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Found 55 clinical trials
Featured trial
The Axcelsius Study: A Study of ONO-7475 in Patients with Acute Leukemias

Food and Drug Administration (FDA) or any other regulatory drug agency to use for AML or any other disease. Study participants in this study will take the study drug with venetoclax, an approved drug

induction chemotherapy
leukemia
cancer
myeloid leukemia
acute leukemia
  • 21 views
  • 11 Jan, 2022
  • 4 locations
Simulation-Free Hippocampal-Avoidance Whole Brain Radiotherapy Using Diagnostic MRI-Based and Cone Beam Computed Tomography-Guided On-Table Adaptive Planning in a Novel Ring Gantry Radiotherapy Device

radiation treatment positioning, etc.) while the patient is on the treatment table at fraction one using adaptive radiation planning. Adaptive radiotherapy is standard-of-care practice for other disease

  • 0 views
  • 23 Mar, 2022
  • 1 location
Different Anesthetic Strategies on Postoperative Cognitive Function and Delirium in Patients Undergoing Cardiac Surgery

This is a prospective, multi-center, double-blind, randomized clinical trials.

coronary artery bypass graft
anesthesia
heart surgery
cardiac operation
  • 5 views
  • 07 Mar, 2022
  • 3 locations
Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery (TRICS-IV)

TRICS-IV is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in moderate to high risk patients who are 65 years of age or younger undergoing cardiac surgery on cardiopulmonary bypass, using a superiority trial design.

cardiopulmonary bypass
  • 0 views
  • 12 Mar, 2022
  • 6 locations
Validation of the Wisconsin Stone-QOL

within patients related to stone interventions and other disease-specific outcomes by answering the question, "Is the Wisconsin Stone-QOL sensitive to changes in stone-related outcomes within

nephrolithiasis
  • 19 views
  • 29 Nov, 2021
  • 1 location
An Open-Label Extension of the Study XEN496 in Children With KCNQ2 Developmental and Epileptic Encephalopathy (EPIK-OLE)

To assess the long-term safety and tolerability of XEN496 in pediatric subjects with KCNQ2 developmental and epileptic encephalopathy (KCNQ2-DEE) who had participated in the primary study (XPF-009-301).

ezogabine
  • 0 views
  • 15 Sep, 2022
  • 12 locations
A Phase 3 Study of Adjunctive XEN496 in Pediatric Subjects With KCNQ2 Developmental and Epileptic Encephalopathy (EPIK)

To investigate the potential antiseizure effects of adjunctive XEN496 (ezogabine) compared with placebo in children with KCNQ2 Developmental and Epileptic Encephalopathy (KCNQ2-DEE).

stroke
seizure
tonic
ketogenic diet
ezogabine
  • 8 views
  • 16 Sep, 2022
  • 13 locations
Fibrinogen Replacement to Prevent Intracranial Haemorrhage in Ischemic Stroke Patients After Thrombolysis (FibER) (FibER)

Fibrinogen replacement could prevent haemorrhagic complications in ischemic stroke patients with secondary post-rtPA hypofibrinogenemia

stroke
fibrinogen
  • 0 views
  • 20 Apr, 2022
  • 1 location
Genetic Testing in Young Adults With Cancer Study

The overarching goal of our research is to define an evidence-based, sustainable approach to identifying and managing genetic risk among young adults with cancer and their relatives. Conventional practice leaves referral and testing decisions to mostly non-expert clinicians implementing complex guidelines at the point of care, leading to substantial under-utilization. …

solid tumor
genetic testing
primary cancer
cancer diagnosis
  • 0 views
  • 20 Oct, 2021
  • 1 location
Recipient Site Pre-conditioning in Fat Grafting (me15Schaefer)

This study aims to investigate the preparation of the recipient site prior to autologous fat grafting (AFG) using different methods.

  • 15 views
  • 24 Mar, 2022
  • 2 locations