Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 83 clinical trials
Prevention of Oral DNA Damage by Black Raspberries

The purpose of this voluntary research study is to learn about the potential effects that black raspberry (BRB) lozenges may have on reducing the damage caused from cigarette smoke in mouth cells in adult smokers, which may be useful in reducing health risks associated with smoking.

Accepts healthy volunteers
  • 0 views
  • 07 Dec, 2021
  • 1 location
LLL Phototherapy in Oral Lesions Resulting From Anti-neoplastic Prevention

Introduction: There are several manifestations in the oral mucosa resulting from antineoplastic treatments by chemo (QT) or radiotherapy (RT). In this study we will collect the variables referring to oral mucositis (OM), radiodermatitis, osteonecrosis of the jaws (ONJ), hyposalivation and xerostomia, dysgeusia, pain, oral candidiasis (opportunistic infection), trismus, quality of …

antineoplastic
mucositis
  • 0 views
  • 05 Aug, 2021
  • 1 location
Pembrolizumab With Chemotherapy for Poorly Chemo-responsive Thyroid and Salivary Gland Tumors

Phase II, 2-cohort, single arm trial treated with the combination of the following two agents Pembrolizumab (MK3475) 200mg, every three weeks, iv Docetaxel 75mg/m2, every three weeks, iv

neutrophil count
docetaxel
adenocarcinoma
angiogenesis inhibitor
carcinoma
  • 119 views
  • 24 Nov, 2021
  • 1 location
A New Membrane Obturator Prothesis Concept for Soft Palate Defects

When soft palate defects lead to palatal insufficiency, the patient's quality of life is affected by difficulties swallowing, hypernasality, and poor intelligibility of speech. If immediate surgical reconstruction is not an option, the patient may benefit from the placement of a rigid obturator prosthesis. Unfortunately, the residual muscle stumps are …

obturator prosthesis
stiff
  • 0 views
  • 16 Sep, 2021
  • 2 locations
9-ING-41 Plus Carboplatin in Patients With Advanced Metastatic Salivary Gland Carcinoma

9-ING-41 is a small molecule potent selective GSK-3 inhibitor with antitumor activity. This study investigates 9-ING-41 in combination with carboplatin chemotherapy in patients with incurable, recurrent or metastatic salivary gland carcinomas (SGC). Patients with advanced SGC (including all histologic subtypes and adenoid cystic carcinoma [ACC]) will receive 9-ING-41 intravenously (IV) …

cancer
neutrophil count
carboplatin
  • 0 views
  • 08 Oct, 2021
  • 1 location
Customized 3D Printed Oral Stents During Head and Neck Radiotherapy

This clinical trial studies the effect of customized 3 dimensional (3D) printed oral tents on patients with head and neck cancer who are receiving radiotherapy. Oral stents are made from the impression of patients' mouth and cover patients' teeth and gums during radiation therapy. A customized, 3D-printed oral stent may …

  • 0 views
  • 08 Nov, 2021
  • 4 locations
Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

This is a prospective, multi-center, open-label, non-randomized, multi-arm phase II trial to evaluate the efficacy of combination therapy with pembrolizumab and cetuximab for patients with recurrent/metastatic HNSCC. There will be four patient cohorts, including a PD-1/PD-L1 inhibitor-nave, cetuximab-nave arm (Cohort 1), a PD-1/PD-L1 inhibitor-refractory, cetuximab-nave arm (Cohort 2), a PD-1/PD-L1 …

squamous cell carcinoma of the head and neck
pd-l1
mk-3475
renal function test
carcinoma
  • 509 views
  • 21 Mar, 2021
  • 4 locations
STEREO-POSTOP 01 (PostOperative Hypofractionated Stereotactic Body Radiotherapy ) - GORTEC 2017-03

treatment of early stage oropharyngeal and oral cavity cancer with high risk margins.

neck dissection
oral cavity cancer
carcinoma
squamous cell carcinoma of the oral cavity
dental caries
  • 4 views
  • 08 Aug, 2021
  • 24 locations
Cell-free Tumor DNA in Head and Neck Cancer Patients

This study investigates if head and neck squamous cell carcinoma can be tracked with cell-free tumor DNA, RNA or HPV-DNA, in blood samples from patients referred with suspicion of cancer, and if it can be used in detecting recurrence in patients already diagnosed and treated for head and neck squamous …

head and neck cancer
squamous cell carcinoma of head and neck
cancer
squamous cell carcinoma
neck cancer
  • 0 views
  • 26 Sep, 2021
  • 1 location
Alpha Radiation Emitters Device for the Treatment of Cutaneous Mucosal and Superficial Soft Tissue Neoplasia (DaRT)

A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for superficial cutaneous, mucosal or soft tissue neoplasia

cancer
cancer treatment
  • 0 views
  • 27 Jul, 2021
  • 1 location