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Found 602 clinical trials
A Study of Intra-operative Imaging in Women With Ovarian Cancer

The purpose of this study is to find out whether using the PINPOINT imaging system intra-operatively can reduce the risk of anastomotic leaks and other complications after surgery for ovarian

  • 0 views
  • 13 May, 2021
  • 7 locations
Early Detection of High Grade Ovarian Cancer Using Uterine Lavage EHUD Study and Duplex Sequencing

In Phase I the sponsor will systematically test conditions for lavage filtration that increase tumor cell fraction without reducing tumor mutation yield. The Sponsor will also transition all lavages to luteal phase timing, when endometrial shedding is least. In Phase II the Sponsor will examine our data in context of …

  • 0 views
  • 07 Apr, 2021
  • 9 locations
Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery

), for the treatment of subjects with newly diagnosed advanced ovarian cancer who have undergone optimal debulking.

adenocarcinoma
renal function tests
blood transfusion
carboplatin/paclitaxel
cancer of the ovary
  • 25 views
  • 31 Jul, 2021
  • 83 locations
TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

ovarian cancer incidence.

ovarian cancer
BRCA2
oophorectomy
cancer
rad51c
  • 0 views
  • 09 May, 2021
  • 14 locations
A Study of Fluzoparib Apatinib Versus Placebo Maintenance Treatment in Patients With Advanced Ovarian Cancer Following Response on First-Line Platinum-Based Chemotherapy

with Stage III or IV ovarian cancer. Patients must have completed first-line platinum based regimen with Complete Response (CR) or Partial Response (PR). The study contains a Safety Lead-in Phase in

ovarian cancer
apatinib
cancer
cancer chemotherapy
measurable disease
  • 0 views
  • 25 Jan, 2021
  • 1 location
Lavage of the Uterine Cavity for the Diagnosis of Serous Tubal Intraepithelial Carcinoma

The current study aims at answering the scientific question, whether exfoliated cells from STICs get transported into the uterine cavity via the fallopian tube, and whether it is possible to detect those cells in the lavage fluid from the uterine cavity and proximal fallopian tubes. To address this question, the …

ovarian cancer
carcinoma
cancer
BRCA1/2
cancer of the ovary
  • 95 views
  • 10 Apr, 2021
  • 17 locations
Atezolizumab With Bevacizumab and Chemotherapy vs Bevacizumab and Chemotherapy in Early Relapse Ovarian Cancer

This is a phase III, randomized, partially blinded, multicenter trial to evaluate the efficacy and safety of atezolizumab plus bevacizumab and chemotherapy compared to placebo plus bevacizumab and chemotherapy in patients with recurrent ovarian-, fallopian tube, or primary peritoneal cancer with 1st or 2nd relapse within 6 months after platinum …

  • 65 views
  • 02 Aug, 2021
  • 156 locations
Platinum-based Chemotherapy With Atezolizumab and Niraparib in Patients With Recurrent Ovarian Cancer

Atezolizumab in this study is expected to have a positive benefit-risk profile for the treatment of patients with platinum-sensitive relapse of ovarian cancer. Of interest, atezolizumab is being

  • 7 views
  • 26 Jan, 2021
  • 89 locations
A Study of ZN-c3 in Patients With Platinum-Resistant Ovarian Cancer

This is a Phase 1b open-label, multicenter study, evaluating the safety, tolerability, preliminary clinical activity, pharmacokinetics (PK), and pharmacodynamics of ZN-c3 in combination with other drugs.

carboplatin
cancer of the ovary
ovarian cancer
doxorubicin
  • 0 views
  • 03 Aug, 2021
  • 24 locations
Carboplatin and Paclitaxel With or Without Cediranib in Treating Women With Relapsed Ovarian Epithelial Cancer Fallopian Tube Cancer or Primary Peritoneal Cancer

RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Cediranib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth …

fallopian tube
peritoneal cancer
tumor cells
ovarian epithelial cancer
carboplatin
  • 41 views
  • 07 Nov, 2020
  • 6 locations