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Found 609 clinical trials
Transvaginal Ultrasonography as a Screening Method for Ovarian Cancer

This is a large, prospective, single-arm cohort study of transvaginal ultrasonographic screening for ovarian cancer in intermediate to high-risk women from Kentucky. Detection of ovarian

breast cancer
cancer of the ovary
  • 0 views
  • 25 Jan, 2021
  • 1 location
A Study to Compare Two Surgical Procedures in Women With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

This trial studies how well two surgical procedures (bilateral salpingectomy and bilateral salpingo-oophorectomy) work in reducing the risk of ovarian cancer for women with BRCA1 mutations

hysterectomy
fallopian tube
ovarian cancer
cancer
cancer antigen 125
  • 52 views
  • 03 Feb, 2021
  • 91 locations
MAintenance Therapy With Aromatase Inhibitor in Epithelial Ovarian Cancer (MATAO)

high and low grade epithelial ovarian cancer (including fallopian tube and primary peritoneal cancer) and subsequent primary treatment surgery and chemotherapy. Half of the participants will receive to

  • 0 views
  • 28 Feb, 2021
  • 18 locations
Hysterectomy and OPPortunistic SAlpingectomy

>implies reduced risk of subsequent ovarian cancer Randomization and follow-up will be conducted within national registers.

laparotomy
cancer of the ovary
  • 10 views
  • 26 Jan, 2021
  • 1 location
Study Evaluating the Efficacy of Maintenance Olaparib and Cediranib or Olaparib Alone in Ovarian Cancer Patients

ICON 9 will assess the efficacy, safety and tolerability of maintenance olaparib in combination with cediranib compared to maintenance olaparib alone following a response to platinum-based chemotherapy in women with relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer. Prognostic and predictive factors will be studied from tumour and blood samples.

metastasis
tumor debulking
measurable disease
bevacizumab
cancer of the ovary
  • 392 views
  • 25 Mar, 2021
  • 43 locations
Effect of Tumor Treating Fields (TTFields 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)

of recurrent ovarian cancer . The device is an experimental, portable, battery operated device for chronic administration of alternating electric fields (termed TTFields or TTF) to the region of the

carcinoma
cancer of the ovary
recurrent ovarian cancer
fallopian tube
paclitaxel
  • 273 views
  • 08 Apr, 2021
  • 126 locations
Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women

The goal of this clinical research study is to evaluate a method involving a blood test, called CA-125, that may be helpful in the early detection of ovarian cancer in women who are at low risk

cancer antigen 125
cancer of the ovary
cancer chemotherapy
  • 1609 views
  • 23 Jan, 2021
  • 11 locations
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib

The rationale of the ROSY-O study is to continue to provide study treatment for patients who have participated in a parent study with olaparib and who are continuing to derive clinical benefit from treatment at the end of such studies, as judged by the Investigator.

olaparib
  • 0 views
  • 06 Apr, 2021
  • 48 locations
Evaluating the Performance of Morphology Index in Surgical Decision-Making for Ovarian Tumors

distinguishing benign from malignant ovarian tumors. If there is no change in the detection of true positive cases, the result will be an increase in the positive predictive value of ovarian cancer screening.

breast cancer
cancer of the ovary
  • 7 views
  • 25 Jan, 2021
  • 1 location
Early Detection of High Grade Ovarian Cancer Using Uterine Lavage EHUD Study and Duplex Sequencing

In Phase I the sponsor will systematically test conditions for lavage filtration that increase tumor cell fraction without reducing tumor mutation yield. The Sponsor will also transition all lavages to luteal phase timing, when endometrial shedding is least. In Phase II the Sponsor will examine our data in context of …

  • 0 views
  • 07 Apr, 2021
  • 9 locations