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Found 620 clinical trials
Carboplatin and Paclitaxel With or Without Cediranib in Treating Women With Relapsed Ovarian Epithelial Cancer Fallopian Tube Cancer or Primary Peritoneal Cancer

RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Cediranib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth …

paclitaxel
carboplatin
ovarian epithelial cancer
tumor cells
peritoneal cancer
  • 41 views
  • 07 Nov, 2020
  • 6 locations
Efficacy of Lifestyle Intervention in BRCA1/2 Mutation Carriers

The hypothesis of this 3 year, prospective randomized multicenter efficacy trial is that a structured life-style intervention program with exercise training and mediterranean diet is effective regarding increased adherence to a mediterranean diet, reduction of body mass index, and increase of physical fitness.

  • 83 views
  • 25 Apr, 2021
  • 20 locations
Pediatric Reporting of Adult-Onset Genomic Results

The Investigators will conduct a longitudinal, mixed-methods cohort study to assess primary and secondary psychosocial outcomes among 705 MyCode pediatric participants and their parents, and health behaviors of parents whose children receive an adult- or pediatric-onset genomic result. Data will be gathered via quantitative surveys using validated measures of distress, …

cancer
heart disease
genetic counseling
  • 4 views
  • 03 Feb, 2021
  • 1 location
The Lifestyle and Empowerment Techniques in Survivorship of Gynecologic Oncology Study

This study compares traditional follow-up of gynaecological cancer patients to an alternative follow-up model. In the alternative follow-up model the patients will meet a nurse at every second consultation. The nurse will focus on psychosocial health and educate the patients in the use of a study specific smartphone-application.

cancer
ovarian cancer
carcinoma
cancer of the ovary
  • 0 views
  • 15 Jul, 2021
  • 14 locations
Family History Study on Cancer Risk

This study aims to identify the optimal method to recognize, risk stratify, and provide follow-up care for individuals at risk of hereditary cancer. The study team will conduct a Hybrid Type II comparative effectiveness-implementation trial, with a mixed methods component and process/formative evaluations for stakeholder engagement. The study team will …

familial cancer
cancer
  • 0 views
  • 25 Jan, 2021
  • 1 location
OPTimizing Treatment Focused Genetic Testing IN Cancer

This two-part randomized controlled trial aims to evaluate the impact of pre-test video education as compared to pre-test Chatbot education.

  • 0 views
  • 06 Mar, 2021
  • 1 location
Deciphering Mechanisms Underlying Cancer Immunogenicity

> Patients with any of the following tumor types may be enrolled in the trial: Head and neck cancer, Ovarian cancer, Cervical cancer, Pre-invasive CIN III cervical

ovarian cancer
cin 3
cervical lesion
lung cancer
ascites
  • 0 views
  • 26 Jan, 2021
  • 2 locations
Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

This research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer agents is safe, tolerable, and has anti-cancer activity in patients with advanced solid tumors.

carboplatin
antineoplastic
paclitaxel
parp inhibitor
  • 3 views
  • 04 Sep, 2021
  • 30 locations
COsegregation of VARiants in Panel of Genes

The aim of the COVAR project is to classify reliably a maximum of VUS of the French database in order to use them for the genetic counseling. The results obtained through this study will have a major impact on clinical management of the patients and their families conducting in some …

BRCA1/2
BRCA1
KIT
palb2
breast cancer
  • 16 views
  • 09 Aug, 2021
  • 86 locations
Dietary Fiber During Radiotherapy - a Placebo-controlled Randomized Trial

The investigators hypothesize that an increase in dietary fiber intake during radiation therapy may provide better long-term intestinal health for the cancer survivor. If the hypothesis is not correct, the increased intake may only mean an increase in acute side effects. All participants are advised to consume at least 16 …

primary cancer
bladder tumor
  • 0 views
  • 26 Jan, 2021
  • 1 location