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Found 263 clinical trials
Melatonin and Osteogenic Loading on Osteopenia (MelaOstrong)

This study will be assessing the efficacy of melatonin and/or osteogenic loading on modulating bone health in an osteopenic population.

dual-energy x-ray absorptiometry
melatonin
osteopenia
  • 10 views
  • 09 Apr, 2022
  • 2 locations
Bisphosphonates for Prevention of Post-Denosumab Bone Loss

idiopathic osteoporosis (IOP) enrolled in AAAN0161 (FD05114) "Denosumab for the prevention of post-teriparatide bone loss in premenopausal women with idiopathic osteoporosis". In addition, the

alendronate
denosumab
osteoporosis
forteo
zoledronic acid
  • 78 views
  • 03 Mar, 2022
Haemophilia and Bone Loss PHILEOS Study (PHILEOS)

clot formation, causing excessive bleeding (mainly haemarthrosis). Osteoporosis is a systemic bone disease characterized by a low bone mineral density (BMD). A decrease of mean BMD has been described

antihemophilic factor
deficiency
factor ix
osteoporosis
Accepts healthy volunteers
  • 15 views
  • 24 Oct, 2022
  • 19 locations
Denosumab to Prevent High-Turnover Bone Loss After Bariatric Surgery

Bariatric surgery leads to bone loss and increases fracture risk. This study evaluates whether denosumab can prevent the high-turnover bone loss that occurs after Roux-en-Y Gastric Bypass (RYGB

zoledronic acid
denosumab
gastrectomy
gastric bypass
roux-en-y
  • 1 views
  • 27 Apr, 2022
  • 1 location
Marginal Bone Loss in Single Implant Restaurations With Different Methods

The investigator is going to measure the marginal bone loss in single implant restaurations with three different methods: direct overcast, milled cad/cam direct to implant restauration and

Accepts healthy volunteers
  • 0 views
  • 27 Apr, 2022
  • 1 location
Zoledronic Acid for Prevention of Bone Loss After BAriatric Surgery (ZABAS) (ZABAS)

In a randomised placebo-controlled trial assess effects of zoledronic acid for prevention of bone and muscle loss after bariatric surgery.

zoledronic acid
  • 0 views
  • 01 Jul, 2022
  • 1 location
Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Women - A Randomised Controlled Trial (BoneZone)

The Bone Zone trial is a prospective, multi-centre, double-blind, phase II, randomised controlled trial evaluating the effect of denosumab or zoledronic acid compared to placebo on change in bone mineral density over one year in women aged 50 years or older requiring admission to intensive care for greater than 24 …

bone mineral density
zoledronic acid
denosumab
  • 0 views
  • 17 Oct, 2022
  • 10 locations
Evaluation and Management of Metabolic Bone Disease in Kidney Transplant Recipients

There is a well-documented increased risk for disordered mineral bone homeostasis in Kidney Transplant Recipients (KTRs) when compared to the general population, leading to a markedly increased risk for fragility fractures and their associated morbidity and mortality. A more uniform and rigorous evaluation of bone and mineral homeostasis,than is afforded …

metabolic bone disease
kidney transplant
Accepts healthy volunteers
  • 1 views
  • 08 Feb, 2022
  • 1 location
Open Versus Arthroscopic Stabilization of Shoulder Instability With Subcritical Bone Loss: The OASIS Trial (OASIS)

patient-reported physical function for military personnel and civilians with traumatic anterior shoulder instability and 10-20% glenoid bone loss.

  • 0 views
  • 07 Oct, 2022
  • 2 locations
Food Trial Evaluating the Efficacy of SBD111 Versus Placebo for the Clinical Dietary Management of the Metabolic Processes of Osteopenia

The aim of the trial is to determine if the SYNBIOTIC (prebiotic and probiotic), provided twice daily (capsule) will help support skeletal health in otherwise healthy postmenopausal women in the early years postmenopause (1-6 years post last menstruation) over a 12-month period.

calcium
Accepts healthy volunteers
osteopenia
bone mineral density
body mass index
  • 0 views
  • 24 Mar, 2022
  • 1 location