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Found 86 clinical trials
Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based Immunoscore (PREDICT-OLP)

Oral squamous cell carcinomas (OSCC) is among the most common malignancies worldwide. Early detection and prevention of OSCC is thought to have the highest potential to reduce morbidity and mortality. In prevention, the main focus is on precancerous lesions, especially oral leukoplakia (OLP), as up to 67% of OSCC arise …

oral leukoplakia
malignant transformation
cavity
lichen planus
cancer
  • 0 views
  • 20 Feb, 2022
Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology

technology can be used as a tool for early diagnosis of oral cancers and for guiding surgery.

oral cancer
  • 18 views
  • 28 Oct, 2022
  • 5 locations
Exploratory Study of Molecular Profile-Associated Evidence Guided Precision Therapy for Salivary Gland Cancer MAPS

To explore the feasibility, efficacy and safety of determining the treatment regimen based on genomic profiling in patients with locally advanced and advanced salivary gland cancer.

  • 0 views
  • 28 Oct, 2021
  • 1 location
Immunohistochemical & Immunoblot Analysis of NIS (Na+/I-Symporter) in Archival & Frozen Tissue Sample

The goal of this study is to study NIS expression in benign and malignant breast and thyroid samples using archival formalin-fixed paraffin-embedded tissue sections.

cancer
  • 36 views
  • 05 Jul, 2022
  • 1 location
Mass Response of Malignant Fluid Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)

The primary objective of this study, sponsored by Travera Inc. in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations using isolated tumor cells from malignant fluids such as pleural effusions and ascites.

ascites
drainage
tumor cells
combinations
pleural effusion
  • 2 views
  • 22 Oct, 2022
  • 1 location
Defining the Clinical Potential of Mass Response as a Biomarker for Patient Tumor Sensitivity to Drugs

The primary objective of this study, sponsored by Travera LLC in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations using isolated tumor cells from varying cancers and biopsy formats. Cohorts include patients with stage III or …

lung cancer
tumor cells
cancer
lung carcinoma
combinations
  • 0 views
  • 20 Oct, 2022
  • 1 location