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Found 44 clinical trials
Abdominal Binders to Treat Orthostatic Hypotension in Parkinsonian Syndromes (ABOH-PS)

The purpose of the present clinical trial is to determine whether the use of an elastic abdominal binder is effective in the non-pharmacological management of symptomatic, neurogenic orthostatic

movement disorder
orthostatic hypotension
  • 0 views
  • 25 Jan, 2022
  • 1 location
Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms

The objective of this study is to find a more objective and accurate way to assess the efficacy of the treatment for neurogenic orthostatic hypotension. For this purpose, the investigators will

parkinson's disease
midodrine
systolic blood pressure
orthostatic hypotension
pure autonomic failure
  • 50 views
  • 25 Jan, 2022
  • 1 location
Effect of Levodopa on Cardiovascular Autonomic Function in Parkinson's Disease

in PD is poorly understood. Orthostatic hypotension has been documented as a potential side effect of levodopa. As a result, clinicians may be reluctant to prescribe levodopa in patients with PD with

parkinson's disease
systolic blood pressure
dopamine
motor symptoms
levodopa
  • 0 views
  • 04 Oct, 2022
  • 1 location
Blood Pressure Effects on Cognition and Brain Blood Flow in PD

thinking and orthostatic hypotension (OH), i.e., low blood pressure (BP) when standing. About one-third of people with PD have OH, which can cause sudden, temporary symptoms while upright, including

parkinson's disease
light-headedness
motor symptoms
dizziness
orthostatic hypotension
  • 1 views
  • 04 Oct, 2022
  • 1 location
Effects of Blueberries in Older Adults (BnD)

This randomized, parallel-design trial will evaluate specific clinical and physiological effects of whole blueberries in adults 70 years of age or older at a congregate-living facility.

Accepts healthy volunteers
  • 0 views
  • 11 Jul, 2022
  • 1 location
Deciphering Preserved Autonomic Function After Spinal Cord Injury

This study looks to characterize gradients of dysfunction in the autonomic nervous system after spinal cord injury. The autonomic nervous system plays key roles in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals with spinal cord injury typically suffer. Focusing on blood pressure regulation, …

autonomic dysreflexia
Accepts healthy volunteers
spinal cord disorder
neurologic findings
nervous
  • 0 views
  • 07 Jul, 2022
  • 1 location
Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

The purpose of this study is to learn more about the effects of midodrine and droxidopa, two medications used for the treatment of orthostatic hypotension (low blood pressure on standing), on

parkinson's disease
midodrine
systolic blood pressure
droxidopa
atrophy
  • 277 views
  • 16 Jun, 2022
  • 1 location
Transcutaneous Spinal Neuromodulation to Normalize Autonomic Phenotypes

This study looks to characterize autonomic nervous system dysfunction after spinal cord injury and identify the potential role that transcutaneous spinal cord stimulation may play at altering neuroregulation. The autonomic nervous system plays key parts in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals …

autonomic dysreflexia
Accepts healthy volunteers
spinal cord disorder
neurologic findings
nervous
  • 0 views
  • 28 Oct, 2022
  • 1 location
Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

The purpose of this study is to learn more about the effects of abdominal compression and the medication midodrine, two interventions used for the treatment of orthostatic hypotension (low blood

systolic blood pressure
orthostatic hypotension
midodrine
pure autonomic failure
  • 0 views
  • 19 Jun, 2022
  • 1 location
CPAP for the Treatment of Supine Hypertension

This study aims to learn about the effects of continuous positive airway pressure (CPAP) on people with autonomic failure and high blood pressure when lying down (supine hypertension) to determine if it can be used to treat their high blood pressure during the night. CPAP (a widely used treatment for …

hypertension
systolic blood pressure
orthostatic hypotension
pure autonomic failure
  • 0 views
  • 04 Oct, 2022
  • 1 location