Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 85 clinical trials
APG-115 in Salivary Gland Cancer Trial

This is a phase I/II trial to evaluate the efficacy of APG-115 +/- Carboplatin for the treatment p53 wild-type malignant salivary gland cancer. Part 1 consisted of 2 arms, arm A (APG-115 monotherapy) and arm B (APG-115 + Carboplatin) and was terminated early. Part 2 is a single arm study …

  • 0 views
  • 21 Mar, 2022
  • 2 locations
Cyclin D1 Based TPF Induction Chemotherapy for Oral Squamous Cell Carcinoma Patients at Clinical N2 Stage

The purpose of this study is to To confirm the predictive value of CCND1 for TPF induction in cN2 patients with OSCC

platelet count
chemotherapy regimen
cavities
renal function
carcinoma
  • 19 views
  • 24 Feb, 2022
  • 1 location
GDF15 Based TPF Induction Chemotherapy for OSCC Patients

The purpose of this study is to confirm the predictive value of GDF15 expression for TPF induction in T3/T4cN0M0 patients with OSCC

neck dissection
platelet count
chemotherapy regimen
cavities
renal function
  • 18 views
  • 25 Feb, 2022
  • 1 location
A Phase II Trial of TPF Induction Chemotherapy in cN2 OSCC Patients

To confirm the subgroup result from TPF (docetaxel, cisplatin and 5-fluorouracil ) trial (NCT01542931) that cN2 OSCC patients could benefit from TPF induction chemotherapy compared to the standard treatment.

neck dissection
platelet count
chemotherapy regimen
cavities
renal function
  • 0 views
  • 07 Oct, 2021
  • 1 location
Lenvatinib and Pembrolizumab in People With Advanced Adenoid Cystic Carcinoma and Other Salivary Gland Cancers

The purpose of this study is to see if the study drugs, lenvatinib and pembrolizumab, are effective in treating advanced Adenoid Cystic Carcinoma (ACC) or other salivary gland cancers that have come back and/or spread to other parts of the body. Researchers are also doing this study to test the …

pet scan
anticoagulants
ct scan
pembrolizumab
cancer
  • 6 views
  • 10 Jul, 2022
  • 8 locations
Improved Implant for Reconstruction Purposes After Mandibular Resection (RifRam)

Study design: A single center non-randomized, prospective clinical feasibility study. Study population: Study population is composed of 10 patients ineligible for a free-flap bone reconstruction. Intervention: The selected patients will receive the newly developed, patient-specific RIfRaM mandibular implant. Objective: The aim is to provide enough evidence through model analysis, physical …

Accepts healthy volunteers
  • 0 views
  • 24 Mar, 2022
  • 1 location
Evaluation of the Photobiomodulation Using LED Lamp for Curative Treatment of Radio-induced Mucositis.

This is a monocentric, prospective, non-comparative phase II study with minimal risks and constraints. The study will aim to assess the curative treatment of radio-induced mucositis by photobiomodulation using LED lamp.

squamous cell carcinoma
mucositis
carcinoma
  • 0 views
  • 29 Oct, 2021
  • 1 location
Lutetium-177-PSMA Radioligand Therapy in Advanced Salivary Gland Cancer Patients

Phase 2 pilot study, which evaluates the safety and efficacy of Lutetium-177-PSMA radioligand therapy in advanced salivary gland cancer patients.

pet scan
ct scan
neutrophil count
cancer
measurable disease
  • 0 views
  • 06 Oct, 2021
  • 1 location
Prevention of Oral DNA Damage by Black Raspberries

The purpose of this voluntary research study is to learn about the potential effects that black raspberry (BRB) lozenges may have on reducing the damage caused from cigarette smoke in mouth cells in adult smokers, which may be useful in reducing health risks associated with smoking.

Accepts healthy volunteers
  • 0 views
  • 07 Dec, 2021
  • 1 location
LLL Phototherapy in Oral Lesions Resulting From Anti-neoplastic Prevention

Introduction: There are several manifestations in the oral mucosa resulting from antineoplastic treatments by chemo (QT) or radiotherapy (RT). In this study we will collect the variables referring to oral mucositis (OM), radiodermatitis, osteonecrosis of the jaws (ONJ), hyposalivation and xerostomia, dysgeusia, pain, oral candidiasis (opportunistic infection), trismus, quality of …

mucositis
antineoplastic
  • 0 views
  • 22 Mar, 2022
  • 1 location