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Found 11 clinical trials
Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome (AUSC)

Incidental findings of adrenal tumours,"incidentalomas", occur in 1-5 % in the general population and 10-25 % of these patients will exhibit biochemical mild hypercortisolism. Although the patients do not have clinical signs of classical Cushing's syndrome, they have an increased risk for hypertension, dyslipidemia, diabetes mellitus, osteoporosis and obesity. The …

  • 30 views
  • 24 Mar, 2022
  • 3 locations
Conventional Prophylactic Oral Dexamethasone vs Short-course IV Dexamethasone in Paclitaxel Hypersensitivity

randomized using the block randomization method into one of these three commonly used treatment methods:(1) Conventional method: oral dexamethasone (20 mg), taking 12 hours and 6 hours prior to paclitaxel

cancer
dexamethasone
carboplatin
paclitaxel
  • 10 views
  • 08 Jun, 2022
  • 1 location
Study of Pomalidomide Oral Dexamethasone and Ixazomib in Patients With Relapsed MM Who Have Received Lenalidomide

The purpose of this study is to evaluate the efficacy and safety of ixazomib, oral dexamethasone and in patients with relapsed multiple myeloma who have received lenalidomide.

dexamethasone
colony stimulating factor
lenalidomide
filgrastim
measurable disease
  • 0 views
  • 28 Aug, 2021
  • 1 location
Oral Dexamethasone as an Adjunct to a Brachial Plexus Block in Patients Undergoing Orthopaedic Surgery of the Forearm and Hand

We will assess the beneficial and harmful effects of oral dexamethason (12 mg or 24 mg) versus placebo in patients undergoing orthopaedic surgery of their hand or forearm with a lateral infraclavicular brachial plexus block as the means of providing anaesthesia and analgesia.

  • 0 views
  • 11 Jul, 2021
  • 2 locations
Multicohort Trial of Trabectedin and Low-dose Radiation Therapy in Advanced/Metastatic Sarcomas

withdrawal (day 2)) will be given every 3 weeks up to progression or intolerance. Premedication 4 mg oral dexamethasone 24h and 12h before trabectedin administration, 20 mg IV dexamethasone

ewing's sarcoma
neutrophil count
desmoplastic
soft tissue sarcoma
cancer chemotherapy
  • 0 views
  • 13 Dec, 2021
  • 11 locations
High Dose Oral Steroids in Sudden Sensorineural Hearing Loss

Compare hearing outcomes between treatment with dexamethasone versus prednisone in participants who have been diagnosed with unilateral SSNHL (sudden sensorineural hearing loss).

  • 312 views
  • 02 Sep, 2021
  • 1 location
A Phase I Study of Oral Metronomic Dosing of Oral Cyclophosphamide With Dexamethasone for Metastatic Castration Resistant Prostate Cancer

This phase I trial tests the safety and side effects of cyclophosphamide given together with dexamethasone in treating patients with castration resistant prostate cancer that has spread to other places in the body (metastatic). Chemotherapy drugs, such as cyclophosphamide, work in different ways to stop the growth of tumor cells, …

  • 0 views
  • 28 Oct, 2022
  • 1 location
Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity

The goal of this study is determine if an oral systemic course of steroids is a safe and effective option in lowering pain and complications following adenotonsillectomy in various pediatric age groups. A double blind, placebo-controlled randomized clinical trial of steroids (dexamethasone) versus placebo postoperatively will be performed. Investigators will …

  • 0 views
  • 22 Aug, 2021
  • 2 locations
Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients (TRASTS)

Phase I-II trial that combines trabectedin plus radiotherapy for tumor reduction response measure in two cohorts of patients: Cohort A: Patients with diagnosis of non-operable or unresectable or not oncologically recommended metastasectomy of limited to lung metastases soft tissue sarcoma. Cohort B: Patients with locally advanced resectable Myxoid Liposarcoma. Cohort …

malignant fibrous histiocytoma
measurable disease
myxoid liposarcoma
leiomyosarcoma
liposarcoma
  • 25 views
  • 17 Jun, 2022
  • 13 locations
Dexamethasone Versus Prednisone in Heart Failure Patients Hospitalized With Exacerbation of Chronic Obstructive Pulmonary Disease.

This is the first study assessing the impact of dexamethasone (a glucocorticosteroid with negligible mineralocorticoid activity) as compared to prednisone on short-term outcomes of HF patients hospitalized with exacerbation of COPD. The study may provide important data regarding a simple but potentially robust intervention among large patient population with high …

copd exacerbation
heart failure
prednisone
  • 64 views
  • 02 Apr, 2021
  • 1 location