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Found 54 clinical trials
Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease

helper cell that can be removed from donated umbilical cord blood tissue and grown into many different cell types that can be used to treat cancer and other disease, such as graft versus host disease

cell transplantation
cancer
graft versus host disease
donor lymphocyte infusion
acute graft versus host disease
  • 0 views
  • 21 Jul, 2022
  • 1 location
An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEE

To assess the long-term safety and tolerability of XEN496 in pediatric subjects with KCNQ2 developmental and epileptic encephalopathy (KCNQ2-DEE) who had participated in the primary study (XPF-009-301).

ezogabine
  • 0 views
  • 27 Oct, 2021
  • 1 location
Remote Ischemic Conditioning for the Treatment of Intracerebral Hemorrhage (RICH-2)

Intracerebral hemorrhage (ICH) results from the rupture of small vessels damaged by chronic hypertension, amyloid angiopathy or other disease. Currently, ICH has been a devastating type of

  • 0 views
  • 25 Jul, 2022
  • 7 locations
Diminish Chemotherapy Related Side Effects Through Patient Education (D-CRSE)

health system. If this intervention is found to be useful and impactful, it can be further utilized within the Cancer Institute by other disease teams, by other Penn State institutions, or by other

  • 0 views
  • 25 Mar, 2022
  • 1 location
Safety and Modulation of ABCC9 Pathways by Nicorandil for the Treatment of Hippocampal Sclerosis of Aging (SMArT-HS)

is not the only form of dementia and that beginning to turn attention to other disease states is critically important in order to alleviate this burden on the elderly population today This proposal

alzheimer's disease
dementia
  • 1 views
  • 25 Mar, 2022
  • 1 location
Effects of Brain Stimulation on Higher-Order Cognition

research in order to understand brain function in healthy individuals and individuals with schizophrenia. This study is not intended to diagnose, cure or treat schizophrenia or any other disease.

schizoaffective disorder
antipsychotics
clozapine
Accepts healthy volunteers
transcranial direct current stimulation
  • 40 views
  • 25 Mar, 2022
  • 1 location
The Effects of Whole-body Exercise to Improve Swallowing Function in Older Adults With Dementia

Swallowing impairment (dysphagia) is extremely common in older adults living with dementia due to age-related changes in swallowing and other disease-specific impairments. Dysphagia is commonly

dementia
aerobic exercise
malnutrition
  • 0 views
  • 04 May, 2022
  • 1 location
XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy

To investigate the potential antiseizure effects of adjunctive XEN496 (ezogabine) compared with placebo in children with KCNQ2 Developmental and Epileptic Encephalopathy (KCNQ2-DEE).

ketogenic diet
electroencephalogram
ezogabine
seizure
tonic
  • 8 views
  • 31 Oct, 2021
  • 10 locations
Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia

(GABA; Aim 3) that is important to cognitive functioning and may be disrupted in people with schizophrenia. Although this study is not intended to diagnose, cure or treat schizophrenia or any other

schizoaffective disorder
antipsychotics
clozapine
Accepts healthy volunteers
transcranial direct current stimulation
  • 6 views
  • 11 Aug, 2022
  • 1 location
Effects of Remote Monitoring of Patients With Heart Failure Based on Smartphone Application (ERICA-HF)

CHF is a most wild-spread and prognostically poor outcome most of cardiovascular and other disease. Despite of significant progress in treatment of CHF for the last years, death from this

depression
medical therapy
chronic heart failure
infarct
myocardial infarction
  • 0 views
  • 03 May, 2022
  • 1 location