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Found 44 clinical trials
Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension

Patients with autonomic failure are characterized by disabling orthostatic hypotension (low blood pressure on standing), and at least half of them also have high blood pressure while lying down

parkinson's disease
multiple system atrophy
orthostatic hypotension
hypertension
pure autonomic failure
  • 174 views
  • 25 Mar, 2022
  • 1 location
Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury (HemON)

-acute or chronic spinal cord injury (>= 1 month post injury) between C3 and T6 inclusive, who suffer from orthostatic hypotension.

electrical stimulation
spinal cord
spinal cord disorder
  • 0 views
  • 24 Oct, 2022
  • 1 location
Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic

orthostatic hypotension
hypertension
cpap
  • 3 views
  • 04 Oct, 2022
  • 1 location
Spinal Cord Stimulation for Multiple System Atrophy

evaluate the improvement of dysarthria, dysphagia, urinary retention and orthostatic hypotension in multiple system atrophy (MSA) patients before and after SCS treatment, and shed new light on the

orthostatic hypotension
  • 0 views
  • 23 Mar, 2022
  • 1 location
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury (STIMO HEMO)

Stimulation (TESS) to ensure the long-term management of hemodynamic instability and reduce the incidence and severity of orthostatic hypotension and autonomic dysreflexia episodes in humans with chronic

spasticity
autonomic dysreflexia
spinal cord injury thoracic
spinal cord disorder
spinal cord
  • 0 views
  • 07 Jun, 2022
  • 1 location
n-3 Polyunsaturated Fatty Acids to Prevent and Treat Diabetic Neuropathy (NMF)

. CAN often goes unrecognized because it presents with non-specific symptoms, such as resting tachycardia and fixed heart rate, exercise intolerance, and orthostatic hypotension. However, CAN is a

foot ulceration
diabetic neuropathy
diabetes
autonomic neuropathy
  • 0 views
  • 29 Jun, 2022
  • 2 locations
Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure

Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is effective …

hypertension
  • 6 views
  • 04 Oct, 2022
  • 1 location
NORTHERA (DROXIDOPA) for Dysautonomia in Adult Survivors of Menkes Disease and Occipital Horn Syndrome

The purpose of this study is to evaluate whether Northera (Droxidopa) is safe and effective in young adults with Menkes disease who survived the most severe complications of their illness or adults with occipital horn syndrome (OHS), who have trouble with intermittent low blood pressure and other symptoms of dysautonomia. …

  • 2 views
  • 01 Aug, 2021
  • 1 location
Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease (Protocol 53136)

REM Behavior Sleep Disorder (RBD) is a sleep disorder causing people to 'act out' their dreams. A high percentage of individuals with idiopathic RBD (iRBD) are known to develop conditions affecting the neurons in the brain such as Parkinson's disease (PD). Based on the increased risk to develop PD, individuals …

parkinson's disease
antidepressants
dyschromatopsia
loss of smell
constipation
  • 64 views
  • 07 Oct, 2022
  • 1 location
Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17

This is a phase II study using risk and response-adapted therapy for low, intermediate and high risk classical Hodgkin lymphoma. Chemotherapy regimens will be based on risk group assignment. Low-risk and intermediate- risk patients will be treated with bendamustine, etoposide, Adriamycin® (doxorubicin), bleomycin, Oncovin® (vincristine), vinblastine, and prednisone (BEABOVP) chemotherapy. …

chemotherapy regimen
classical hodgkin lymphoma
brentuximab
vinblastine
bendamustine
  • 12 views
  • 04 Oct, 2022
  • 6 locations