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Found 282 clinical trials
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Developing a Test for the Detection of Ovarian Cancer

The study aims to develop a test for early detection of ovarian cancer using DNA from a growth involving the ovary found in a washing of the uterus (womb), and proteins found in the blood. The samples of the wash and the blood will be taken before surgery. After surgery, …

  • 0 views
  • 24 Mar, 2021
  • 6 locations
None
An Analysis to Estimate Febrile Neutropenia (FN) in Patients Receiving Udenyca

This is a multicenter, prospective, observational cohort registry in subjects receiving myelosuppressive chemotherapy for a non-myeloid malignancy who are considered to be at high risk for developing febrile neutropenia (FN).

  • 0 views
  • 27 Jan, 2021
  • 3 locations
None
Phenotype and Prognosis of Patients With Breast Cancer and Pathogenic Variants of TP53

We did a prospective and retrospective cohort study of patients with a documented pathogenic or likely pathogenic variants of TP53 were identified using blood DNA colection and breast cancer diagnosis by histological confirmation, between 1999 and 2021. All patients were followed by the Hereditary Group of a single cancer center …

invasive carcinoma
TP53
carcinoma
  • 0 views
  • 30 Jul, 2021
  • 1 location
None
Can Staging Magnetic Resonance Imaging (MRI) Features Prognosticate Patients Presenting With Endometrial Cancer?

Aim: Assess the value of MRI features in predicting prognosis in patients with endometrial cancer This study will examine the MRI features of women with confirmed endometrial cancer to see if textural features can prognosticate patients.

cancer
hysterectomy
  • 7 views
  • 17 Feb, 2021
  • 1 location
None
Evaluation of Clinical Radiomics and Molecular Features of Lung Metastasis in PDAC Patients (LUMACA Trial)

The aim of this study is the characterization from epidemiological, radiomics and molecular point of view of lung metastasis of patients at beginning affected by pancreatic adenocarcinoma (PDAC), which after the resection of primitive tumor have met with initial recurrence of the disease exclusively at the lung level.

pdac
metastasis
  • 0 views
  • 24 Jan, 2021
  • 4 locations
None
Artificial Intelligence for Prostate Cancer Treatment Planning

This project's goal is to develop and test an application that uses Artificial Intelligence (AI) to improve consistency and quality of Radiation Treatment (RT) plans for prostate cancer. By understanding expert planner preferences in structure contouring and treatment planning, and combining this framework with planning data and outcomes amassed in …

gonadotropin
antiandrogen therapy
cancer
prostate specific antigen
adenocarcinoma of prostate
  • 0 views
  • 27 Oct, 2021
  • 1 location
None
A Prospective Study of Low-dose Decitabine Combined With COP Regimen in the Treatment of Relapsed and Refractory DLBCL

Decitabine is a cytosine analogue and is a specific DNA methyltransferase (DNMT) inhibitor. It directly inhibits DNMT by phosphorylating DNA and inhibits DNMT, thereby reversing DNA methylation and inducing tumor cells to Normal cell differentiation or induction of tumor cell apoptosis.Diffuse large B-cell lymphoma (DLBCL) is the most common pathological …

  • 0 views
  • 22 Jan, 2021
  • 1 location
None
Single-cell Sequencing and Establishment of Models in Neuroendocrine Neoplasm

The aim of this study is to use single-cell sequencing technology to explore neuroendocrine neoplasm (NEN) molecular biological characteristics, tumor heterogeneity and cell subtypes. Besides. NEN models are constructed for basic research, including primary cell lines, organoids, and animal models.

  • 0 views
  • 30 Sep, 2021
None
Rapid Autopsy and Procurement of Cancer Tissue

Background Individuals with cancer of the lung, chest cavity, ovary, or bladder, as well as patients who have been treated with adoptive cell therapy unfortunately commonly succumb to their disease. Some agree to donate their bodies to cancer research that may help the medical community better understand these diseases. Studies …

lung carcinoma
cancer
thymoma
lung cancer
stage iv non-small cell lung cancer
  • 44 views
  • 12 Sep, 2021
  • 1 location
None
WGA in Platinum-refractory HNSCC Underwent Nivolumab

To choose a subgroup who could clearly benefit from Nivolumab, we are proposing a prospective observational study. Whole-genome study (WGS) analysis will be performed on archived cancer tissues from patients who were (1) cisplatin-refractory and subsequently (2) received Nivolumab (at least 4 doses) and (3) had completed imaging response evaluation …

nivolumab
cancer
  • 1 views
  • 22 Jan, 2021
  • 1 location