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Found 95 clinical trials
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer. (NECTORS)

The objective of this trial is to study the efficacy of treatment of human papilloma virus (HPV) related oropharyngeal cancer with chemotherapy followed by Transoral Robotic Surgery (TORS) as

carcinoma
robotic surgery
cancer
primary tumor
papilloma
  • 0 views
  • 28 Apr, 2022
  • 1 location
Investigating the Association Between Microbiota and Esophageal/Oropharyngeal Cancer

whether oral microbiota can be a non-invasive biomarker of oropharyngeal cancer, esophageal cancer, synchronous cancer and chemoradiation resistance. And whether probiotic supplement can improve oral

Accepts healthy volunteers
carcinoma of oropharynx
oropharyngeal
esophagus cancer
  • 0 views
  • 13 Jun, 2022
  • 1 location
Stereotactic Boost and Short-course Radiation Therapy for Oropharynx Cancer (SHORT-OPC)

neck in human papilloma associated oropharynx cancer vs. the current standard 7-week course chemoradiation.

carcinoma
chemoradiotherapy
cancer
primary tumor
papilloma
  • 55 views
  • 10 May, 2022
  • 1 location
Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer

This prospective study aims to utilize pre- and mid-treatment PET-CT to guide de-escalation of radiation therapy in HPV-related squamous cell carcinoma of the oropharynx.

carcinoma
cancer
avid
immunohistochemistry
oropharyngeal squamous cell carcinoma
  • 9 views
  • 24 Mar, 2022
  • 2 locations
Anti-EGFR Therapy With IMRT Concurrent Chemoradiotherapy in Locally Advanced OPC Resistant to Induction Chemotherapy

advanced oropharyngeal carcinoma (OPC) with induced chemotherapy resistance. Eligibility criteria include histologically confirmed locally advanced OPC according to the American Joint Committee on

EGFR
monoclonal antibodies
chemoradiotherapy
cancer
induction chemotherapy
  • 0 views
  • 26 Apr, 2022
  • 1 location
Assessment of Swallowing Function and Quality of Life in Oropharyngeal Cancer Patients Treated by Chemo-radiotherapy

Open-label, interventional, multicentric, randomized, phase III study. Cancer studied is the oropharyngeal cancer. Study is composed by 2 arms of subjects: prophylactic or reactive

carcinoma
cancer
squamous cell carcinoma of the head and neck
renal function test
neutrophil count
  • 0 views
  • 24 Jan, 2021
  • 2 locations
Phase II Trial of Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer

This is a trial studying patients with human papilloma virus (HPV) positive oropharyngeal cancer with tumors that can be removed via transoral surgery. Following surgery, patients will be

  • 0 views
  • 23 Oct, 2022
  • 1 location
Use of a Proliferation Saturation Index to Determine Personalized Radiotherapy for HPV + Oropharyngeal Cancers

This study is to determine whether a mathematical model can be used to choose a radiation delivery method to improve the rate of a rapid response.

carcinoma
squamous cell carcinoma
metastasis
cancer
measurable disease
  • 4 views
  • 07 Oct, 2022
  • 1 location
Radiotherapy Dose De-escalation in HPV-Associated Cancers of the Oropharynx

The purpose of this study is to use intra-treatment 18FDG-PET/CT during definitive radiation therapy for human papillomavirus (HPV)-related oropharyngeal cancer (OPC) as an imaging biomarker to

  • 0 views
  • 04 Oct, 2022
  • 2 locations
HYHOPE: De-intensified Hypofractionated Radiation Therapy for HPV-associated Oropharynx Cancer

This is a single arm Phase I study of de-intensified hypofractionated radiation therapy for favorable human papilloma virus-associated oropharynx cancer. It will evaluate the tolerability of a

  • 0 views
  • 22 Mar, 2022
  • 1 location