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Found 63 clinical trials
COMT Inhibition Among Individuals With Comorbid AUD/ADHD

The purpose of this study is to determine whether the catechol-O-methyltransferase (COMT) inhibitor tolcapone, relative to placebo, affects response to alcohol, decision-making, brain activation associated with alcohol cue reactivity, response inhibition, and selective attention, or alcohol drinking.

hyperactivity
  • 0 views
  • 04 Oct, 2022
  • 1 location
Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder

Childhood ADHD and comorbid oppositional defiant disorder (ODD) and conduct disorder (CD) are considered risk factors for subsequent substance abuse, and youth with both ADHD and ODD/CD are at

substance use
methylphenidate
oppositional defiant disorder
abuse
adderall
  • 7 views
  • 09 Jun, 2022
  • 1 location
Stimulant Effects on Disruptive Behavior

The goal of this study is to determine the effects of stimulant medication on disruptive behavior, function, preference and choice; however, it is primarily methodological and will add to current research by establishing an effective evaluation of the impact of stimulant medication on these behaviors. Three behavior assessments for children …

banging head
cns stimulants
disruptive behavior disorder
Accepts healthy volunteers
hyperactivity
  • 10 views
  • 16 Feb, 2022
  • 1 location
Technology-Enhanced Executive Functioning Intervention for ADHD

This study develops and refines an online platform that will support clinician-directed behavioral and organizational skills intervention for adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD) with input guided from key stakeholders during focus groups and interviews (phase 1), extended usability testing (phase 2), and a pilot randomized trial (phase 3) of the …

hyperactivity
  • 0 views
  • 31 Oct, 2021
  • 1 location
Digital Single Session Intervention for Youth Mental Health

The aim of this study is to test the effectiveness of a single-session, digital intervention teaching the principle of practicing the opposite, when administered to youths on the waitlist for psychotherapy, with usual waitlist procedures as a control condition.

psychotherapy
Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Effect of Early Start Denver Model and Autism-adapted Parent-Child Interaction Therapy on Autism Symptoms and Disruptive Behavior in Toddlers and Preschool Children With Autism Spectrum Disorder (TAFF Pilot Study) (TAFF)

children with level 1 to level 3 ASD. PCIT has large effects on externalizing behavior problems in children with disruptive behavior disorders. Recently PCIT was adapted for children with autism spectrum

  • 0 views
  • 13 Oct, 2022
  • 1 location
Reintegration of Children From Institutions in Azerbaijan

, anxiety, PTSD, oppositional-defiant disorder, and reactive attachment disorder).

Accepts healthy volunteers
  • 0 views
  • 15 Jun, 2022
  • 1 location
Intermittent Hypoxic-hyperoxic Training in Patients With Cardiovascular Pathology After COVID-19 Infection.

Aim of this prospective, interventional, single-center, randomized study is to evaluate the efficacy and safety of intermittent hypoxic-hyperoxic training (IHHT) as a rehabilitation method in patients with cardiovascular pathology in the early period after coronavirus infection. The study will include 60 patients with cardiovascular pathology who underwent confirmed by laboratory …

diagnostic procedure
cancer
b-type natriuretic peptide
ischemia
heart failure
  • 0 views
  • 28 May, 2022
  • 1 location
Facial Affect Sensitivity Training for Young Children With Callous-unemotional Traits

-established treatments for disruptive behavior disorders. Thus, novel intervention approaches are needed to target CU traits. Youth with elevated CU traits show deficits in facial emotion recognition (FER

  • 0 views
  • 25 Feb, 2021
  • 1 location
PACT Programme for Parents of Children With SHCN

This randomised controlled trial aims to determine the efficacy of a 12-week, smartphone-based Prosocial-orientated Acceptance and Commitment Training (PACT) programme plus age-appropriate positive parenting advice on the psychological flexibility, prosociality, parenting competence and family functioning with parents of children with special health care needs as well as the mental well-being …

  • 0 views
  • 04 Oct, 2022
  • 1 location