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Found 105 clinical trials
Effects of Inositol Alone or Associated With Alpha-lipoic Acid in Polycystic Ovary Syndrome Treatment

levels, SHBG levels) metabolic profile: glycemia and insulinemia at fasting and after oral glucose tolerance test (OGTT), serum lipids insulin-sensitivity measured by the

insulin
testosterone
progesterone
fasting
inositol
  • 42 views
  • 02 Jun, 2021
  • 1 location
Effect of Serum LDL Cholesterol Concentration on Pancreatic Insulin Secretion

weeks in patients with medical indication for a treatment with a PCSK9-inhibitor. Therefore, patients will either undergo a hyperglycemic clamp or a oral glucose tolerance test in randomized manner.

low density lipoprotein
evolocumab
cardiovascular disease
type 2 diabetes mellitus
dyslipidemia
  • 84 views
  • 07 Oct, 2022
  • 1 location
Transport of Satiety Factors Into the CSF

case on the same day. Simultaneous samplings of blood and CSF are taken from 10 patients after an oral glucose tolerance test. These interventions are carried out to investigate in which extent

insulin
glucagon-like peptide 1
glucagon-like peptide-1
glucagon
fasting
  • 0 views
  • 10 Apr, 2022
  • 1 location
Compassionate Use of Metreleptin in Previously-Treated Patients With Generalized Lipodystrophy

daily injections. They will have: plastic catheter placed in an arm vein. blood tests, urine collection, and physical exam. oral glucose tolerance test, drinking a

insulin
x-rays
sweet
oral glucose tolerance test
glucose tolerance test
  • 14 views
  • 16 Oct, 2022
  • 1 location
Phase II Trial of Liraglutide (Saxenda(R), Novo Nordisk) in Adolescents With Obesity After Sleeve Gastrectomy: A Pilot Open-Label Study

will measure their physical activity. Some screening tests will be repeated during the study. Participants will have an oral glucose tolerance test. They will ingest a sweet liquid. Blood

liraglutide
sleeve gastrectomy
fats
oral glucose tolerance test
bariatric surgery
  • 46 views
  • 17 Oct, 2022
  • 1 location
COLSIO Trial: Phase II Randomized, Controlled Trial of Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity

Glucose Tolerance Test (OGTT). For this, they will drink a sweet liquid and then give blood samples. They will get a 12-week supply of the study drug or placebo to take daily by mouth.

insulin
body mass index
sugars
cardiovascular disease
fasting
  • 4 views
  • 13 Oct, 2022
  • 1 location
Healthy Eating in Women at Risk of Gestational Diabetes (SAGE)

Healthy eating during pregnancy has favorable effects on markers related to diabetes (glucose tolerance) and is associated with lower gestational diabetes mellitus (GDM) risk. The cornerstone of GDM treatment is nutrition therapy but the latter often starts late in pregnancy and thus may not have the expected effects on glucose …

diabetes
pcos
Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Biomarkers of Increased Free Living Sleep Time

This protocol will increase sleep duration in participants who maintain less than 6 hours sleep per night, to target the recommended 7 hours of sleep per night. The focus of this study is determine how increasing nightly sleep duration in these individuals who maintain less than 6 hours sleep per …

insulin
body mass index
hypersomnia
  • 25 views
  • 10 Jul, 2021
  • 2 locations
Phenotyping Genetic Risk for Type 2 Diabetes

This study tests the hypothesis that non-diabetic individuals with a high genetic risk score for type 2 diabetes have impaired glucose tolerance and insulin resistance compared to those with a low genetic risk score for type 2 diabetes.

impaired glucose tolerance
Accepts healthy volunteers
insulin resistance
  • 12 views
  • 22 Mar, 2022
  • 1 location
Effect of Whole Fruit on Glycemic Control in Adults With Type 2 Diabetes

Diabetes costs the U.S. healthcare system more than any other disease, and nearly half of Americans will develop either diabetes or prediabetes in their lifetime. It is therefore critical to find new strategies to treat or reverse diabetes. One such approach is adopting a healthy diet, which can dramatically improve …

  • 0 views
  • 11 Dec, 2021
  • 1 location