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Found 607 clinical trials
Pediatric Reporting of Adult-Onset Genomic Results

The Investigators will conduct a longitudinal, mixed-methods cohort study to assess primary and secondary psychosocial outcomes among 705 MyCode pediatric participants and their parents, and health behaviors of parents whose children receive an adult- or pediatric-onset genomic result. Data will be gathered via quantitative surveys using validated measures of distress, …

heart disease
genetic counseling
cancer
  • 4 views
  • 03 Feb, 2021
  • 1 location
The Lifestyle and Empowerment Techniques in Survivorship of Gynecologic Oncology Study

This study compares traditional follow-up of gynaecological cancer patients to an alternative follow-up model. In the alternative follow-up model the patients will meet a nurse at every second consultation. The nurse will focus on psychosocial health and educate the patients in the use of a study specific smartphone-application.

ovarian cancer
carcinoma
cancer
cancer of the ovary
  • 0 views
  • 25 Jan, 2021
  • 12 locations
Family History Study on Cancer Risk

This study aims to identify the optimal method to recognize, risk stratify, and provide follow-up care for individuals at risk of hereditary cancer. The study team will conduct a Hybrid Type II comparative effectiveness-implementation trial, with a mixed methods component and process/formative evaluations for stakeholder engagement. The study team will …

cancer
familial cancer
  • 0 views
  • 25 Jan, 2021
  • 1 location
OPTimizing Treatment Focused Genetic Testing IN Cancer

This two-part randomized controlled trial aims to evaluate the impact of pre-test video education as compared to pre-test Chatbot education.

  • 0 views
  • 06 Mar, 2021
  • 1 location
Deciphering Mechanisms Underlying Cancer Immunogenicity

> Patients with any of the following tumor types may be enrolled in the trial: Head and neck cancer, Ovarian cancer, Cervical cancer, Pre-invasive CIN III cervical

solid tumour
lung carcinoma
cancer of the ovary
cancer
lung cancer
  • 0 views
  • 26 Jan, 2021
  • 2 locations
Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

This research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer agents is safe, tolerable, and has anti-cancer activity in patients with advanced solid tumors.

  • 0 views
  • 16 May, 2021
  • 15 locations
Dietary Fiber During Radiotherapy - a Placebo-controlled Randomized Trial

The investigators hypothesize that an increase in dietary fiber intake during radiation therapy may provide better long-term intestinal health for the cancer survivor. If the hypothesis is not correct, the increased intake may only mean an increase in acute side effects. All participants are advised to consume at least 16 …

primary cancer
bladder tumor
  • 0 views
  • 26 Jan, 2021
  • 1 location
Identifying and Caring for Individuals With Inherited Cancer Syndrome

. Researchers hope to learn the value of providing broad, public-wide testing for high risk cancer types (like hereditary breast and ovarian cancer or Lynch syndromes) instead of only testing people whose

  • 0 views
  • 13 Feb, 2021
  • 2 locations
A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors

> This study will enroll 7 tumor-specific cohorts: urothelial bladder cancer, biliary tract cancer, cervical cancer, endometrial cancer, ovarian cancer, pancreatic cancer, and rare tumors.

  • 0 views
  • 30 Apr, 2021
  • 83 locations
A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms

The primary goal of this Phase 1 study is to characterize the safety and tolerability of MGD013 and establish the maximum tolerated dose (MTD) of MGD013. Pharmacokinetics (PK), immunogenicity, pharmacodynamics (PD), and the anti-tumor activity of MGD013 will also be assessed.

solid tumour
HER2
measurable disease
erbb2
cancer
  • 534 views
  • 17 Feb, 2021
  • 70 locations