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Found 92 clinical trials
Dissecting the Heterogeneity of Oral Cancer Pain

Oral squamous cell carcinoma (SCC) produces a higher prevalence and more severe pain than all other cancers. Orofacial pain is one of the most common initial symptoms of oral cancer and often

  • 0 views
  • 04 Sep, 2021
  • 1 location
Pharmacokinetic (PK) Analysis of Antitumor B in Patients With Oral Cancer

A Window of Opportunity Clinical Trial. This study design permits examination of effects of an oral agent on cancer patients during the "window" between diagnosis of their cancer and their definitive cancer surgery. Similar to a phase 0 study, the trial design permits examination of the biologic effects of an …

  • 6 views
  • 24 Mar, 2022
  • 1 location
Safety and Potential Efficacy of MS-20 In Combination With Pembrolizumab for the Treatment of NSCLC

MS-20 was approved as the first oral cancer adjuvant new drug indicated for ameliorating fatigue and appetite loss associated with cancer chemotherapy via reshaping human gut ecosystem and

  • 6 views
  • 16 Oct, 2021
  • 2 locations
Immune Checkpoint Inhibitor In High Risk Oral Premalignant Lesions

size or in grade of dysplasia) may not be enough to assess the potential benefit of an intervention. Modulation of molecular markers may be more precise indicator of oral cancer risk in patients with

  • 8 views
  • 27 Jan, 2021
  • 5 locations
Oral Potentially Malignant Disorders: Comparison Between Surgical Treatment and Wait and See Approach

This research protocol is comparing the effectiveness of surgical excision to the "wait and see" approach for the management of oral leukoplakia and erythroleukoplakia in prevention of oral squamous cell carcinoma onset.

  • 2 views
  • 08 May, 2021
  • 1 location
Concomitant Immune Check Point Inhibitor With Radiochemotherapy in Head And Neck Cancer

Background: Locally advanced head and neck cancer (HNC) is a challenge as, in spite of initial good control with chemoradiation, the majority of patients fails systemically. In the last 2 years, immune check points inhibitors (mainly Programmed Death (PD)-1 inhibitors) were approved for metastatic/recurrent HNC. The favorable toxicity profile and …

  • 55 views
  • 15 Feb, 2022
  • 1 location
Gross Examinations Versus Frozen Section for Assessment of Surgical Margins in Oral Cancers

Surgical margin is a significant prognostic factor in oral cavity squamous cell carcinoma (OCSCC)[1,2,3]. Intra-operative frozen section (FS) has been routinely used by the surgeons to achieve adequate surgical margins. However published literature has failed to show a conclusive benefit of FS in improving oncological outcomes(4-7). The overall identification rate …

  • 0 views
  • 12 May, 2022
  • 1 location
Enhancing Self Care Among Oral Cancer Survivors: The Empowered Survival Trial

Project's goal is evaluate an online tool the research team created called Empowered Survivor (ES) against a free online self-management intervention developed for cancer survivors by the National Cancer Institute and the American Cancer Society called Springboard Beyond Cancer.

carcinoma of oropharynx
oral cancer
oropharyngeal
  • 56 views
  • 22 Mar, 2022
  • 1 location
Androgen Deprivation Therapy in Advanced Salivary Gland Cancer

Salivary Gland (SG) Cancers are a rare and heterogeneous group of tumors, usually approached by multidisciplinary teams in high specialized centers. Until today no standard of care exists to treat these cancers. The identification of a target, the androgen receptor, in SG tumors has allowed for new treatment strategies options …

  • 177 views
  • 25 Jan, 2021
  • 25 locations
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

oral cavity cancer. Sentinel lymph node biopsy surgery is a procedure that removes a smaller number of lymph nodes from your neck because it uses an imaging agent to see which lymph nodes are most

mouth cancer
cancer
step 2
ct scan
cavity
  • 12 views
  • 22 Mar, 2022
  • 25 locations