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Found 621 clinical trials
ICG-Enabled Mapping of Ovarian Sentinel Lymph Nodes: A Feasibility Study

The purpose of this study is to find out how well ovarian sentinel lymph nodes (SLNs) can be identified with indocyanine green (ICG) dye during risk-reducing ovarian surgery.

intraperitoneal chemotherapy
cancer of the ovary
fallopian tube
laparotomy
  • 8 views
  • 27 Jan, 2021
  • 8 locations
Laboratory Study of Cancer & Immune Cells in Ascites Fluid of Ovarian Cancer Patients to Test Alternative Therapies

Ascites samples from women undergoing surgery for ovarian cancer will be collected for use in translational research.

cancer of the ovary
surgery for ovarian cancer
fallopian tube
primary peritoneal carcinoma
cytoreductive surgery
  • 22 views
  • 21 May, 2021
  • 1 location
Data and Specimen Bank of Patients Diagnosed With and at High-risk for Gynecologic Cancers

The purpose of this project is to establish a bank at UVa of tampon samples, cervical swabs, blood, associated tumor specimens that would otherwise be discarded, and relevant medical data from consenting patients that have suspected and/or confirmed gynecological cancer diagnoses. The specimens collected will be saved for analysis on …

breast cancer
ascites
  • 3 views
  • 24 Jan, 2021
  • 1 location
Development of a Decision Aid to Facilitate Ovarian Cancer Patient's Choices Regarding Biomarker CA125

In 2015 the Danish Health authorities initiated major changes in the national follow-up (FU) program for ovarian cancer patients. The new FU program argues that there is no effect of routine

cancer antigen 125
cancer of the ovary
peritoneal cancer
fallopian tube
  • 1 views
  • 12 Sep, 2021
  • 1 location
Niraparib as Maintenance Treatment in Platinum Responsive Ovarian Cancer Patients: a Real Life Study

This is an observational phase IV study evaluating Niraparib as maintenance treatment in patients with platinum sensitive, platinum responsive, recurrent ovarian cancer in a real life setting

niraparib
cancer of the ovary
platinum-based chemotherapy
fallopian tube
cancer chemotherapy
  • 0 views
  • 02 Sep, 2021
  • 1 location
Immuno Monitoring in Patient With Epithelial Ovarian Cancer Eligible to PARP Inhibitors

This study concerns the creation of a biological collection (blood samples) in patients with Epithelial Ovarian Cancer in in order to describe the immune response with PARP inhibitors.

ovarian epithelial carcinoma
niraparib
cancer of the ovary
olaparib
  • 0 views
  • 03 Jun, 2021
  • 2 locations
Olaparib Real-world Utilization and Clinical Outcomes in France Italy and the UK

This is a retrospective observational medical records review study of BRCA mutated advanced (FIGO stage III-IV) ovarian cancer patients who received first dose maintenance olaparib in 1L setting

ovarian epithelial carcinoma
cancer of the ovary
platinum-based chemotherapy
cancer chemotherapy
olaparib
  • 0 views
  • 02 Sep, 2021
  • 21 locations
Effects of Cytotoxic Chemotherapy and PARP Inhibition on the Genomic Contexture of Ovarian Cancer

the genomic characteristics of ovarian tumors before and after treatment with classic neoadjuvant chemotherapy (NACT) and with the more recently approved PARP inhibitor olaparib.

  • 0 views
  • 16 Apr, 2021
  • 1 location
Evaluation of the Predictive Value of Blood Levels of Angiopoietin 1 and Endothelial Internal Tunica Cell Kinase 2 in Patients With Ovarian Cancer Treated With Chemotherapy Associated to Bevacizumab

This is a monocentric prospective observational pilot study of translational research in women with advanced ovarian epithelial cancer. The main purpose of this study is to evaluate the predictive value of response to treatment with bevacizumab of the circulating levels of Ang1, Tie2 and VEGF before start of therapy. Secondary …

ovarian epithelial cancer
ovarian epithelial carcinoma
cancer of the ovary
ovarian carcinoma
cancer chemotherapy
  • 0 views
  • 12 Jun, 2021
  • 1 location
Genes Contributing to Hereditary Ovarian Cancer in Women and BRCA1/2 Wildtype Families

ovarian cancer susceptibility genes. The hypothesis is at least one third of hereditary ovarian carcinoma families wildtype for BRCA1/2 can be solved using an updated version of BROCA (BROCA-HR) that

BRCA1/2
ovarian epithelial carcinoma
cancer of the ovary
ovarian carcinoma
BRCA1
  • 0 views
  • 17 Jul, 2021
  • 1 location