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Found 282 clinical trials
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Advance Care Planning: Promoting Effective and Aligned Communication in the Elderly

In this research study, the investigators are working to help oncologists better serve patients by delivering more patient-centered, goal-concordant care that may improve health care delivery. It is expected that about 12,000 people will take part in this research study, 11,550 of these patients, the vast majority, will be included …

  • 0 views
  • 13 Nov, 2021
  • 3 locations
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Imaging Biomarkers of Lymphatic Dysfunction

Persons with secondary arm and/or upper quadrant lymphedema following cancer therapies commonly are prescribed complete decongestive therapy as a course of management of their lymphedema. The investigators will perform a repeated-measures cross-over trial to test the hypothesis that mobilization of protein enriched hardened tissue using graded negative pressure therapy in …

  • 0 views
  • 17 Oct, 2021
  • 1 location
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Exercise and Tumor Blood Flow in Breast Cancer Patients

This research aims at investigating tumor blood flow response to acute exercise in human cancer patients. It is hypothesized and expected that acute exercise increases tumor blood flow, which could plausibly increase the efficacy of cancer treatment.

cancer treatment
  • 0 views
  • 25 Jan, 2021
  • 1 location
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Micronized Purified Flavonoid- Fraction (MPFF) in the Management of Radiation Proctitis

national and multi-center trial for medical therapy of chronic radiation proctitis inducing anorectal bleedings

  • 0 views
  • 26 Jan, 2021
  • 20 locations
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Exercise and Tumor Blood Flow

This research aims at investigating tumor blood flow response to acute exercise in human cancer patients. It is hypothesized and expected that acute exercise increases tumor blood flow, which could plausibly increase the efficacy of cancer treatment.

  • 0 views
  • 18 Feb, 2021
  • 1 location
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Urtica Comp. Gel for Prevention and Therapy of Radiation Dermatitis

A randomized controlled trial comparing Urtica comp. gel (Swissmedic listed medication in the category of "Anthroposophic Medication without Indication") against standard skin care, examining its effect in prevention and treatment of radiation dermatitis in breast cancer patients under Radiation therapy.

  • 0 views
  • 07 Oct, 2021
  • 2 locations
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Adjuvant Dendritic Cell-immunotherapy Plus Temozolomide in Glioblastoma Patients

In this phase I/II trial, the primary objective is to determine overall and progression-free survival of patients with newly diagnosed glioblastoma when autologous Wilms' tumor 1 (WT1) messenger (m)RNA-loaded dendritic cell (DC) vaccination is added to adjuvant temozolomide maintenance treatment following (sub)total resection and temozolomide-based chemoradiation.

  • 23 views
  • 28 Jan, 2021
  • 1 location
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Trial of Pembrolizumab in Cancer of Unknown Primary

Abbreviated Title : CUPem Clinical Indication : A Phase II, Two-Stage, Trial of Pembrolizumab in Cancer of unknown primary Trial Type : Single Arm, non-randomised; Two-stage; Hypothesis generating Type of control : None Route of administration : IV Trial Blinding : N/A Treatment Groups :Two cohorts: (i) First Cohort: One …

  • 0 views
  • 22 Jan, 2021
  • 1 location
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RAdiotherapy for Metastatic Spinal Cord Compression With Increased Radiation dosES

This clinical study aims to investigate whether high-precision radiotherapy, as supposed, leads to a better control of the irradiated spinal cord metastases when compared to conventional radiotherapy. This means that a progression or recurrence of motor deficits (weakness) of the legs following radiotherapy can be avoided more effectively. Furthermore, the …

  • 0 views
  • 11 May, 2021
  • 2 locations
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Next Generation Sequencing-Based Stratification of Front Line Treatment of HighGrade Neuroendocrine Carcinoma

PRECISION-NEC is a single-center, open-label, pilot feasibility study of molecularly defined subtypes of metastatic high-grade neuroendocrine carcinoma (HG-NEC). The hypothesis is that HG-NEC (excluding small cell carcinoma) can be segregated based on mutational analysis and that next generation sequencing (NGS)-based assignment of therapy is feasible and will potentially improve the …

  • 0 views
  • 27 Jan, 2021
  • 1 location