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Found 595 clinical trials
A Training Set for the HRD Model in EOC

A homologous recombination deficiency (HRD) scoring model based on loss of heterozygosity (LOH) is little explored in epithelial ovarian cancer (EOC) patients. This study would recruit 200

  • 0 views
  • 27 Jan, 2021
  • 1 location
Analysis of the Clinical Experience With Rucaparib in the Rucaparib Access Program (RAP) in Spain - A GEICO Study

The study consists of a retrospective observational, multicenter study in which the fundamental exposure factor being investigated is a drug (rucaparib). A clinical database will be built including clinical data in three scenarios of rucaparib treatment: (1) platinum-sensitive BRCA-mutated patients after progression, (2) maintenance therapy in patients after a platinum-sensitive …

rucaparib
peritoneal cancer
  • 0 views
  • 25 Jan, 2021
  • 20 locations
International Ovarian & Testicular Stromal Tumor Registry

been found to be associated with a lung cancer of early childhood called pleuropulmonary blastoma (PPB). The cause of these ovarian tumors is unknown. DICER1 mutations are seen in the majority of

  • 0 views
  • 22 Jan, 2021
  • 1 location
Identification of Biomarkers Associated With Human Hepatocellular Carcinoma by SELDI

, bladder cancer, ovarian cancer, lung cancer, colon cancer, breast cancer and pancreatic cancer. In this current project we will apply the SELDI technique to identify the HCC biomarkers

prothrombin
cancer
hepatocellular carcinoma
alpha-fetoprotein
hepatitis
  • 3 views
  • 07 Nov, 2020
  • 1 location
International PPB/DICER1 Registry

Pleuropulmonary blastoma (PPB) is a rare malignant neoplasm of the lung presenting in early childhood. Type I PPB is a purely cystic lesion, Type II is a partially cystic, partially solid tumor, Type III is a completely solid tumor. Treatment of children with PPB is at the discretion of the …

initial diagnosis
sarcoma
cancer
solid tumor
  • 37 views
  • 23 Jan, 2021
  • 1 location
Paclitaxel Therapeutic Drug Monitoring in Cancer Patients

The goals of this prospective, observational cohort study are to determine the feasibility of implementing paclitaxel therapeutic drug monitoring for cancer patients and explore the relationship between paclitaxel drug exposure and the development of neuropathic symptoms. This trial studies if paclitaxel can be consistently measured in the blood of patients …

topotecan
gemcitabine
invasive breast cancer
pazopanib
paclitaxel
  • 0 views
  • 28 Jan, 2021
  • 1 location
Rapid Autopsy and Procurement of Cancer Tissue

after death. To do so, they will arrange to provide inpatient hospice care for people with non-small cell lung cancer, ovarian cancer, bladder cancer, or patients who have been treated with adoptive

incurable disease
stage iv non-small cell lung cancer
cancer
thymoma
ovarian cancer
  • 44 views
  • 24 Feb, 2021
  • 1 location
Cohort of Patients With Pelvic Gynecological Cancer: Constitution of a Collection of Biological Samples With Radioclinic Characterization

adapted to this biology is currently in full development. For example, sequencing ovarian tumors can select patients who can benefit from anti-PARP therapy. There is therefore a need for patients to have

ovarian cancer
  • 2 views
  • 25 Jan, 2021
  • 1 location
Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer Moonshot Study

This trial studies the genetic analysis of blood and tissue samples from patients with cancer that has spread to other anatomic sites (advanced) or is no longer responding to treatment. Studying these samples in the laboratory may help doctors to learn how genes affect cancer and how they affect a …

targeted therapy
investigational drug
biospecimen collection
recurrent disease
cancer
  • 38 views
  • 16 Feb, 2021
  • 111 locations
Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes

This study examines at-home monitoring of patient-generated phsyiologic health data and patient-reported outcomes. Patient-generated health data using at-home monitoring devices and smart device applications are used more and more to measure value and quality in cancer care. This trial may show whether at-home monitoring programs can improve the care of …

primary cancer
cancer
cancer care
cancer treatment
  • 0 views
  • 25 Jan, 2021
  • 1 location