surgery all patients will continue to receive trastuzumab and …

HER2
residual tumor
tubal ligation
sentinel node
paclitaxel
  • 17 views
  • 24 Jan, 2021
  • 51 locations
Combination of Capecitabine and Oxaliplatin in Metastatic Nasopharyngeal Carcinoma

Primary: - To evaluate the efficacy of capecitabine in combination with oxaliplatin (XELOX) in terms of overall response rate (based on RECIST criteria) in patients with

platelet count
metastasis
carcinoma
nasopharyngeal carcinoma
wbc count
  • 15 views
  • 07 Nov, 2020
  • 1 location
Docetaxel Plus Oxaliplatin as Therapy in Patients With Pancreatic Cancer

The purpose of this study is to test a combination-therapy of oxaliplatin and docetaxel in patients with metastatic or locally advanced adenocarcinoma of the pancreas after failure of a

drainage
metastasis
docetaxel
adenocarcinoma
pancreatic adenocarcinoma
  • 23 views
  • 07 Nov, 2020
  • 4 locations
Weekly Docetaxel Plus Cisplatin or Oxaliplatin for AGC

To evaluate the efficacy and safety of weekly administered combination of docetaxel/cisplatin and docetaxel/oxaliplatin in chemotherapy-naïve patients with advanced gastric cancer. The

docetaxel
cancer
oxaliplatin
gastric cancer
  • 6 views
  • 07 Nov, 2020
  • 1 location
LEAn Body Mass Normalization of OXaliplatin Based Chemotherapy

Cytotoxic chemotherapy is usually scaled to the body surface area (BSA), and is currently not adjusted to the body proportions of lean and fat (i.e. body composition) of individual patients. Patients with low muscle mass behave like patients "overdosed" with chemotherapy resulted in dose-limiting toxicities (e.g. dose reductions, treatment delays …

  • 3 views
  • 12 Sep, 2021
  • 11 locations
Sorafenib and FOLFIRI Regimen in 2nd Colorectal Cancer (CRC) After Failure of Oxaliplatin Treatment

advanced CRC after failure of oxaliplatin treatment.

platelet count
metastasis
adenocarcinoma
adjuvant chemotherapy
folfiri regimen
  • 5 views
  • 07 Nov, 2020
  • 1 location