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Found 593 clinical trials
Study Looking at Biomarkers in Ovarian Cancer

This is a sample study that will collect biological samples (blood, tumor tissue, ascites, and/or other fluids) from gynecological cancer patients for biomarker research. In addition, the results of the testing done on the samples will be given to the participant's treating physician who may use the information to guide …

cancer
ovarian cancer
  • 20 views
  • 26 Jan, 2021
  • 5 locations
Ribociclib and Letrozole Treatment in Ovarian Cancer

The study evaluates the response to treatment with Ribociclib and Letrozole in patients with low grade serous cancer of the ovary, fallopian tube or peritoneum.

  • 26 views
  • 03 Feb, 2021
  • 26 locations
Phase 3 Trial Evaluating Hyperthermic Intraperitoneal Chemotherapy in Upfront Treatment of Stage IIIC Epithelial Ovarian Cancer

unresectable epithelial tubal/ovarian cancer with partial or complete response after 3 cycles of 1st line chemotherapy (CBDCA +Paclitaxel).

cancer chemotherapy
ovarian epithelial carcinoma
cytoreductive surgery
intraperitoneal chemotherapy
carboplatin
  • 67 views
  • 08 Nov, 2020
  • 2 locations
Neoadjuvant Chemotherapy in Advanced Epithelial Ovarian Cancer (EOC): A Phase III Randomized Study

To determine the impact of Neoadjuvant chemotherapy on surgical debulking rate, overall and disease-free survival and quality of life (QOL) in patients with advanced EOC.

ovarian carcinoma
ovarian cancer
carcinoma
cancer
ovarian epithelial carcinoma
  • 19 views
  • 07 Nov, 2020
  • 1 location
A Phase I/II Study of Paclitaxel Plus Carboplatin Plus Vorinostat in Recurrent Ovarian Cancer

TITLE:A Phase II non-comparative study of paclitaxel plus carboplatin in combination with Vorinostat in patients with advanced, recurrent epithelial ovarian cancer. INDICATION:Second-line

platinum-sensitive ovarian carcinoma
doxorubicin
topotecan
carcinoma
cancer antigen 125
  • 10 views
  • 07 Nov, 2020
  • 1 location
Trial of Active Immunotherapy With Globo H-KLH (OPT-822/821) in Women Who Have Non-Progressive Ovarian Cancer

The purpose of this study is to evaluate the effect of OPT-822/OPT-821 on improving Progression-Free Survival (PFS) in subjects who have non-progressive epithelial ovarian, fallopian tube, or primary peritoneal cancer after cytoreductive surgery and platinum-based chemotherapy as initial treatment for primary disease or as salvage treatment for first relapse.

primary peritoneal carcinoma
peritoneal cancer
cytoreductive surgery
fallopian tube
platinum-based chemotherapy
  • 36 views
  • 07 Nov, 2020
  • 1 location
Adjuvant Whole Abdominal Intensity Modulated Radiotherapy (IMRT) for High Risk Stage FIGO III Patients With Ovarian Cancer

The prognosis for patients with advanced epithelial ovarian cancer remains poor despite aggressive surgical resection and platinum-based chemotherapy. More than 60% of patients will

immunostimulant
carboplatin/paclitaxel
residual tumor
ovarian cancer stage
platinum-based chemotherapy
  • 46 views
  • 07 Nov, 2020
  • 1 location
Gemcitabine Paclitaxel Ifosfamide and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors

RATIONALE: Drugs used in chemotherapy, such as gemcitabine, paclitaxel, ifosfamide, and cisplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects …

ifosfamide
germ cell tumor
tumor cells
pegfilgrastim
filgrastim
  • 32 views
  • 07 Nov, 2020
  • 1 location
Neoadjuvant Chemotherapy With Carboplatin and Docetaxel in Patients With Advanced Ovarian Cancer-Prospective Randomized Phase II Clinical Trial

The purpose of this study is to evaluate response to neoadjuvant chemotherapy by imaging and observation of anatomical and biological indicators (i.e. ascites or continuous measurement of tumor marker CA 125). Furthermore the optimal number of preoperative administered cycles of combination chemotherapy with carboplatin and docetaxel should be determined.

carboplatin
ascites
tumor markers
combination chemotherapy
cancer antigen 125
  • 2 views
  • 07 Nov, 2020
  • 1 location
  • 0 views
  • 14 Feb, 2021
  • 1 location