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Found 84 clinical trials
Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors

This phase IV trial studies how well serial magnetic resonance imaging (MRI) after radiation therapy works in predicting radiation-induced changes in the normal tissue of patients with oral cavity or skull base tumors. Performing MRIs after radiation therapy for patients with oral cavity or skull base tumors may help to …

caries
  • 0 views
  • 26 Feb, 2022
  • 1 location
The Oral Microbiome in OSCC

understanding of how particular bacterial species, or consortia of species, can result in an individual having an increased risk of the most common type of oral cancer -- oral squamous cell carcinoma. This

oral cancer
carcinoma
squamous cell carcinoma
  • 0 views
  • 30 May, 2022
  • 1 location
Submandibular Gland Preservation in Neck Dissection

Trial design: a randomized controlled trial. Eligibility criteria for participants: patients with primary early stage oral squamous cell carcinoma. Exclusion criteria: cancer of the floor of the mouth. Interventions: submandibular gland is preserved during neck dissection for patients of the experimental group; submandibular gland is removed during neck dissection for …

neck dissection
carcinoma
squamous cell carcinoma
  • 0 views
  • 01 Mar, 2022
  • 1 location
Wide-Field and High Resolution In Vivo Imaging in Visualizing Lesions in Patients With Oral Neoplasia Undergoing Surgery

This clinical trial studies wide-field and high resolution in vivo imaging in visualizing lesions in patients with abnormal or uncontrolled oral cell growth (neoplasia) undergoing surgery. Diagnostic procedures, such as wide-field and high resolution in vivo imaging, are devices that let researchers look at a wide area of the lining …

  • 191 views
  • 14 Mar, 2022
  • 1 location
Correlation of FAZA PET Hypoxia Imaging To 3D Histology in Oral Tongue Cancer (FAITH)

This is a pilot study in the form of a prospective Phase II, single centre, single arm hypoxia study of oral tongue cancer with FAZA-PET imaging and pimonidazole targeted IHC of surgical specimens.

platelet count
neutrophil count
squamous cell carcinoma
international normalized ratio
fluoroazomycin arabinoside
  • 39 views
  • 02 Mar, 2022
  • 1 location
PSMA-PET Imaging Before and After ADT in Advanced SDC Patients (ADT-SCAN)

Explorative study, which evaluates the effect of androgen deprivation therapy (ADT) on the PSMA ligand uptake on 68Ga-PSMA-PET/CT in salivary duct carcinoma patients.

  • 1 views
  • 25 Feb, 2022
  • 1 location
Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

This research is being done to see how safe and effective the use of the study drug Ado-trastuzumab (T) emtansine (DM1), T-DM1, and standard of care chemoradiation are when used together in treating HER2-positive salivary gland cancer. It will also examine the effectiveness of study drug Ado-trastuzumab (T) emtansine (DM1) …

  • 2 views
  • 09 Jan, 2022
  • 2 locations
Exploring the Application Value of PET Molecular Imaging Targeting FAP in Oral Squamous Cell Carcinoma (FAPI-OSCC)

diagnosis and treatment. Oral cancer is the most common type of malignant head and neck cancer, seriously endangering human health. Accurate delineation of the primary tumor, detection of regional nodal

oral cancer
positron emission tomography
squamous cell carcinoma
metastasis
primary tumor
  • 0 views
  • 23 Mar, 2022
  • 1 location
Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue (PGSRT)

prospective clinical trial. Positive outcomes from this study have the potential to dramatically alter the most common morbidity of oral cancer therapy, namely speech and swallowing function in a population

cancer treatment
new diagnosis
oral cancer
  • 21 views
  • 25 Mar, 2022
  • 1 location
A Study of Drug Therapies for Salivary Gland Cancers Based on Testing of Genes

This is a study of select drug therapies in patients with salivary gland cancer. The study has two phases: a molecular profiling phase (phase 1) and a treatment phase (phase 2). Based on the Molecular profiling results in phase the participants will receive matched treatment if a specific aberration is …

  • 13 views
  • 15 Mar, 2022
  • 1 location