Found 46 clinical trials
Effects and Mechanisms of Ocrevus on Ambulatory Functions in People With Relapsing Multiple Sclerosis (MOBILE-RMS)
The purpose of this study is to test if people with relapsing multiple sclerosis (RMS) can improve ambulatory functions after one-year treatment with Ocrevus in comparison with other Disease
- 0 views
- 15 Oct, 2022
- 2 locations
Simulation-Free Hippocampal-Avoidance Whole Brain Radiotherapy Using Diagnostic MRI-Based and Cone Beam Computed Tomography-Guided On-Table Adaptive Planning in a Novel Ring Gantry Radiotherapy Device
radiation treatment positioning, etc.) while the patient is on the treatment table at fraction one using adaptive radiation planning. Adaptive radiotherapy is standard-of-care practice for other disease
- 0 views
- 23 Mar, 2022
- 1 location
Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery (TRICS-IV)
TRICS-IV is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in moderate to high risk patients who are 65 years of age or younger undergoing cardiac surgery on cardiopulmonary bypass, using a superiority trial design.
- 0 views
- 12 Mar, 2022
- 6 locations
An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEE (EPIK-OLE)
To assess the long-term safety and tolerability of XEN496 in pediatric subjects with KCNQ2 developmental and epileptic encephalopathy (KCNQ2-DEE) who had participated in the primary study (XPF-009-301).
- 0 views
- 07 Oct, 2022
- 12 locations
XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy (EPIK)
To investigate the potential antiseizure effects of adjunctive XEN496 (ezogabine) compared with placebo in children with KCNQ2 Developmental and Epileptic Encephalopathy (KCNQ2-DEE).
- 8 views
- 04 Oct, 2022
- 16 locations
Fibrinogen Replacement to Prevent Intracranial Haemorrhage in Ischemic Stroke Patients After Thrombolysis (FibER) (FibER)
Fibrinogen replacement could prevent haemorrhagic complications in ischemic stroke patients with secondary post-rtPA hypofibrinogenemia
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- 20 Apr, 2022
- 1 location
Genetic Testing in Young Adults With Cancer Study
The overarching goal of our research is to define an evidence-based, sustainable approach to identifying and managing genetic risk among young adults with cancer and their relatives. Conventional practice leaves referral and testing decisions to mostly non-expert clinicians implementing complex guidelines at the point of care, leading to substantial under-utilization. …
- 0 views
- 20 Oct, 2021
- 1 location
Impact of Cerebellar TMS on Brain and Cognitive Functions in Schizophrenia: a Pilot Study
This is a single-site, sham-controlled, randomized trial in a total of 60 subjects between ages 18 and 40 years with schizophrenia. This study will investigate the effects of 4-week rTMS treatment on brain and cognitive functions in patients. Subjects will be randomized to one of the following arms: Arm 1: …
- 0 views
- 04 Oct, 2022
- 1 location
Effects of Exercise in Patients With Metastatic Breast Cancer (EFFECT)
-Related Quality of Life (HRQoL), and other disease and treatment-related side effects at six months (primary endpoint).
- 0 views
- 09 Jul, 2022
- 1 location
Remote Ischemic Conditioning for the Treatment of Intracerebral Hemorrhage (RICH-2)
Intracerebral hemorrhage (ICH) results from the rupture of small vessels damaged by chronic hypertension, amyloid angiopathy or other disease. Currently, ICH has been a devastating type of
- 0 views
- 04 Oct, 2022
- 7 locations