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Found 93 clinical trials
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Correlation of FAZA PET Hypoxia Imaging To 3D Histology in Oral Tongue Cancer

This is a pilot study in the form of a prospective Phase II, single centre, single arm hypoxia study of oral tongue cancer with FAZA-PET imaging and pimonidazole targeted IHC of surgical specimens.

squamous cell carcinoma
international normalized ratio
hypoxia
platelet count
carcinoma
  • 39 views
  • 28 Oct, 2021
  • 1 location
None
Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

This research is being done to see how safe and effective the use of the study drug Ado-trastuzumab (T) emtansine (DM1), T-DM1, and standard of care chemoradiation are when used together in treating HER2-positive salivary gland cancer. It will also examine the effectiveness of study drug Ado-trastuzumab (T) emtansine (DM1) …

  • 1 views
  • 09 Jan, 2022
  • 2 locations
None
Lenvatinib and Pembrolizumab in People With Advanced Adenoid Cystic Carcinoma and Other Salivary Gland Cancers

The purpose of this study is to see if the study drugs, lenvatinib and pembrolizumab, are effective in treating advanced Adenoid Cystic Carcinoma (ACC) or other salivary gland cancers that have come back and/or spread to other parts of the body. Researchers are also doing this study to test the …

cancer
ct scan
pembrolizumab
anticoagulants
pet scan
  • 0 views
  • 03 Jan, 2022
  • 8 locations
None
Wide-Field and High Resolution In Vivo Imaging in Visualizing Lesions in Patients With Oral Neoplasia Undergoing Surgery

This clinical trial studies wide-field and high resolution in vivo imaging in visualizing lesions in patients with abnormal or uncontrolled oral cell growth (neoplasia) undergoing surgery. Diagnostic procedures, such as wide-field and high resolution in vivo imaging, are devices that let researchers look at a wide area of the lining …

  • 191 views
  • 25 Jul, 2021
  • 1 location
None
Improved Implant for Reconstruction Purposes After Mandibular Resection

Study design: A single center non-randomized, prospective clinical feasibility study. Study population: Study population is composed of 10 patients ineligible for a free-flap bone reconstruction. Intervention: The selected patients will receive the newly developed, patient-specific RIfRaM mandibular implant. Objective: The aim is to provide enough evidence through model analysis, physical …

Accepts healthy volunteers
  • 0 views
  • 15 Jan, 2022
  • 1 location
None
A Phase II Trial of TPF Induction Chemotherapy in cN2 OSCC Patients

To confirm the subgroup result from TPF (docetaxel, cisplatin and 5-fluorouracil ) trial (NCT01542931) that cN2 OSCC patients could benefit from TPF induction chemotherapy compared to the standard treatment.

5-fluorouracil
renal function
neck dissection
cavities
carcinoma of oral cavity
  • 0 views
  • 07 Oct, 2021
  • 1 location
None
Cyclin D1 Based TPF Induction Chemotherapy for Oral Squamous Cell Carcinoma Patients at Clinical N2 Stage

The purpose of this study is to To confirm the predictive value of CCND1 for TPF induction in cN2 patients with OSCC

renal function
oral cavity cancer
carcinoma of oral cavity
chemotherapy regimen
cavities
  • 19 views
  • 04 Oct, 2021
  • 1 location
None
GDF15 Based TPF Induction Chemotherapy for OSCC Patients

The purpose of this study is to confirm the predictive value of GDF15 expression for TPF induction in T3/T4cN0M0 patients with OSCC

renal function
neck dissection
oral cavity cancer
carcinoma of oral cavity
chemotherapy regimen
  • 18 views
  • 25 May, 2021
  • 1 location
None
SPIO-enhanced MRI in Oral Cancer for Sentinel Lymph Node Identification

To explore the feasibility of sentinel lymph node identification by SPIO injection followed by MRI in head-and-neck cancer patients.

  • 0 views
  • 28 Sep, 2021
  • 1 location
None
68Ga-FAPI-04 PET/CT for the Detection of Oral Carcinoma

FAPI is a fibroblast activation protein inhibitor and 68Ga-FAPI-04 is a potential new imaging agent for imaging of carcinoma. 68Ga-FAPI-04 PET/CT is helpful to clarify the benign, malignant and invasive range of the oral carcinoma, locate and qualitatively diagnose the tumor, and make early diagnosis and restaging of recurrent tumor.

  • 0 views
  • 23 Aug, 2021
  • 1 location