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Found 95 clinical trials
Phase I/II Trial of HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PD-L1/TGF-Beta Trap (M7824) in Subjects With HPV Positive Cancers

metastatic HPV associated cancer (Phase I) or stage II or III p16-positive oropharyngeal cancer (Phase II) Design Participants will be screened with: Medical

oropharyngeal carcinoma
atezolizumab
solid tumors
chemoradiotherapy
oropharyngeal cancer
  • 7 views
  • 27 Oct, 2022
  • 1 location
  • 0 views
  • 30 May, 2022
  • 1 location
Radiotherapy vs. Trans-Oral Surgery for HPV-Negative Oropharyngeal Squamous Cell Carcinoma

The goal of this randomized phase II study is a formal comparison of radiotherapy versus trans-oral surgery as the primary treatment of HPV-negative patients with early-stage oropharyngeal

primary tumor
neck dissection
oropharyngeal carcinoma
oropharyngeal
squamous cell carcinoma
  • 32 views
  • 25 Jan, 2021
  • 1 location
Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis

As mentioned above, several prior studies have shown the positive effects of oral use of aloe vera juice in managing chemotherapy and radiation-induced oral mucositis and esophagitis. This study aims to add to the existing body of research around aloe vera juice and its effects on oral mucositis and esophagitis. …

mucositis
  • 0 views
  • 26 May, 2022
  • 1 location
Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer

The purpose of this study is to compare any good or bad effects of using pembrolizumab (an experimental drug) and radiation therapy (RT), compared to using cisplatin chemotherapy and radiation therapy (RT) in the treatment of patients with head and neck squamous cell carcinoma (HNSCC).

chemoradiotherapy
caries
primary cancer
carcinoma
carcinoma of oropharynx
  • 1 views
  • 04 Mar, 2022
  • 7 locations
Autologous Muscle Derived Cells for Gastro-Intestinal Repair (AMDC-GIR) for Tongue Dysphagia

dysphagia in male and female patients who have undergone surgery and/or chemo- and/or radiotherapy for squamous cell cancer of the oropharynx.

  • 0 views
  • 04 Oct, 2022
  • 1 location
  • 0 views
  • 20 Apr, 2022
  • 1 location
Autologous Muscle Derived Cells for Treatment of Tongue Dysphagia

treatments of tongue dysphagia in male and female patients who have undergone surgery and/or chemo- and/or radiotherapy for squamous cell cancer of the oropharynx.

  • 0 views
  • 28 Jun, 2022
  • 1 location
Hypofractionated Proton Therapy for the Treatment of Head and Neck Cancer, The HEADLIGHT Study"

This clinical trial tests whether intensity modulated proton therapy after surgery works to shrink tumors in patients with head and neck cancer. Radiation therapy uses high energy protons to kill tumor cells and shrink tumors.

  • 0 views
  • 20 Apr, 2022
  • 2 locations
Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment

This clinical trial evaluates the tolerability of a physical activity program in head and neck cancer patients who are undergoing cancer treatment. The goal of this trial is to give patients exercises prescribed by a physical therapist that they are able to complete regularly at home. Increasing physical activity may …

cancer
  • 0 views
  • 16 Jun, 2021
  • 1 location