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Found 105 clinical trials
Ultrasound Characterization of Ovarian Follicle Dynamics During Weight Loss

The objective of this study is to explore the effects of weight loss on body composition, metabolic status, reproductive hormones, and ovarian follicle development in obese women with regular menstrual cycles versus obese women with irregular menstrual cycles and/or polycystic ovary syndrome (PCOS).

multivitamins
polycystic ovary syndrome
insulin
Accepts healthy volunteers
hormonal contraception
  • 284 views
  • 16 Oct, 2022
  • 1 location
Cardiometabolic Effects of Sweet Cherry Juice

This study aims to determine the effects of consuming sweet cherry juice on cardiovascular function, glucose regulation, and lipid status in overweight human subjects. The investigators hypothesize that sweet cherry juice consumption will improve metabolic and physiological status in overweight persons compared to a placebo.

Accepts healthy volunteers
body mass index
blood pressure diastolic
systolic blood pressure
  • 33 views
  • 13 Mar, 2022
  • 1 location
Application of Time Restriction Feeding in Patients With Type 2 Diabetes Mellitus

In this 3-week interventional study, the investigators hypothesize that therapeutic Time-Restricted Feeding in patients with poorly controlled Type 2 diabetes mellitus (T2DM) can improve their mean glucose or estimated glycated hemoglobin levels with the same dose, or even reduced dose, of antidiabetics.

antidiabetic agents
fasting
type 2 diabetes mellitus
  • 0 views
  • 22 Mar, 2022
  • 1 location
Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age (SHK002)

The goal of this study is to determine the relative desirability of metformin vs. oral combined hormonal contraceptives (OCs) in treating Polycystic Ovary Syndrome (PCOS) in women of later reproductive age. Polycystic Ovary Syndrome Questionnaire (PCOSQ) score will be used as a proxy for patient satisfaction. In light of their …

insulin
estradiol
Accepts healthy volunteers
type 2 diabetes mellitus
impaired glucose tolerance
  • 197 views
  • 15 Feb, 2022
  • 1 location
Liraglutide in the Prevention of Type 2 Diabetes After Gestational Diabetes (Liragest)

Obese women with history of gestational diabetes are in great danger to develop type 2 diabetes (T2D) within 5-10 years after delivery. Aim of the study is to investigate if 12 months' liraglutide treatment could decrease the risk of T2D in obese women who have had gestational diabetes. The women …

diabetes
insulin
liraglutide
metformin
Accepts healthy volunteers
  • 1 views
  • 23 May, 2022
  • 1 location
Acupuncture or Metformin for Insulin Resistance in Women With PCOS (PIAII)

The hypothesis is that acupuncture is equally effective as metformin (both treatments combined with lifestyle management) in improving whole body glucose homeostasis in insulin resistant women with polycystic ovary syndrome (PCOS), and that both are superior to lifestyle management alone. The investigators hypothesize that acupuncture and metformin induce ovulation and …

insulin
transvaginal ultrasound
insulin resistance
cushing's syndrome
Accepts healthy volunteers
  • 717 views
  • 02 Jul, 2022
  • 2 locations
Investigation of Cinnamon Spice on Glucose Tolerance in Subjects With Pre-diabetes (CINNII)

This study aims to determine whether the effectiveness of cinnamon spice capsules vs. placebo capsules on glucose tolerance in prediabetic subjects who are overweight or obese.

hemoglobin a1c
polyphenol
diabetes
glycosylated hemoglobin
prediabetic state
  • 77 views
  • 04 Mar, 2022
  • 1 location
Comparative Analysis Between Sleeve Gastrectomy and Roux-en Y Gastric Bypass in Bariatric Operation

Prospective, double-arm, multi-center cohort study on obese patients, for laparoscopic sleeve gastrectomy versus Roux-en Y gastric bypass

  • 0 views
  • 26 Jan, 2021
  • 1 location
Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS)

This study aims to test the following hypotheses in a randomized controlled trial of post-partum women with a history of gestational diabetes mellitus (GDM) that will be followed up for up to 4 years: Post-partum pregnancy is ideal for behavioural modification and adopting a healthy lifestyle. Using the continous glucose …

hemoglobin a1c
diabetes
fasting
flash
oral glucose tolerance test
  • 0 views
  • 25 Oct, 2021
  • 1 location
Light and the Effect on Metabolic Syndrome and Alzheimer's Disease

This study's main hypothesis is that a delivering a tailored lighting intervention (TLI) will provide a successful means for promoting circadian entrainment and treating metabolic disease and inflammation in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) and Alzheimer's disease and related dementias (ADRD). As such, the proposed …

dementia
metabolic syndrome
alzheimer's disease
depression
cognitive impairment
  • 12 views
  • 12 May, 2022
  • 3 locations