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Found 6 clinical trials
GM-CSF Fosfomycin and Metronidazole for Pouchitis in Ulcerative Colitis Patients After Restorative IPAA Surgery

This study will examine whether the application of GM-CSF, fosfomycin and metronidazole locally in the pouch is safe and effective in the treatment of pouchitis for patients with ulcerative colitis, and whether treatment changes the microbiome of the pouch.

  • 20 Sep, 2021
  • 1 location
Study of Oral Metronidazole on Postoperative Chemotherapy in Colorectal Cancer

Fusobacterium nucleatum (Fusobacterium nucleatum, Fn) has been identified as an independent risk factor for recurrence of colorectal cancer. In this study, oral metronidazole would be used to

  • 27 Jan, 2021
  • 4 locations
The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery

The purpose of this study is to determine a difference in participant reported pain after endometriosis surgery in participants given oral metronidazole versus placebo.

Accepts healthy volunteers
endometriosis surgery
postoperative pain
  • 15 Mar, 2022
  • 1 location
Oral Antibiotics for Anal Abscess (OFF)

the follow up of patients. Patients with anal abscess will be allocated randomly either to receive 7 days of oral metronidazole/ciprofloxacin in addition to their standard care or to receive standard

  • 14 Apr, 2022
  • 1 location
Antibiotic Treatment foLlowing Surgical drAinage of Perianal abScess; the ATLAS Trial a Double-blind, Placebo-controlled, Randomized Trial (ATLAS)

> Intervention (if applicable): The antibiotic group receives 7 days of oral metronidazole (500 mg every eight hours) and ciprofloxacin (500 mg every twelve hours) in addition to surgical drainage. The other

  • 09 Jun, 2022
  • 10 locations
Phase 2 Trial of LACTIN-V in Women at High Risk of HIV Acquisition

The purpose of this study is to assess the impact of LACTIN-V, a vaginally administered live biotherapeutic product (LBP) that contains the human L. crispatus CTV-05 strain, on the vaginal microbiome of Lactobacillus-deficient young women in the South African FRESH study who are at high risk for HIV acquisition.

HIV Vaccine
vaginal product
  • 03 Sep, 2021
  • 1 location