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Found 83 clinical trials
Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer

The purpose of this study is to compare any good or bad effects of using pembrolizumab (an experimental drug) and radiation therapy (RT), compared to using cisplatin chemotherapy and radiation therapy (RT) in the treatment of patients with head and neck squamous cell carcinoma (HNSCC).

carcinoma of oropharynx
chemoradiotherapy
cancer
pembrolizumab
carcinoma
  • 0 views
  • 13 Oct, 2021
  • 7 locations
9-ING-41 Plus Carboplatin in Salivary Gland Carcinoma

This trial is investigating an intravenous (IV) medication called 9-ING-41 in combination with chemotherapy (carboplatin) for the treatment of advanced salivary gland cancers. The names of the study drug(s) involved in this study are: 9-ING-41 (a GSK-3 inhibitor) Carboplatin chemotherapy

cancer
biological factors
carcinoma
neutrophil count
monoclonal antibodies
  • 0 views
  • 27 Oct, 2021
  • 2 locations
Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer

This study will examine the combination of pembrolizumab and tadalafil for safety and efficacy in advanced head and neck cancer.

metastatic squamous cell carcinoma
tadalafil
measurable disease
head and neck cancer
advanced head and neck carcinoma
  • 0 views
  • 02 Jul, 2021
  • 1 location
Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous Mucosal or Superficial Soft Tissue Neoplasia.

A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for superficial cutaneous, mucosal or soft tissue neoplasia

cancer
platelet count
cavity
cancer treatment
measurable disease
  • 0 views
  • 30 Jan, 2021
  • 1 location
Alpha Radiation Emitters Device for the Treatment of Cutaneous Mucosal or Superficial Soft Tissue Neoplasia (DaRT)

A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for superficial cutaneous, mucosal or soft tissue neoplasia

cancer
platelet count
cavity
cancer treatment
  • 0 views
  • 25 Mar, 2021
  • 1 location
Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous Mucosal or Superficial Soft Tissue Neoplasia

A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for superficial cutaneous, mucosal or soft tissue neoplasia

  • 0 views
  • 30 Jan, 2021
  • 1 location
Retreatment With Intratumoral Diffusing Alpha Radiation Emitters

A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for superficial cutaneous, mucosal or soft tissue neoplasia

  • 0 views
  • 03 Feb, 2021
  • 1 location
Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment

This clinical trial evaluates the tolerability of a physical activity program in head and neck cancer patients who are undergoing cancer treatment. The goal of this trial is to give patients exercises prescribed by a physical therapist that they are able to complete regularly at home. Increasing physical activity may …

cancer
  • 0 views
  • 16 Jun, 2021
  • 1 location
Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST Advanced HER2 Positive Solid Tumors

This study is a first in human Phase 1 study that involves patients with a type of cancer called HER2 (Human Epidermal Growth Factor Receptor 2) positive cancer. This study asks patients to volunteer to take part in a research study investigating the safety and efficacy of using special immune …

human epidermal growth factor
total bilirubin
renal function
lung carcinoma
absolute neutrophil count
  • 0 views
  • 01 Aug, 2021
  • 1 location
Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin

This phase I trial investigates the side effects and best dose of peposertib when given together with radiation therapy in treating patients with head and neck cancer that has spread to other places in the body (advanced) who cannot take cisplatin. Peposertib may stop the growth of tumor cells by …

  • 0 views
  • 09 Jan, 2022
  • 9 locations